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Pathology | Medical (MD/DO) School Study Aid
Actinic Keratosis
- Sun Exposure
- Papules or Plaques
- Small, Rough
- Erythematous
- Precursor to Squamous Cell Carcinoma
53 secs
Squamous Cell Carcinoma of the Skin
- Epidemiology
- 2nd Most Common Skin Cancer
- UV Light Exposure
- Long-term Immunosuppression
- Arsenic Exposure
- Signs/Symptoms
- Ulcerative Red Lesion
- Precursor Actinic Keratosis
- Commonly Lower Lip
- Diagnosis
- Biopsy shows Keratin Pearls
- Treatment
- Mohs Micrographic Surgery
2 mins
Basal Cell Carcinoma of the Skin
- Pathophysiology
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Diagnosis
- Shave Biopsy
- Pallisading Nuclei
- Treatment
- Mohs Micrographic Surgery
2 mins
Melanoma Mechanism and Characteristics
- Mechanism
- Associated with Sunlight Exposure
- Mutation in B-RAF kinase
- Large Number of Moles
- Fair-Skinned people at higher risk
- Growth Phases
- Radial Growth Phase
- No Metastasis
- Vertical Growth Phase
- Depth of tumor correlates with risk of metastasis
1 min
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
1 min
Melanoma Diagnosis
- Signs
- ABCDE Mnemonic
- Asymmetry
- Border irregularity
- Color variation
- Diameter > 6mm
- Evolution over time
- Diagnosis
- S-100 Tumor Marker
- LDH (Lactate Dehydrogenase) Screens for Metastasis
- Treatment
- Wide Local Excision
- Adjuvant Therapy
1 min
Types of Malignant Melanoma
- Superficial Spreading
- Most Common Cause of Melanoma
- Nodular
- Aggressive and Rapidly Arising
- Acral-Lentiginous
- Males
- Asians and African Americans
- Lentigo Maligna
- Geographic Shape
- Sun Exposed Areas
2 mins
Keratoacanthoma
- Low-Grade Skin Tumor
- Dome-shaped Nodule with Central Crater
- More Common in Elderly
- Sun-exposed Skin
- Characteristics
- Resembles Squamous Cell Carcinoma of the Skin
- Grows Rapidly over 4-6 Weeks
- Workup & Management
- Wide Excisional Biopsy
- Mohs Micrographic Surgery
2 mins
Melanocytic Nevus (Mole)
- General Characteristics
- Benign Tumor of Melanocytes
- Arranged In Nests at Dermal-Epidermal Junction and Within Dermis
- Intradermal Nevi Are Papular and Flesh-Colored
- Junctional Nevi Are Macular and Dark
- Predisposing Factors
- Genetics
- Sun Exposure During Childhood
- Skin Tone
- Considerations
- Potential to Become Melanoma
- ABCDEs of Melanoma
4 mins
Acne Vulgaris Presentation and Pathophysiology
- Presentation
- Papules/Comedones in Mild Cases
- Blackheads Open, Whiteheads Closed
- Pustules in Mild-Moderate Cases
- Nodules/Cysts in Severe Cases
- Pathophysiology
- Inflammation at Hair Follicle/Sebaceous Gland
- Increased Androgens
- Colonization by Cutibacterium Acnes
3 mins
Tinea (Dermatophytes): General Characteristics And Management
- Fungal Cutaneous Infection
- Organisms
- Trichophyton
- Microsporum
- Epidermophyton
- Clinical Features
- Pruritic Rash
- Segmented Hyphae On KOH
- Management
- Topical Azole
- Terbinafine For Tinea Unguium (Nails)
2 mins
Kaposi Sarcoma
- Characteristics
- Malignant Vascular Tumor
- Human Herpesvirus Type 8 (HHV-8)
- AIDS/Immunocompromised
- CD4+ < 500
- Presentation
- Multifocal Purple Lesions
- Skin
- Mucous Membranes
- Visceral Organs
- Diagnosis
- Spindle-shaped Cells
- Management
- Observation
- Chemotherapy
- Treat Underlying Disorder
3 mins
Xeroderma Pigmentosum
- Pathophysiology
- Defective Nucleotide Excision Repair
- Pyrimidine Dimer Accumulation
- Autosomal Recessive
- Susceptible to UVA and UVB Rays
- Presentation
- Actinic Keratosis
- Neurodegeneration
- Photosensitivity
- Corneal Ulcers
- Hyperpigmented Lentigines
- Considerations
- Increased Risk of Skin Cancer
3 mins
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