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Chapter 26: Opioid Agonists, Opioid Antagonists, and Antimigraine AgentsAce Your Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Registered Nurse (RN) Students
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Karch’s Focus on Nursing Pharmacology, 9th Ed., Tucker | Registered Nurse (RN) School Study Aid
Chapter 26: Opioid Agonists, Opioid Antagonists, and Antimigraine Agents
15 Picmonics to Learn | 27 mins
Morphine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Pain
- Myocardial Infarction
- Side Effects
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
2 mins
Buprenorphine-Naloxone (Suboxone)
- Mechanism of Action
- Combination Drug
- Partial Opioid Receptor Agonist (Buprenorphine)
- Opioid Receptor Antagonist (Naloxone)
- Indication
- Opioid Use Disorder
- Side Effects
- CNS Depression
- Diaphoresis
- Hypotension
- Considerations
- Low Abuse Potential
2 mins
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Abuse Assessment
- Euphoria
- Miosis
- CNS Depression
- Abuse Withdrawal
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Consideration
- Naloxone
1 min
Naloxone (Narcan)
- Mechanism
- Competitive Opioid Receptor Antagonist
- Indications
- Opioid Induced CNS Depression
- Side Effects
- Severe Nausea and Vomiting
- Excitable State
- Opioid Withdrawal Symptoms
- Considerations
- Repeated Dosing Often Required
1 min
Opioid Antidote
- Antidote
- Naloxone
29 secs
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
- Mechanism
- Smooth Muscle Contraction
- Vasoconstriction
- Indications
- Migraine
- Postpartum Hemorrhage
- Side Effects
- Nausea and Vomiting
- Severe Hypertension
- Tachycardia
- Considerations
- 2nd Line Agent
2 mins
Sumatriptan
- Mechanism of Action
- Short Half-Life
- 5-HT Agonist
- Inhibits Trigeminal Nerve Activation
- Induces Vasoconstriction
- Indications
- Migraine
- Cluster Headache
- Side Effects
- Increased Risk of Serotonin Syndrome
- Paresthesias
- Coronary Vasospasm
- Contraindication
- Prinzmetal's Angina
- Coronary Artery Disease (CAD)
3 mins
Tramadol
- Indications
- Chronic Pain
- Mechanism of Action
- Weak Opioid
- Inhibit Serotonin and NE reuptake
- Side Effect
- Increased Risk of Seizure
48 secs
Meperidine (Demerol)
- Mechanism
- Opioid Receptor Agonist
- Indications
- Moderate to Severe Pain
- Post Anesthesia Shivering
- Side Effects
- Tremors
- Constipation
- CNS Depression
- Sedation
- Considerations
- Short Term Administration
- Increased Risk Serotonin Syndrome
- Does NOT cause Miosis
- Renal Failure Increases Toxicity Risk
2 mins
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Pain Assessment
- Types of Pain
- Acute Pain
- Chronic Pain
- OPQRST Mnemonic
- Onset
- Provoking or Palliative
- Quality
- Radiation
- Severity
- Timing
- Nursing Considerations
- Subjective Findings
- Objective Findings
- Reassessment of Pain
2 mins
Codeine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Mild to Moderate Pain
- Cough Suppressant
- Side Effects
- Sedation
- Constipation
- Miosis
- Considerations
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
2 mins
Oxycodone
- Mechanism of Action
- Opioid Receptor Agonist
- Indication
- Refractory Pain
- Side Effects
- Respiratory Depression
- Constipation
- CNS Depression
- Considerations
- Addiction
- Naloxone
2 mins
Fentanyl
- Mechanism of Action
- Opioid Receptor Agonist
- High Potency
- Indications
- Anesthesia Induction
- Chronic Pain
- Breakthrough Pain
- Side Effects
- CNS Depression
- Respiratory Depression
- Constipation
- Miosis
- Considerations
- Addiction
3 mins
Acetaminophen-Hydrocodone (Vicodin)
- Mechanism of Action
- Combination Analgesic
- Opioid Receptor Agonist
- Hydrocodone
- Reversible Inhibition of COX
- Acetaminophen
- Indication
- Moderate to Severe Pain
- Side Effects
- CNS Depression
- Respiratory Depression
- Hepatotoxicity
- Considerations
- Addiction
2 mins
