Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher |  Practical Nurse (LPN) School Study Aid
Inflammatory Response
- Pathogens Infect Tissue
 - Mast Cells Release Histamine
 - Histamine Dilates and Increases Capillary Permeability
 - Macrophages Engulf Pathogens
 - Macrophage Signals Cells With Cytokines
 - Responding Neutrophils Cross Capillary Wall
 - B And T Lymphocytes Arrive At Injury Site
 
WBC Differential Lab Value
- White Blood Cells (WBC)
 - 4.5-11 (4,500-11,000)
 - Segmented Neutrophils (54%-62%)
 - Band Neutrophils  (3%-5%)
 - Lymphocytes (25%-33%)
 - Monocytes (3%-7%)
 - Eosinophils (1%-3%)
 - Basophils (0%-0.75%)
 
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Depression
 - Diabetic Peripheral Neuropathy
 - Duloxetine
 - Panic and Anxiety
 - Venlafaxine
 - Inhibits Reuptake of Serotonin and NE
 - Hypertension
 - Insomnia
 - Nausea and Vomiting
 - Decreased Libido
 
Fever
- Flushed skin, warm to touch
 - Chills
 - Sweating
 - Change in LOC
 - Provide adequate fluids
 - Monitor Electrolytes and Fluid
 - Monitor vital signs, esp temperature
 - Remove excess clothing and blankets
 - Sponge bath with tepid water
 
Acetaminophen
- Fever
 - Pain
 - Reversibly Inhibits COX
 - Acts Primarily in CNS
 - Hepatic Necrosis
 - N-acetylcysteine Antidote
 
Aspirin (Acetylsalicylic Acid)
- Inhibits Platelet Aggregation
 - NSAID
 - Thrombotic Event Prevention
 - General Pain
 - Inflammatory Conditions
 - Fever
 - Pancytopenia
 - GI Ulcers
 - Bleeding
 - Withhold Before Surgery 7-10 Days
 - Reye's Syndrome
 
Ibuprofen (Advil, Motrin)
- NSAID
 - COX Inhibitor
 - General Pain
 - Fever
 - Inflammatory Conditions
 - GI Ulcers
 - Nephrotoxicity
 - Rash
 - Avoid with Alcohol
 - Risk of Thrombotic Event
 
Prednisone (Glucocorticoids)
- Glucocorticoid
 - Inflammatory Conditions
 - Organ Transplant Rejection
 - Cataracts and Glaucoma
 - Cushing's Syndrome
 - Osteoporosis
 - Immunosuppression
 - Hyperglycemia
 - Ulcers
 - Adrenal Insufficiency
 - Taper Gradually
 
Vitamin C (Ascorbic Acid)
- Antioxidant
 - Collagen Formation
 - Steroid Synthesis
 - Dietary Deficiency
 - Scurvy
 - GI Distress
 - Citrus Fruits
 - May Improve Healing
 
Vitamin A (Retinol)
- Maintains Mucous Membranes
 - Eyes and Skin
 - Dietary Deficiency
 - Skin Disorders
 - Hepatosplenomegaly
 - Jaundice
 - Increased ICP
 - Vomiting
 - Teratogen
 - Animal Food Products
 - Dark Green and Orange Fruits/Vegetables
 
NSAIDs
- Anti-inflammatory
 - Analgesic
 - Fever
 - Closure of Patent Ductus Arteriosus 
 - Reversible Inhibition of COX-1 and COX-2
 - Block Prostaglandin Synthesis
 - Interstitial Nephritis
 - Gastric Ulcer
 - Renal Ischemia
 
Types of Wound Healing
- Acute
 - Chronic
 - Primary Intention
 - Approximated Edges
 - Secondary Intention
 - Edges Not Approximated
 - Tertiary Intention
 - Delayed Closure due to Infection and Necrosis
 
R.I.C.E. (Treating Soft Tissue Injury)
- Rest
 - Ice
 - Compression
 - Elevation
 
Pressure Ulcers
- Prolonged Immobilization
 - Neurologic Disease
 - Decreased Level of Consciousness
 - Stage 1: Intact Skin with Non-blanchable Erythema
 - Stage 2: Partial Thickness Skin Loss
 - Stage 3: Full-thickness Skin Loss without Fascial Involvement
 - Stage 4: Full-thickness Skin Loss with Fascial Involvement
 - Wound Care
 - Surgery
 - Septicemia
 - Osteomyelitis
 - Prevention
 
Braden Scale
- Sensory Perception
 - Moisture
 - Activity
 - Mobility
 - Nutrition
 - Friction and Shear
 
Interventions for Impaired Skin Integrity
- Signs of Skin Breakdown
 - Pain
 - Redness
 - Decreased Skin Turgor
 - Bleeding
 - Bony Prominences
 - Reposition Q2H
 - Pressure Relief
 - Maintain Clean and Dry Skin
 - Adequate Nutrition and Hydration