Chuck Shared "ID-CUMULATIVE-UMMS" - 133 Picmonics

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ID-CUMULATIVE-UMMS

1st Generation Cephalosporin
Drug Names
Cefazolin
Cephalexin
Indications (PEcK Mnemonic)
Proteus mirabilis
E. coli
Klebsiella
Gram-Positive Cocci
1 min
2nd Generation Cephalosporin
Drug Names
Cefoxitin
Cefaclor
Cefuroxime
Indications (PEcK HENS Mnemonic)
Proteus mirabilis
E. coli
Klebsiella
Gram-Positive Cocci
Haemophilus influenzae
Enterobacter
Neisseria
Serratia marcescens
2 mins
3rd Generation Cephalosporin
Drug Names
Cefotaxime
Ceftriaxone
Cefdinir
Ceftazidime
Pseudomonas
Indications
Serious Gram-Negative Bacteria Resistant to Other Beta-Lactams
1 min
4th Generation Cephalosporin
Drug Name
Cefepime
Indications
Increased Activity Against Gram-Positive Infections and Pseudomonas
29 secs
5th Generation Cephalosporin
Mechanism
Beta-Lactam
Indications
Resistant Bacteria
Broad Spectrum Gram-Positive and Gram-Negative
Drugs
Ceftobiprole
Has Pseudomonas Coverage
Ceftaroline
No Pseudomonas Coverage
1 min
Adenovirus
Characteristics
Non-enveloped
Icosahedral
Linear
Double Stranded DNA
Signs and Symptoms
Pharyngitis
Conjunctivitis
Fever
Summer Swimming
Day Care Centers
Acute Hemorrhagic Cystitis
Pneumonia
1 min
Aminoglycosides
Drug Names
Gentamicin
Neomycin for Bowel Surgery Prep
Amikacin
Tobramycin
Streptomycin
Mechanism of Action
Bactericidal
Inhibit Formation of Initiation Complex
Cause Misreading of mRNA
Require O2 for Uptake
Resistance
Resistance by Transferase Enzymes
Acetylation
Phosphorylation
Adenylation
Indications
Gram-Negative Rod Infections
Synergistic with B-Lactam Antibiotics
Side Effects
Nephrotoxicity Especially When Used with Cephalosporins
Ototoxicity Especially When Used with Loop Diuretics
Teratogen
5 mins
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
1 min
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
1 min
Aspergillus fumigatus
Characteristics
Fungi
Monomorphic
Septate Hyphae
Branch at Acute Angles
Fruiting Bodies
Disease
Allergic Bronchopulmonary Aspergillosis (ABPA)
Eosinophilia
Increased IgE
Glucocorticoids +/- Azoles
Pulmonary Aspergillosis
TB Cavity
Lung Aspergilloma
Hemoptysis
Invasive Aspergillosis
AIDS/Immunocompromised
Chronic Granulomatous Disease
Hemorrhagic Infarction
Necrotizing Bronchopneumonia
Voriconazole +/- Caspofungin
3 mins
Azoles (Ketoconazole)
"-azole" suffix
Indications
Local and Less Serious Systemic Mycosis
Mechanism
Inhibits Ergosterol Synthesis
Inhibits P450
Side Effects
Liver Dysfunction
Inhibition of Testosterone Synthesis
1 min
Bacteroides Fragilis
Characteristics
Gram-Negative
Anaerobe
Normal Colonic Flora
Produces Vitamin K
Produces Gas in Tissue
Foul-Smelling
Signs and Symptoms
Gastrointestinal Abscess
Treatment
Penicillin-Resistant
Clindamycin
Metronidazole
2 mins
Beta-Lactamase Inhibitors
Considerations
Often Combined with Penicillin Antibiotics
Drug Names
Clavulanic Acid
Sulbactam
Tazobactam
51 secs
Blastomyces
Characteristics
Fungi
Hyphae Form at 20°-25°C
Yeast Form at 37°C
Round Yeast
5-15 Micrometer (um or μm)
Single Broad-Based Buds
Thick Doubly-Refractive Walls
East of the Mississippi River and Around the Great Lakes
Signs and Symptoms
Pneumonia
Skin Infection
Bone Infection
Granulomatous Response
Treatment
Itraconazole
Amphotericin B
3 mins
Campylobacter Jejuni
Characteristics
Gram-Negative
Bacillus
Flagella
Curved
Corkscrew Appearance
Oxidase-Positive
Grows Well at 42 Degrees
Undercooked Poultry
Unpasteurized Milk
Puppies with Diarrhea
Signs and Symptoms
Bloody Diarrhea
Guillain-Barre syndrome
Reiter's Syndrome or Reactive Arthritis
3 mins
Candida Albicans
Fungi
Yeast with Pseudohyphae at 20 Degrees C
Germ Tube Formation at 37 Degrees C
Pruritic Vaginitis
White Cottage Cheese Discharge
Fiery Red Mucosa
Diabetics
Antibiotic Use
Esophageal Thrush in Immunocompromised
Diaper Rash
Endocarditis in IV Drug Users
2 mins
Cephalosporins Overview
Mechanism of Action
Beta lactam drug
Inhibits cell wall synthesis
Bactericidal
Side Effects
Hypersensitivity reactions
Vitamin K Deficiency
Disulfiram like reaction with Alcohol
Increased Nephrotoxicity of Aminoglycosides
1 min
Chlamydia trachomatis
Characteristics
A to C
Trachoma
Follicular Conjunctivitis
Blindness
Africa
L1 to 3
Lymphogranuloma venereum
Buboes
Genital Ulcer
D to K
Urethritis and PID
Neonatal Pneumonia
Staccato Cough
Neonatal Conjunctivitis
2 mins
Chloramphenicol
Mechanism
Bacteriostatic
Inhibits 50S Peptidyltransferase Activity
Indications
Meningitis
Rocky Mountain Spotted Fever in Pregnant Women
Side Effects
Anemia
Aplastic Anemia
Gray Baby Syndrome due to Decreased UDP-Glucuronyl Transferase
Resistance Caused by Plasmid Encoded Acetyltransferase
2 mins
Cidofovir
Indications
CMV Retinitis
Acyclovir-resistant HSV
Mechanism
Inhibits Viral DNA Polymerase
Side Effects
Nephrotoxicity
Administer with Probenecid and IV Saline
1 min

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