Lee Shared "Endo-1" - 95 Picmonics
With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing. Whether you're studying for your classes or getting ready for a big exam, we're here to help.
Endo-1
Glycogen Metabolism
- Glycogenesis
- Glucose to UDP-Glucose
- Chain Elongation
- UDP-Glucose to Glycogen
- Glycogenin
- Glycogen Synthase
- Branching Enzyme
- Glycogenolysis
- Glycogen to Glucose
- Glycogen Phosphorylase + Vitamin B6 Cofactor
- Limit Dextrin
- Debranching Enzyme
4 mins
Glucagon (GlucaGen)
- Mechanism
- Increases Glucose
- Indications
- Hypoglycemic Emergency
- Side Effects
- Nausea and Vomiting
- Considerations
- Reconstitute Powder
- Consume Oral Carbohydrates
- 50% Dextrose IV (If No Effect)
2 mins
Gluconeogenesis
- OVERVIEW
- Produces Glucose from Non-Carbohydrate Substrates
- Upregulated by Glucagon and Cortisol
- PATHWAY
- Pyruvate
- Pyruvate Carboxylase
- Oxaloacetate
- Phosphoenolpyruvate (PEP) Carboxykinase
- Phosphoenolpyruvate (PEP)
- Fructose-1,6-bisphosphate
- Fructose-1,6-bisphosphatase
- Fructose-6-phosphate
- Glucose-6-phosphate
- Glucose 6-phosphatase
- Glucose
- Clinical Relevance
- Von Gierke Disease
4 mins
Cholesterol Synthesis
- Pathway
- Acetyl-CoA
- Acetoacetyl-CoA
- Cytosolic HMG-CoA Synthase
- HMG-CoA
- HMG-CoA Reductase
- Mevalonate
- Cholesterol
2 mins
Familial Hypercholesterolemia (Type IIa Familial Dyslipidemia)
- INHERITANCE
- Autosomal Dominant
- PATHOGENESIS
- Defective or Absent LDL Receptors
- Defective Apolipoprotein B-100 (ApoB-100)
- Lab Findings
- Increased LDL
- Decreased HDL
- Type IIb also has Increased VLDL
- Symptoms/Findings
- Accelerated Atherosclerosis
- Achilles Tendon Xanthomas
- Xanthelasma
- Corneal Arcus
4 mins
Hexose Monophosphate Shunt (Pentose Phosphate Pathway)
- Oxidative Phase (Irreversible)
- Glucose-6-Phosphate Dehydrogenase
- Converts Glucose-6-Phosphate to Ribulose-5-Phosphate
- Generates NADPH
- Reduces Glutathione
- Prevents Oxidative Damage
- Non-Oxidative Phase (Reversible)
- Ribulose-5-Phosphate to Ribose-5-Phosphate
- Nucleotide Synthesis
2 mins
Lipid Metabolism and Ketogenesis
- Lipid Metabolism
- Acetyl-CoA
- Biotin Cofactor
- Malonyl-CoA
- Fatty Acids
- Triglycerides
- Glycerol
- DHAP
- Acetoacetyl-CoA
- HMG-CoA
- HMG-CoA Reductase
- Mevalonate
- Cholesterol
- Ketogenesis
- Acetoacetate
- Beta-Hydroxybutyrate
4 mins
Lipogenesis
- Fatty Acid Synthesis
- Acetyl-CoA
- Citrate Shuttle to Cytoplasm
- Acetyl-CoA Carboxylase
- Biotin Cofactor
- Malonyl-CoA
- Fatty Acid Synthase
- Triglyceride Synthesis
- Glycerol
- Glycerol-3-Phosphate Acyltransferase
- Triglycerides
2 mins
Lipolysis
- Triglyceride Breakdown
- Triglycerides
- Hormone Sensitive Lipase
- Glycerol
- Fatty Acids
- Fatty Acid Transport
- Long-chain Fatty Acids
- Carnitine Shuttle
- Medium-chain and Short-chain Fatty Acids Diffuse Freely
- Fatty Acid Breakdown
- Beta Oxidation
- Acetyl-CoA if Even Number of Carbon Atoms
- Propionyl-CoA if Odd Number of Carbon Atoms
- Propionyl-CoA Carboxylase
- Biotin Cofactor
- Methylmalonyl-CoA
- Methylmalonyl-CoA Mutase
- Vitamin B12 Cofactor
- Succinyl-CoA
5 mins
Ethanol Metabolism
- Characteristics
- Zero Order Elimination
- Pathway
- Ethanol
- Alcohol Dehydrogenase
- Produces NADH
- Acetaldehyde
- Acetaldehyde Dehydrogenase
- Produces NADH
- Acetate
- Thiokinase
- Acetyl-CoA
- Drugs
- Fomepizole
- Disulfiram
3 mins
Abetalipoproteinemia
- Pathophysiology
- Autosomal Recessive
- Deficiency of Apolipoproteins B-48 and B-100
- MTTP Gene Mutation
- Clinical Features
- Malabsorption
- Steatorrhea
- Failure to Thrive
- Ataxia
- Retinitis Pigmentosa
- Spinocerebellar Degeneration
- Diagnosis
- Lipid-Laden Enterocytes
- Acanthocytes
- Decreased Cholesterol and LDL
- Treatment
- Vitamin E (Alpha-Tocopherol)
4 mins
Dysbetalipoproteinemia (Type III Familial Dyslipidemia)
- INHERITANCE
- Autosomal Recessive
- PATHOGENESIS
- Defective Apolipoprotein E (Apo E)
- Lab Findings
- Increased Chylomicrons
- Increased VLDL
- Symptoms/Findings
- Premature atherosclerosis
- Tuberoeruptive xanthomas
- Palmar xanthomas
3 mins
Hyperchylomicronemia (Type I Familial Dyslipidemia)
- INHERITANCE
- Autosomal Recessive
- PATHOGENESIS
- Lipoprotein Lipase Deficiency (LPL)
- Altered Apolipoprotein C-II (Apo C-II)
- Lab Findings
- Increased Chylomicrons
- Increased Cholesterol
- Increased Triglycerides
- Symptoms/Findings
- Pancreatitis
- Hepatosplenomegaly
- No Increased Risk for Atherosclerosis
- Eruptive/Pruritic Xanthomas
- Milky White Appearance of Blood When Drawn
3 mins
PCSK9-Inhibitors
- AVAILABLE DRUGS
- Evolocumab
- Alirocumab
- MECHANISM OF ACTION
- Monoclonal Antibodies
- Bind the PCSK9 Enzyme
- Decreased Degradation of LDL-receptors
- Increased LDL Receptors on Hepatocytes
- Reduction of LDL in Plasma
- INDICATION
- Second-line Therapy for Hypercholesterolemia
- ADMINISTRATION
- Subcutaneous Injection
- SIDE EFFECTS
- Skin Reaction at the Injection Site
- Myalgia
- Neurocognitive Impairment
2 mins
Thyroid Gland
- Characteristics
- TSH Stimulates T3 and T4 Release
- Metabolism Regulation
- Blood Calcium Sensor
- Calcitonin Release
- Blood Calcium Decreases
- Bone Building
2 mins
11 Beta-Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Signs and Symptoms
- Hypertension
- Masculinization
1 min
17 Alpha Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Sex Hormones
- Increased Mineralocorticoids (DOC)
- Hypertension
- Hypokalemia
- XY Externally Phenotypic Female
- No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
- XX Externally Phenotypic Female
- Sexual Infantilism
2 mins
21 Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Signs and Symptoms
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
2 mins
Acromegaly Assessment
- Mechanism
- Excess Growth Hormone (GH)
- Signs and Symptoms
- Protruding Jaw
- Large Lips and Nose
- Hearing Loss
- Enlargement of Hands and Feet
- Vision Changes and Headache
- Joint Pain
- Peripheral Neuropathy
- Hyperglycemia
2 mins
Addison's Disease
- Mechanism
- Chronic 1° Adrenal Insufficiency
- Atrophy
- Destruction
- Symptoms
- Deficiency In Cortisol And Aldosterone
- Skin Hyperpigmentation
- Increased POMC
- Hypotension
- Hyperkalemia
- Acidosis
- Addisonian Crisis
- Diagnosis
- ACTH (Cosyntropin) Stimulation Test
- Treatment
- Exogenous Cortisol
2 mins
Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:
Over 2,040,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.
Choose the #1 Medicine (MD/DO) student study app.
Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.
Works better than traditional Medicine (MD/DO) flashcards.
Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.