Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher |  Practical Nurse (LPN) School Study Aid
Haloperidol (Haldol)
- High Potency Antipsychotic
 - Migraine
 - Schizophrenia
 - Extrapyramidal Symptoms
 - Weight Gain
 - QT Prolongation
 - Restlessness
 - Caution in Seizure Patients
 - Neuroleptic Malignant Syndrome
 
Hydrochlorothiazide HCTZ
- Inhibits Reabsorption NaCl and H2O
 - Edema
 - Mild to Moderate Hypertension
 - Hypokalemia
 - Hyponatremia
 - Dehydration
 - Hyperglycemia
 - Gout
 - Sulfa Allergy
 - Pregnancy and Breastfeeding
 
Chlorpromazine (Thorazine)
- Low Potency Antipsychotic
 - Schizophrenia
 - Hiccups
 - Sedation
 - Weight Gain
 - Orthostatic Hypotension
 - Anticholinergic Effects
 - QT Prolongation
 - Neuroendocrine Effects
 - Caution in Seizure Patients
 - Corneal Deposits
 
Chlorpropamide and Tolbutamide (Orinase) (1st Generation Sulfonylureas)
- 1st Generation Sulfonylureas
 - Stimulate Release of Insulin
 - Type 2 Diabetes
 - Hypoglycemia
 - Possible Cardiovascular Toxicity
 - Weight Gain
 - Exacerbated Hypoglycemia with Beta-blockers
 - Avoid During Pregnancy and Breast Feeding
 - Avoid Alcohol
 
Glyburide and Glipizide (2nd Generation Sulfonylureas)
- 2nd Generation Sulfonylureas
 - Blocks Potassium Channels in Beta Cells
 - Stimulate Release of Insulin
 - Type 2 Diabetes
 - Hypoglycemia
 - More Potent
 - Beta Blockers Reduce Effects
 - Avoid Alcohol
 - Avoid Breastfeeding
 
Griseofulvin
- Disrupts Microtubules in Mitosis
 - Antifungal for Superficial Infections
 - Tinea and Ringworm
 - Teratogen
 - P450 Inducer
 - Confusion
 - Headache
 
Tetracyclines Overview
- End in "-cycline"
 - Bacteriostatic
 - Infectious Diseases
 - Acne
 - Periodontal Disease
 - Avoid Milk, Antacids, Iron
 - Sunlight Protection
 
Tetracyclines Side Effects
- Superinfection
 - Clostridioides difficile
 - Discoloration of Teeth
 - Bone Deformities
 - Photosensitivity
 - Children Under 8
 - Pregnancy
 
Methotrexate
- Rheumatoid Arthritis
 - Cancer
 - Medical Abortion
 - Folic Acid Analog
 - Inhibits Dihydrofolate Reductase
 - Pulmonary Fibrosis
 - Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
 - Macrocytic Anemia
 - Hepatitis
 - Teratogenic
 - Mucositis
 
Azoles (Ketoconazole)
- "-azole" suffix
 - Local and Less Serious Systemic Mycosis
 - Inhibits Ergosterol Synthesis
 - Inhibits P450
 - Liver Dysfunction
 - Inhibition of Testosterone Synthesis
 
Fluoroquinolones
- End in "-floxacin"
 - Bactericidal
 - Variety of Infections
 - GI Distress
 - Photosensitivity
 - Achilles Tendon Rupture
 - Pregnancy
 - Children
 - Myasthenia Gravis
 - Avoid Milk Products or Antacids
 - Slow IV Infusion
 
Chloramphenicol (Chloromycetin)
- Bacteriostatic
 - Gram Positive or Gram Negative Infections
 - Bone Marrow Suppression
 - Aplastic Crisis
 - Gray Syndrome
 - Toxicity Limits Use
 - Monitor Blood Counts
 
Vitamin C (Ascorbic Acid)
- Antioxidant
 - Collagen Formation
 - Steroid Synthesis
 - Dietary Deficiency
 - Scurvy
 - GI Distress
 - Citrus Fruits
 - May Improve Healing
 
Vitamin B3 - Niacin (Nicotinic Acid)
- Decreases Triglycerides
 - Decreases LDL
 - Increases HDL
 - Dyslipidemia
 - Pellagra
 - Diarrhea
 - Dermatitis
 - Dementia
 - Flushing
 - GI Distress
 - Hepatotoxicity
 
Vitamin K1 (Phytonadione)
- Synthesizes Clotting Factors II, VII, IX, X
 - Hypoprothrombinemia
 - Newborn Prophylaxis
 - Bleeding from Warfarin Overdose
 - Shock
 - Kernicterus
 - Cardiac Arrest
 - Bile Salts required for Intestinal Absorption
 - Increased Risks with IV Administration
 
Vitamin A (Retinol)
- Maintains Mucous Membranes
 - Eyes and Skin
 - Dietary Deficiency
 - Skin Disorders
 - Hepatosplenomegaly
 - Jaundice
 - Increased ICP
 - Vomiting
 - Teratogen
 - Animal Food Products
 - Dark Green and Orange Fruits/Vegetables
 
Cholecalciferol (Vitamin D3)
- Vitamin D3
 - Dietary Supplement
 - Vitamin D Deficiency
 - Fatigue
 - Constipation
 - Hypercalcemia
 - Kidney Stones
 - More Effective Than Ergocalciferol
 - Hypervitaminosis D
 
Vitamin B6 (Pyridoxine)
- Converted to Pyridoxal Phosphate
 - Amino Acid and Protein Metabolism
 - Heme Synthesis
 - Neurotransmitter Synthesis
 - Niacin Synthesis
 - Isoniazid Induced Neuropathy
 - Sideroblastic Anemia
 - Premenstrual Syndrome (PMS)
 - Levodopa
 - Neuropsychiatric Symptoms
 - Cereals and Meats
 
ABCDEs of Melanoma
- Asymmetry
 - Border
 - Color
 - Diameter
 - Evolving
 
Cephalosporins
- Starts with "Cef-"
 - Bactericidal
 - Gram-Positive and Gram-Negative Infections
 - Allergic Reactions
 - Thrombophlebitis
 - Bleeding
 - Renal Impairment
 - Avoid IV Calcium with Ceftriaxone
 - No Alcohol
 
Vancomycin
- Inhibits Bacterial Cell Wall Synthesis
 - Serious Gram-Positive Infections
 - Nephrotoxicity
 - Ototoxicity
 - Red Man Syndrome
 - Thrombophlebitis
 - Culture Samples First
 - Infuse IV Over 60 Minutes
 - Take Around the Clock
 
Genital Herpes
- Herpes Simplex Virus 1 and 2 (HSV)
 - May Be Asymptomatic
 - Oral or Genital Lesions
 - Vesicles in Clusters
 - Pain
 - Flu-like Symptoms
 - Acyclovir
 - Valacyclovir
 - Famciclovir
 - Infectious During Recurrences
 
Acyclovir (Zovirax)
- Guanosine Analog
 - Inhibits Viral Replication
 - Thymidine Kinase Activation
 - Herpes Simplex Virus (HSV)
 - Varicella Zoster Virus (VZV)
 - Headache
 - GI Distress
 - CNS Toxicity
 - Nephrotoxicity (Crystalline Nephropathy)
 - Prevents Recurrent Episodes
 - Slow IV Infusion
 
Herpes Zoster (Shingles)
- Varicella-Zoster Virus
 - Linear, Unilateral Rash Along a Dermatome
 - Pruritus
 - Postherpetic Neuralgia
 - Acyclovir
 - Analgesics
 - Gabapentin
 - Contagious Vesicles
 - Shingrix
 
Gabapentin
- Seizure Treatment
 - Peripheral Neuropathy
 - Postherpetic Neuralgia
 - Bipolar Disorder
 - Migraine Prophylaxis
 - Inhibits Voltage-Gated Ca2+ channels
 - Designed as a GABA Analog
 - Ataxia
 - Sedation
 
Prednisone (Glucocorticoids)
- Glucocorticoid
 - Inflammatory Conditions
 - Organ Transplant Rejection
 - Cataracts and Glaucoma
 - Cushing's Syndrome
 - Osteoporosis
 - Immunosuppression
 - Hyperglycemia
 - Ulcers
 - Adrenal Insufficiency
 - Taper Gradually
 
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
- Topical Antimicrobial
 - Burns
 - Open Wound Care
 - Mafenide
 - Pain
 - Acidosis
 - Administer Analgesic Prior to Wound Care