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Physiology | Medicine (MD/DO) School Study Aid


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Fundamentals of Gastrointestinal Physiology
4 Picmonics to Learn | 10 mins

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Secretin
Synthesis
Secreted from S Cells in Duodenum
Regulation
Stimulated by Fatty Acids in Duodenum
Functions
Increases Bicarbonate Secretion
Increases Bile Acid Secretion
Decreases Gastric Acid
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2 mins
Cholecystokinin (CCK)
Secreted by I Cells
Duodenum and Jejunum
Physiology
Increase Pancreatic Secretions
Increase Gallbladder Contraction
Induce Relaxation of Sphincter of Oddi
Decrease Gastric Emptying
Regulation
Increased by Fatty Acids and Amino Acids
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1 min
Somatostatin
Secreted by D Cells
Pancreas
GI Tract
Action
Decrease Secretion of Gastric Acid and Pepsinogen
Decrease Pancreatic and Small Intestine Fluid Secretion
Decrease Gallbladder Contraction
Decrease Glucagon and Insulin Secretion
Regulation
Secretion is Increased by Acid
Secretion is Decreased by Vagal Stimulation
Clinical Use
Octreotide
Carcinoid Syndrome
Variceal Bleeds
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2 mins
Bile
Synthesis and Circulation
Synthesized Continuously By Hepatocytes
Cholesterol 7 Alpha-Hydroxylase Rate Limiting Step
Stored In Gallbladder
Secreted Into Duodenum
Bile Salts Reabsorbed In Terminal Ileum
Returned To Liver Via Portal Circulation
Composition
Bilirubin
Bile Salts
Cholesterol And Phospholipids
Ions And Water
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4 mins

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