🐸
LEAP YEAR SALE SAVE 25% NOW
Medicine (MD/DO)
/
First Aid
/
First Aid for the USMLE Step 1 (2023)
/
Page 339 -
/
Peripheral Precocious Puberty

Master Peripheral Precocious Puberty with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

DOWNLOAD PDF
Peripheral Precocious Puberty

Recommended Picmonics

picmonic thumbnail
Central Precocious Puberty
picmonic thumbnail
Steroid Hormones
picmonic thumbnail
21 Hydroxylase Deficiency
picmonic thumbnail
11 Beta-Hydroxylase Deficiency

Peripheral Precocious Puberty

Peripheral Pubescent-baby
DikeHAfifi
12 KEY FACTS
CHARACTERISTICS
Secondary Sex Characteristics before 8 Years (Girls) or 9 Years (Boys)
(2) Tutu Sex-symbol Less-than (8) Ball or (9) Lives-cat

Precocious puberty is defined as an early onset of puberty. Precocious puberty is diagnosed in girls if signs of puberty occur before they are 8 years old and in boys if signs appear before 9 years of age.

Breast Development (Girls) or Testicular Enlargement (Boys)
Breast Development or Testicular Enlargement

The onset of puberty is defined by the appearance of secondary sexual characteristics, which may include breast development in girls and testicular and penile enlargement in boys.

GnRH Independent
Gonad-gopher Independence-protest

Peripheral precocious puberty is characterized by a precocious development of secondary sexual characteristics independent from the GnRH pulsatile secretion. This aspect of peripheral precocious puberty differs from central precocious puberty, which occurs due to excessive GnRH production.

ETIOLOGIES
Congenital Adrenal Hyperplasia
Present-at-birth Adrenal-hat Hiker-plates

Untreated congenital adrenal hyperplasia patients can experience peripheral precocious puberty. Sex hormone levels can be found to vary depending on the adrenal enzyme block.

Exogenous Sex Steroids
Exit Steroid-stairs Sex-symbol

Exogenous sex steroids can cause excess sex hormones, resulting in peripheral precocious puberty. Feminization can occur due to the use of estrogen preparations. Virilization in both sexes can occur due to topical androgens.

Granulosa Cell Tumor
Granny-lotus with Tumor

Granulosa cell tumor is a slow-growing ovarian tumor that produces high estrogen. This excess estrogen can result in peripheral precocious puberty. The patient can experience breast enlargement and menstrual irregularities.

Non-Germ Cell Tumor
Non-germy Ovary

Non-germ cell tumor is one of the causes of peripheral precocious puberty.

DIAGNOSTIC FEATURES
GnRH Stimulation Test
Gonad-gopher Stim-mule

The GnRH stimulation test is the gold standard for diagnosing precocious puberty. This test determines the hypothalamic-pituitary axis's reactivity to the presence of increased gonadotropin (LH and FSH) levels after injection of GnRH.

No Increase in LH
Cross-sign of Up-arrow Luge

Basal LH concentration, measured ideally in the morning, will be a good initial screening test to differentiate between central and peripheral precocious puberty. Peripheral precocious puberty will show no increased LH. The concentration of LH in the prepubertal range will be <0.2 mIU/mL. It can be diagnosed as a peripheral precocious puberty or a benign pubertal variant (e.g., premature thelarche).

Bone Age
Bone Birthday-cake (Age)

Bone age, utilizing radiography of the hand and wrist, can be used to determine the likelihood of precocious puberty as well as its progression. Diagnosis can be made if bone age is 2 years older relative to the child's age.

Hormone Levels
Harmonica

Hormone levels can help in diagnosing peripheral precocious puberty. FSH concentrations are found to be low in patients. High estradiol or high testosterone concentration with suppression of gonadotropins can indicate peripheral precocious puberty.

MANAGEMENT
Treating Underlying Disorders
Treating Disorders Under the Table

If patients are found to have an underlying disorder that causes peripheral precocious puberty, treating the underlying disorder is the mainstay of treatment.

DOWNLOAD PDF

Take the Peripheral Precocious Puberty Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Memorize facts with phonetic mnemonics

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,860,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.