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Medicine (MD/DO)
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First Aid
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First Aid for the USMLE Step 1 (2024)
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Page 497 -

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First Aid for the USMLE Step 1 (2024) | Medicine (MD/DO) School Study Aid

Page 497 -
4 Picmonics to Learn | 7 mins
TNF-Alpha Inhibitors Overview
Mechanism
Downregulates Pro-inflammatory Cytokines
Decreased Lymphocyte Activation and Migration
Granuloma Breakdown
Treats
Crohn's Disease
Rheumatoid Arthritis
Juvenile Rheumatoid Arthritis
Psoriasis
Ankylosing Spondylitis
picmonic thumbnail
1 min
TNF-Alpha Inhibitor Drugs and Complications
Etanercept
Decoy TNF- Alpha receptor
Anti-TNF- Alpha antibody
Adalimumab
Infliximab
Complications
Increased risk of infection
Predispose to Tuberculosis (TB) reactivation
Order Baseline PPD- skin test
Quantiferon Gold In-Tube
Order Chest X-Ray
picmonic thumbnail
2 mins
Psoriasis Pharmacology
Cyclosporine
Methotrexate
Topical Agents
Antibody Therapy
Infliximab
Adalimumab
Etanercept
Guselkumab
Natalizumab (Tysabri)
Ustekinumab
Ixekizumab
Secukinumab
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2 mins
Psoriasis
Presentation
Epidermal Hyperproliferation Keratinocytes
Defined Red Salmon Plaques
Silvery Scales
Extensor Surfaces
Bleeding when Removed
Auspitz Sign
Pruritus
Nail Changes
Histological Finding
Munro Microabscesses
Nucleated Cells in Stratum Corneum
Treatment
Retinoids
Topical Corticosteroids
Tar
Immunosuppressants
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2 mins

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