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Practical Nurse (LPN)
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Pathoma: Fundamentals of Pathology (2018)
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Acute Inflammation

Ace Your Pathoma: Fundamentals of Pathology (2018) Classes and Exams with Picmonic: #1 Visual Mnemonic Study Tool for Practical Nurse (LPN) Students

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Pathoma: Fundamentals of Pathology (2018) | Practical Nurse (LPN) School Study Aid

Acute Inflammation
6 Picmonics to Learn | 15 mins
Inflammatory Response
Pathogens Infect Tissue
Mast Cells Release Histamine
Histamine Dilates and Increases Capillary Permeability
Macrophages Engulf Pathogens
Macrophage Signals Cells With Cytokines
Responding Neutrophils Cross Capillary Wall
B And T Lymphocytes Arrive At Injury Site
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2 mins
Complement Disorders
Early Complement Deficiency
Pyogenic Infections
SLE
Sinus Infections
Terminal Complement Deficiency
Autosomal Recessive
Neisseria Infections
C5-C9
MAC (Membrane Attack Complex)
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4 mins
Chronic Granulomatous Disease
Pathophysiology
Most Commonly X-linked Recessive
Defective NADPH Oxidase (Enzyme Complex)
Decreased Hydrogen Peroxide
Impaired Intracellular Killing in Phagocytes
Signs and Symptoms
Recurrent Purulent Skin and Lung Infections
Catalase Positive Organisms
Diagnosis
Negative Nitroblue Tetrazolium Test
DHR (Dihydrorhodamine) Flow Cytometry
Treatment
Antimicrobial Prophylaxis
TMP-SMX
Itraconazole
Interferon-Gamma
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3 mins
Innate Immunity Cellular Response
Characteristics
Natural Killer Lymphocytes Attack Abnormal Cells
Neutrophils in Blood
Infected Cells Release Interferon
Complement Proteins Lyse Pathogens/Infected Cells
Dendritic Cells in Tissue
Macrophages in Tissue
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2 mins
Cell-mediated Adaptive Immune Response
Characteristics
Macrophages and Dendritic Cells Present Antigens
T Cell Develops Antigen Specificity
Regulatory T Cells Suppress Response
Memory T Cells Cause Faster Secondary Response
Cytotoxic T Cells Lyse Infected Cells
Infected Cells Present Antigen On Surface
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2 mins
Cardinal Signs of Inflammation
Redness (Rubor)
Warmth (Calor)
Swelling (Tumor)
Pain (Dolor)
Loss of Function (Functio laesa)
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1 min

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