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Microbiology | Medicine (MD/DO) School Study Aid


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Single-stranded Positive-sense RNA Viruses
17 Picmonics to Learn | 33 mins

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Dengue
Characteristics
RNA Virus
Flavivirus
SS Positive Linear
Transmitted by Aedes Mosquito
Tropical Regions
Classic Dengue Fever
Fever
Arthralgias and Myalgias
Maculopapular Rash
Retro-orbital Pain
Thrombocytopenia
Dengue Hemorrhagic Fever
Petechiae
Increased Capillary Permeability and Leakage
Hemorrhagic Shock
Diagnosis
Complete Blood Cell Count
Antibody Testing
Management
Supportive Care
Vaccination
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4 mins
Hepatitis C
Characteristics
Enveloped
RNA Virus
Flavivirus
Icosahedral
SS positive Linear
Clinical Features
Most Cases are Due to IV Drug Use
Turns to Chronic Hepatitis in Over 70% of Cases
Cirrhosis
Hepatocellular Carcinoma
Most Common Indication for Liver Transplantation
Associated With Type I MPGN
Porphyria Cutanea Tarda
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2 mins
Hepatitis C (HCV) Assessment
Transmission
Blood Transmission
High Risk Sex (rare)
IV Drug Abusers
Incubation
7 Weeks
Chronic Disease
Cirrhosis
Considerations
Barrier Protection
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2 mins
Yellow Fever Virus
Characteristics
Flavivirus
RNA Virus
Enveloped
Icosahedral
SS Positive Linear
Transmitted By Aedes Mosquitos
Monkey or Human Reservoir
Signs and Symptoms
High fever
Jaundice
Black vomitus
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2 mins
Coronavirus
Characteristics
RNA Virus
Enveloped
Helical
SS Positive Linear
Symptoms
Common Cold
SARS (Severe Acute Respiratory Syndrome)
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1 min
Norovirus
Characteristics
Calicivirus
RNA Virus
Non-enveloped
Icosahedral
SS Positive Linear
Symptoms
Acute Gastroenteritis
Treatment
Supportive Therapy
Considerations
Often found in Cruise Ships
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1 min
Human Immunodeficiency Virus (HIV) Assessment
Assessment
RNA Retrovirus
CD4+ Helper T Cells
Primary Infection
Flu-like Symptoms
Lymphadenopathy
Symptomatic Stage
Fatigue
Diarrhea
Unexplained Weight Loss
White Spots on Tongue
Persistent Fever
Night Sweats
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2 mins
Human Immunodeficiency Virus (HIV) Diagnosis
HIV-1/2 Antigen/Antibody Immunoassay
HIV-1/2 Antibody Differentiation Immunoassay
Nucleic Acid Testing (NAT)
Viral Load
Polymerase Chain Reaction (PCR) in Neonates
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3 mins
Human Immunodeficiency Virus (HIV) Stages
Primary Infection
Within 3 Weeks
Flu-like Symptoms
Asymptomatic Stage
Years
Symptomatic Stage
CD4+ < 500
AIDS
Opportunistic Infections
CD4+ < 200
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2 mins
Adult T Cell Lymphoma
Caused by HTLV 1
Japan, West Africa, Caribbean
Present with cutaneous lesions
Aggressive
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1 min
Rubella
Characteristics
RNA Virus
Togavirus
Enveloped
Icosahedral
SS Positive Linear
Signs and Symptoms
German Measles or Three-Day Measles
Fever
Postauricular Tenderness
Lymphadenopathy
Truncal Rash
Arthritis
Congenital TORCH Infection
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2 mins
Rubella TORCH
Signs and Symptoms
Nonspecific TORCH Symptoms
Patent Ductus Arteriosus
Pulmonary Artery Hypoplasia
Cataracts
Deafness
Blueberry Muffin Rash
Glaucoma
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1 min
Picornavirus
Characteristics
Non-enveloped
RNA Virus
Icosahedral
Positive Sense
A large polypeptide cleaved by proteases
Viruses
Rhinovirus
Poliovirus
Coxsackievirus
Hepatitis A Virus
Echovirus
Aseptic meningitis
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1 min
Coxsackievirus
Characteristics
Picornavirus
Signs and Symptoms
Coxsackie A
Febrile Pharyngitis
Hand, Foot, and Mouth Disease
Most Common Cause of Aseptic Meningitis
Late Summer
Coxsackie B
Myocarditis
Dilated Cardiomyopathy
Type 1 Diabetes
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2 mins
Rhinovirus
Picornavirus
Cause of Common Cold
More than 100 Serologic Types
Destroyed by Stomach Acid
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31 secs
Hepatitis A
Characteristics
Picornavirus
4 Week Incubation Period
Fecal-oral
Day Care Centers
Travel to Developing Countries
Signs and Symptoms
Usually Asymptomatic
Acute Disease
Jaundice
Fever
Vomiting
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2 mins
Poliomyelitis
Characteristics
Poliovirus
Picornavirus
Fecal-Oral Transmission
Destruction of Anterior Horn
Clinical Features
Flaccid Paralysis
Hyporeflexia
Fasciculations
Diagnosis
Elevated CSF Lymphocytes and Proteins
Normal CSF Glucose
Viral Culture or PCR
Management
Supportive Care
Vaccination
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3 mins

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