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Biochemistry is a subsection of science that brings together biology and chemistry, dealing with chemical processes that occur in the human body. This is typically seen as a harder subject to tackle in medical school, but erase your fears! No more waking up in cold sweats from a nightmarish biochemistry exam! This study guide presents those highly-tested biochemistry principles, key reactions, and associated disease states in an understandable and interesting format, allowing for maximum comprehension in the least amount of time to increase your retention for classes and the USMLE Step 1.

Biochemistry

Genetics & Genetic Disorders

Cystic Fibrosis Mechanisms

Autosomal Recessive

Which of the following best describes the manner by how a patient most likely acquires cystic fibrosis?

CFTR chromosome 7

Which of the following is most likely related to the genetic or chromosomal defect that causes cystic fibrosis?

Cl- channel defect

What is the most likely primary defect seen in patients with cystic fibrosis?

Decreased chloride secretion

The primary defect seen in cystic fibrosis most likely leads to which of the following subsequent problems?

Increased Na and water reabsorption

Which of the following pathophysiological processes is most associated with the lungs and GI tract of patients with cystic fibrosis?

Increased Na and Cl in sweat

Which of the following pathophysiologic processes is most related to the skin of patients with cystic fibrosis?

Dehydration of mucous layers

Which of the following pathological descriptions is most likely the result of cystic fibrosis?

Cystic Fibrosis Symptoms and Complications

Recurrent Pulmonary Infections

Which of the following is most likely to occur in patient with cystic fibrosis?

Chronic Bronchitis

Nasal Polyps

Which of the following is most likely to be seen in patient with cystic fibrosis?

Pancreatic Insufficiency

Intestinal Obstruction

Which of the following is most likely to be seen in newborns with cystic fibrosis?

Malabsorption and Diarrhea

Which of the following symptoms is prevalent among patients with cystic fibrosis?

Vitamin Deficiencies

Chronic Hepatic Disease

Infertility in Males

Cystic Fibrosis Diagnosis and Treatment

Diagnosis

Sweat Chloride Test &gt; 60 mmol/L

Which of the following tests is most likely associated with cystic fibrosis diagnosis?

Meconium Ileus

Which of the following is most likely associated with cystic fibrosis diagnosis?

Treatment

N-acetylcysteine

Which of the following medications is associated with cystic fibrosis treatment?

Antibiotic Prophylaxis

Which of the following drug classes is associated with cystic fibrosis treatment?

Pulmonary Maintenance

Which of the following interventions is associated with cystic fibrosis treatment?

Lung Transplant

Which of the following is most likely indicated in cystic fibrosis treatment?

Vitamin Replacement

Which of the following treatments is associated with cystic fibrosis treatment that can combat malabsorption and pancreatic insufficiency?

Pancreatin, Pancrelipase (Pancreatic Enzymes)

Mechanism

Pancreatic Enzymes

Which of the following best describes pancreatin and pancrelipase?

Indications

Cystic Fibrosis

Which of the following conditions is pancreatin and pancrelipase most likely indicated for?

Side Effects

GI Distress

Which of the following is most likely a side effect of pancreatin and pancrelipase administration?

Considerations

Inactivated by Gastric Acid

Which of the following considerations is most likely associated with pancreatin and pancrelipase?

24 Hour Fat Excretion

Which of the following tests in indicated in a patient taking pancreatin or pancrelipase?

Take with Every Meal and Snack

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Biochemistry | Medicine (MD/DO) School Study Aid

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