Acetaminophen
- Fever
 - Pain
 - Reversibly Inhibits COX
 - Acts Primarily in CNS
 - Hepatic Necrosis
 - N-acetylcysteine Antidote
 
Acetylcholinesterase Inhibitor Poisoning
- DUMBBELSS
 - Diarrhea
 - Urination
 - Miosis
 - Bronchospasm
 - Bradycardia
 - Emesis
 - Lacrimation
 - Salivation
 - Sweating
 
Acetylcholinesterase Inhibitor Antidote
Atropine
- Blocks DUMBBeLSS
 - Bradycardia
 - Skin Flushing
 - Increased Temperature
 - Dry Mouth
 - Cycloplegia
 - Disorientation
 - Mydriasis
 
Arsenic, Gold and Copper Antidotes
- Arsenic
 - Gold
 - Copper
 - Penicillamine
 - Dimercaprol (BAL)
 - Succimer
 
Benzodiazepines Overview
- First Line for Status Epilepticus
 - Anesthesia Induction
 - Anxiety
 - Eclampsia
 - Detoxification
 - '-zepam' and '-zolam' Suffix
 - Increase Frequency of Cl- Channel Opening
 - Decrease REM Sleep
 - CNS Depression
 - Dependence
 - Flumazenil for Overdose
 
Systemic Effects of Beta-Blockers
- Respiratory
 - Bronchoconstriction
 - Metabolic
 - Decreased Insulin
 - Decreased Glycolysis and Lipolysis
 - Eye
 - Reduces Intraocular Pressure
 
Cyanide Poisoning Diagnosis and Treatment
- Lactic Acidosis
 - Elevated Venous PO2
 - Check Carboxyhemoglobin
 - Sodium Nitrate PLUS Sodium Thiosulfate
 - Methemoglobinemia
 - OR Hydroxocobalamin (First Line)
 
Acute Digoxin Toxicity
- Hyperkalemia
 - Cholinergic (Nausea, Vomiting, Diarrhea)
 - Blurry Yellow Green Vision with Halo of Light
 - Arrhythmia
 - Bradycardia
 - Prolonged PR interval
 - Decreased QT
 - Scooping on EKG
 - T Wave Inversion
 
Digoxin Toxicity Treatment
- Activated Charcoal
 - Slowly Normalize K+
 - Digibind (Anti-Digoxin Fab)
 - Magnesium Sulfate
 - Lidocaine
 - Cardiac Pacing
 
Heparin Mechanisms
- Short Half-life
 - Antithrombin Activation Cofactor
 - Decrease Thrombin, Factor Xa
 - Bleeding
 - Heparin Induced Thrombocytopenia (HIT)
 - Protamine Sulfate
 
Iron (Ferrous Sulfate)
- Ferrous Salts
 - Anemia
 - GI Distress
 - Nausea and Vomiting
 - Dark Stools
 - Take Between Meals
 - Liquid can Stain Teeth
 - Keep out of Reach from Children
 - Caution with GI Disorders
 - Avoid Antacids
 
Lead Antidotes
- Dimercaprol
 - CaEDTA
 - Succimer
 
Methotrexate
- Rheumatoid Arthritis
 - Cancer
 - Medical Abortion
 - Folic Acid Analog
 - Inhibits Dihydrofolate Reductase
 - Pulmonary Fibrosis
 - Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
 - Macrocytic Anemia
 - Hepatitis
 - Teratogenic
 - Mucositis
 
Opioids Overview
- Pain
 - Weaning
 - Cough
 - Diarrhea
 - Agonists at  Mu (μ), Kappa (Κ), and Delta (δ) Receptors
 - Decrease Synaptic Transmission
 - Respiratory Depression
 - Addiction
 - Miosis
 - Constipation
 
Aspirin Poisoning (Salicylism) Assessment
- Nausea and Vomiting
 - Tinnitus
 - Confusion
 - Hyperventilation
 - Respiratory Alkalosis
 - Metabolic Acidosis
 - Coma
 - Hyperthermia
 
Tricyclic Antidepressants (TCAs) Overview
- Blocks Serotonin and NE Reuptake
 - Lipid-soluble
 - Adverse CNS Effects
 - Anticholinergic
 - Antihistamine
 - Tri-C: Convulsion, Coma, Cardiotoxicity
 - Blocks Alpha1 Receptors
 
Tricyclic Antidepressant (TCA) Antidote
- Sodium Bicarbonate (NaHCO3)
 
Warfarin
- Interferes with Vitamin K-dependent Clotting Factors
 - Extrinsic Pathway
 - Bridge with Heparin
 - Chronic Anticoagulation
 - Bleeding
 - Necrosis
 - Cytochrome P450
 - Pregnancy
 - FFP + Vitamin K
 
Warfarin Antidotes
- Vitamin K
 - Fresh Frozen Plasma
 
Amphetamines Intoxication Assessment
- Euphoria
 - Insomnia
 - Mydriasis
 - Diaphoresis
 - Hypertension
 - Tachycardia
 - Paranoia
 - Anxiety
 - Anorexia
 - Seizures
 
Amphetamine Antidote
- Ammonium Chloride (NH4Cl)
 - Acidify Urine
 
Sumatriptan
- Short Half-Life
 - 5-HT Agonist
 - Inhibits Trigeminal Nerve Activation
 - Induces Vasoconstriction
 - Migraine
 - Cluster Headache
 - Increased Risk of Serotonin Syndrome
 - Paresthesias
 - Coronary Vasospasm
 - Prinzmetal's Angina
 - Coronary Artery Disease (CAD)
 
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
- Smooth Muscle Contraction
 - Vasoconstriction
 - Migraine
 - Postpartum Hemorrhage
 - Nausea and Vomiting
 - Severe Hypertension
 - Tachycardia
 - 2nd Line Agent
 
Vancomycin Side Effects & Toxicity
- Thrombophlebitis
 - Nephrotoxicity
 - Ototoxicity
 - Diffuse Flushing Called Red Man Syndrome
 - Prevent with Antihistamine
 - Prevent with Slow Infusion
 
Torsades de Pointes
- Polymorphic Ventricular Tachycardia
 - Prolonged QT Interval
 - QRS Twist Around Isoelectric Line
 - Congenital
 - Antibiotics
 - Antiarrhythmics
 - Antipsychotics
 - Antidepressants
 - Electrolyte Deficiencies
 - Ventricular Fibrillation
 - Stable: Magnesium Sulfate
 - Unstable: Defibrillation