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DOWNLOAD PDFPhase 0 is characterized by depolarization.
Phase 0 is described by the upstroke, opening of voltage-gated calcium (Ca2+) channels, which results in a rapid influx of calcium. This process will result in depolarization.
The opening of voltage-gated calcium (Ca2+) channels results in a rapid influx of calcium. Permanent inactivation occurs in fast voltage-gated sodium (Na+) channels due to these cells' less negative resting potential. This process will cause the AV node's slow conduction velocity to extend transmission from the atria to the ventricles.
Phase 1 and 2 are absent. Phase 3 is characterized by repolarization.
Phase 3 is described by the inactivation of the calcium (Ca2+) channels and the increased activation of potassium (K+) channels, resulting in the efflux of potassium. This process will result in repolarization.
The inactivation of the calcium (Ca2+) channels and the increased activation of potassium (K+) channels cause an efflux of potassium.
Phase 4 is characterized by depolarization.
Phase 4 is characterized by the presence of a funny current, which is responsible for the slow, mixed Na+ inward/K+ outward current, resulting in a slow influx of sodium.
The presence of a funny current, which is responsible for the slow, mixed Na+ inward/K+ outward current, results in a slow influx of sodium.
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