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Medicine (MD/DO)
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USMLE Step 2
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Multisystem & Miscellanea
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Temperature Regulation Disorders

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Multisystem & Miscellanea | Medicine (MD/DO) School Study Aid

Temperature Regulation Disorders
5 Picmonics to Learn | 12 mins
Stages of Hypothermia
Mild
32 to 35°C (90 to 95°F)
Shivering
Moderate
28 to 32°C (82 to 90°F)
Obvious Motor Impairment
Slowed Thinking
Severe
< 28°C (< 82°F)
Shivering Stops
Paradoxical Undressing
Arrhythmias
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3 mins
Hypothermia Interventions
Remove From Environment
Remove Wet Clothing
Passive Rewarming
Warm Clothing
Active Rewarming
Heated Blankets
Warm IV Solutions
Heated Oxygen
Warm Gastric Lavage
Considerations
Warm Trunk BEFORE Extremities
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2 mins
Malignant Hyperthermia
Inheritance
Autosomal-Dominant
Pathophysiology and causes
Ryanodine Receptor 1 Mutation
Inhaled Anesthetics
Succinylcholine
Symptoms
Autonomic Instability
Muscle Rigidity
Treatment
Dantrolene
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2 mins
Malignant Hyperthermia vs. Neuroleptic Malignant Syndrome vs. Serotonin Syndrome
Autonomic Instability
Muscle Rigidity
Malignant Hyperthermia
Ryanodine Receptor 1 Mutation
Inhaled Anesthetics
Succinylcholine
Dantrolene
Neuroleptic Malignant Syndrome
Antidopaminergic Medications
Hyporeflexia
Myoglobinuria
Dantrolene
Serotonin Syndrome
Serotonergic Medications
Hyperreflexia
Clonus
Cyproheptadine
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3 mins
Heat Stroke
TYPES
Exertional
Nonexertional
Characteristics
Inadequate Hypothalamic Thermoregulation
Body Temperature > 40° C (104° F)
Clinical Features
Cutaneous Calor and Rubor
Rhabdomyolysis
No Diaphoresis
CNS Changes
Acute Kidney Injury
Management
Rapid External Cooling
Hydration
Electrolyte Correction
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3 mins

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