Alaine Shared "Block 6 Pharm 1" - 52 Picmonics
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Block 6 Pharm 1
Levothyroxine
- Indications
- Hypothyroidism
- Myxedema Coma
- Mechanism of Action
- Isomer of Thyroid Hormone (T4)
- T3 has Higher Potency
- Side Effects
- Hyperthyroid Symptoms
57 secs
Propylthiouracil (PTU) and Methimazole (MMI)
- Indications
- Hyperthyroidism
- Mechanism
- Inhibits Thyroid Peroxidase
- PTU Blocks Peripheral Conversion of T4 to T3
- Side Effects
- Agranulocytosis
- Skin Rash
- Hepatotoxicity (PTU)
- Teratogen (MMI)
1 min
Hyperthyroidism Interventions
- Drug Therapy
- Propylthiouracil (PTU)
- Methimazole (Tapazole)
- Iodine
- Beta Blockers
- Other Therapies
- Radioiodine Ablation
- Thyroidectomy
- Complications
- Thyrotoxicosis
- Post-Surgery Hypocalcemia
2 mins
Hypothyroidism Intervention
- Medications
- Levothyroxine (Synthroid)
- Liothyronine (Cytomel)
- Complication
- Myxedema Coma
- Nursing Considerations
- Lifelong Replacement Hormone
- Monitor Vital Signs
- Fluids and Fiber
- Low Calorie, Low Fat Diet
- Medication Education
- No Switching Brands
2 mins
Thyroid Storm
- Symptoms
- Diarrhea
- Liver Failure
- Insulin Resistance
- Tachycardia
- Lid lag
- Change in LOC (Altered Mental Status)
- High fever
- Treatment
- Propranolol (Or Esmolol)
- PTU (Thionamides) Initially
- Iodine Solution (Lugol Iodine)
- Glucocorticoids
- Cooling Blanket
3 mins
Amiodarone
- Mechanisms
- Class III Antiarrhythmic (K+ Channel Blocker)
- Decreases SA and AV Node Conduction
- Inhibits Cytochrome P450
- Indications
- Supraventricular Tachycardia with Heart Failure
- Ventricular Tachycardia
- Side Effects
- Hepatotoxicity
- Pulmonary Fibrosis
- Bradycardia
- Heart Block
- Thyroid Disorders
- Blue/Gray Skin Deposits
- Corneal Deposits
3 mins
Parkinson's Drugs
- Parkinsons Characteristics
- Decreased Dopamine
- Increased Acetylcholine
- Drug Names
- BALSA Acronym
- Bromocriptine
- Amantadine
- Levodopa
- Selegiline
- Antimuscarinics
2 mins
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
P450 Inhibitors
- Quinidine
- Ciprofloxacin
- Isoniazid
- Grapefruit Juice
- Acute Alcohol Use
- Erythromycin (Macrolide)
- Indinavir
- Cimetidine
- Sulfonamides
- Ketoconazole
- Amiodarone
2 mins
Acromegaly Assessment
- Mechanism
- Excess Growth Hormone (GH)
- Signs and Symptoms
- Protruding Jaw
- Large Lips and Nose
- Hearing Loss
- Enlargement of Hands and Feet
- Vision Changes and Headache
- Joint Pain
- Peripheral Neuropathy
- Hyperglycemia
2 mins
Addison's Disease
- Mechanism
- Chronic 1° Adrenal Insufficiency
- Atrophy
- Destruction
- Symptoms
- Deficiency In Cortisol And Aldosterone
- Skin Hyperpigmentation
- Increased POMC
- Hypotension
- Hyperkalemia
- Acidosis
- Addisonian Crisis
- Diagnosis
- ACTH (Cosyntropin) Stimulation Test
- Treatment
- Exogenous Cortisol
2 mins
Octreotide
- Indications
- Acute Variceal Bleeds
- Pituitary Tumors
- GH Secreting Tumors
- Carcinoid Tumors
- VIPoma
- Mechanism
- Somatostatin Analog
2 mins
Somatostatin
- Secreted by D Cells
- Pancreas
- GI Tract
- Action
- Decrease Secretion of Gastric Acid and Pepsinogen
- Decrease Pancreatic and Small Intestine Fluid Secretion
- Decrease Gallbladder Contraction
- Decrease Glucagon and Insulin Secretion
- Regulation
- Secretion is Increased by Acid
- Secretion is Decreased by Vagal Stimulation
- Clinical Use
- Octreotide
- Carcinoid Syndrome
- Variceal Bleeds
2 mins
Insulin
- Rapid Acting
- Insulin Lispro (Humalog)
- Insulin Aspart (Novolog)
- Insulin Glulisine (Apidra)
- Short Acting
- Regular Insulin (Humulin R)
- Intermediate Acting
- Isophane NPH (Humulin N)
- Long Acting
- Detemir (Levemir)
- Glargine (Lantus)
2 mins
Insulin Regulation
- Master Regulator
- Glucose
- Incretins Released with Oral Glucose
- GLP-1
- GIP
- Positive Regulators
- Beta-2 Receptor Stimulation
- M3 Acetylcholine Receptor Stimulation
- Negative Regulators
- Alpha-2 Receptor Stimulation
- Somatostatin
2 mins
Insulin Synthesis
- Synthesis
- Preproinsulin
- Rough Endoplasmic Reticulum
- Proinsulin
- Golgi Body
- Beta Cells Release Insulin
- Beta Cells Release C-peptide
- Clinical Relevance
- Insulinoma
- Sulfonylureas
- Surreptitious Insulin Use
2 mins
Pregnant Diabetic Patient Interventions
- First Trimester
- Increase Insulin then Decrease
- Metformin
- Nutrition
- Exercise
- Second Trimester
- Increase Insulin
- More Likely to Develop Hypoglycemia than Hyperglycemia
- Third Trimester
- Double or Quadruple Insulin
- Early Delivery
- Postpartum
- Drastically Decrease Insulin
- Monitor Neonate for Hypoglycemia
3 mins
Diabetes Interventions
- Early Diagnosis
- Insulin
- Oral Hypoglycemics
- Glucose Monitoring
- Routine Exercise
- Diabetic Diet
- Monitor for Complications
- Insulin Therapy
- Diabetic Ketoacidosis (DKA)
2 mins
Hyperglycemia
- Mechanism
- Insulin Resistance
- Too Little Insulin/Medication
- Infection/Illness
- Corticosteroids
- Assessment
- Elevated Blood Glucose
- Polyphagia
- Polydipsia
- Polyuria
- Hypotension
- Fatigue/Drowsiness
1 min
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