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Medicine (MD/DO)
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First Aid
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First Aid for the USMLE Step 1 (2019)
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First Aid for the USMLE Step 1 (2019) | Medicine (MD/DO) School Study Aid

Page 435 -
4 Picmonics to Learn | 7 mins
Rituximab
Indications
Chronic Lymphocytic Leukemia (CLL)
Non-Hodgkin Lymphoma
Rheumatoid Arthritis
Microscopic Polyangiitis (MPA)
Granulomatosis with Polyangiitis (Formerly Wegener's)
Mechanism
Monoclonal Antibody Against CD20
Found on B Cell Neoplasms
Side Effects
Infusion Reactions
Skin and Mouth Reactions
Reactivation of Hepatitis B Virus (HBV)
Progressive Multifocal Leukoencephalopathy (PML)
picmonic thumbnail
3 mins
Tamoxifen
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Antagonist on Breast Tissue
Indications
ER-positive Breast Cancer
Side Effects
Decreased Risk of Osteoporosis
Increased Risk of Endometrial Cancer
Increased Risk of Venous Thromboembolism (VTE)
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1 min
Trastuzumab
Indications
HER-2+ Breast Cancer
Stomach Cancer
Mechanism
Monoclonal Antibody Against HER-2
Inhibition of Cellular Signaling
Cytotoxicity
Side effects
Cardiotoxicity
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1 min
Melanoma Diagnosis
Signs
ABCDE Mnemonic
Asymmetry
Border irregularity
Color variation
Diameter > 6mm
Evolution over time
Diagnosis
S-100 Tumor Marker
LDH (Lactate Dehydrogenase) Screens for Metastasis
Treatment
Wide Local Excision
Adjuvant Therapy
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1 min

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