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PicmonicUserXAEA-Twelve Shared "6. Neurology & Psychiatry" - 284 Picmonics

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6. Neurology & Psychiatry

Tuberous Sclerosis
Characteristics
Autosomal Dominant
Signs and Symptoms
Hamartomas in CNS and Skin
Phakoma
Subependymal Giant Cell Astrocytoma
Seizures
Intellectual Disability (Mental Retardation)
Adenoma Sebaceum
Shagreen Patch
Ash-leaf Spots
Renal Angiomyolipoma
Cardiac Rhabdomyoma
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2 mins
Normal Pressure Hydrocephalus
Mechanism
Elderly
Idiopathic
Decreased Absorption of CSF
Ventricular Enlargement
Symptom Triad
Urinary Incontinence
Ataxia (Gait)
Cognitive Dysfunction
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2 mins
Ependymoma
Occur in Children
Fourth Ventricle
Hydrocephalus
Perivascular Pseudorosettes
Rod Shaped Blepharoplasts
Cauda Equina in Adults
Poor Prognosis
Neurofibromatosis Type II
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2 mins
Von Hippel-Lindau Disease
Pathophysiology
Chromosome 3
Presentation
Hemangioblastomas
Medulla, Retina, Cerebellum
Cysts
Kidney, Liver, Pancreas
Develop Bilateral Renal Carcinomas
Pheochromocytomas
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2 mins
Muscular Dystrophy
Mechanism
X-linked Recessive
Signs and Symptoms
Muscle Weakness
Motor Problems
Gower Sign
Large Calves
Waddling Gait
Loss of Ambulation
Consideration
Cardiac and Respiratory Failure
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2 mins
Myasthenia Gravis
Mechanism
Antibodies to Acetylcholine Receptor
Symptoms
Ptosis
Diplopia
Weakness with Muscle Use
Respiratory Death
Thymus Associated
Treatment
Acetylcholinesterase Inhibitors
Plasmapheresis
Thymectomy
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1 min
Lambert-Eaton Syndrome
Mechanism
Autoantibody to the Presynaptic Calcium Channel on Motor Neurons
Inhibits Acetylcholine (ACh) Release at Neuromuscular Junction
Paraneoplastic Syndrome
Small Cell Lung Cancer
Symptoms
Proximal Muscle Weakness
Improves with Muscle Use
Autonomic Symptoms
Extraocular Muscle Sparing
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2 mins
Nondepolarizing Neuromuscular Blocking Drugs
Names Include "Cur"
Competitive Antagonists
Acetylcholine Competition
Reversal of Blockade
Neostigmine, Edrophonium
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1 min
Indirect Cholinomimetics
Acetylcholinesterase Inhibitors
Doesn't Cross BBB
Edrophonium
Myasthenia Gravis (Diagnosis)
Pyridostigmine and Neostigmine
Myasthenia Gravis (Tx)
Ileus
Crosses BBB
Physostigmine
Atropine Overdose
Glaucoma
Donepezil
Alzheimer's
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2 mins
Closed-Angle Glaucoma
Primary
Lens causes pupillary obstruction
Aqueous humor builds behind iris
Iris bends forward, obstructing trabecular mesh
Secondary
Hypoxia Causes Neovascular Proliferation
Contraction and obstruction of trabecular mesh
Chronic disease (Crone)
Asymptomatic
Acute Disease
Eye pain and blindness
Rock-hard eye
Headache
Emergency
Epinephrine contraindicated
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2 mins
Open-Angle Glaucoma
Humor Has Access to Trabecular Meshwork
Presentation
Painless
African American
Elderly
Positive Family History
Primary Open-Angle Glaucoma
Most Common Form of Glaucoma
Unknown Mechanism
Secondary Open-Angle Glaucoma
Blocked Trabecular Meshwork (With Open-Angle)
WBCs
Red Blood Cells (RBC)
Retinal Products
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2 mins
Detached Retina
Assessment
Flashes of Light
Floaters
Curtain Like Shadow
Interventions
Eye Patch
Bed Rest
Surgical Emergency
Considerations
No Vigorous Activity
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2 mins
Cataract
Mechanism
Age-related
Assessment
No Pain
Cloudy Opaque Lens
Decreased Visual Acuity
Occurs Gradually
Treatment
Surgery
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1 min
Age-Related Macular Degeneration (AMD)
Mechanism
Dry (nonexudative)
Wet (exudative)
Signs and Symptoms
Scotomas
Blurred, Darkened Vision
Loss of Central Vision
Distortion of Vision
Considerations
Drug Therapy
Surgery
Low-vision Assistive Devices
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2 mins
Migraine Headaches Signs and Symptoms
Signs and Symptoms
More Common in Women
Exacerbated by Activity
Unilateral Pulsating Pain
Aura
Photophobia and Phonophobia
Nausea/Vomiting
Duration
4 hours to 3 Days
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1 min
Migraine Headache Treatments
Acute Treatment
Avoid Triggers
Sumatriptan
NSAIDs
Preventative Treatment
Beta Blockers
Calcium Channel Blockers
Amitriptyline
Topiramate (Anticonvulsants)
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1 min
Tension Headache
Presentation
More Common in Women
Bilateral Band-like Pain
Occipital and Neck region
Exacerbated by Stress
Exacerbated by Fatigue
Duration
> 30 Minutes
Acute Treatment
Relaxation
Caffeine
NSAIDs
Acetaminophen
Preventative Treatment
Amitriptyline
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1 min
Cluster Headache
Presentation
More Common in Men
Unilateral Periorbital Headache
Ipsilateral Tearing
Precipitated by Alcohol
Stabbing Pain
Duration
15 min - 3 Hours
Repetitive Attacks in Clusters
Treatment
High Flow 100% O2
Ergots
Sumatriptan
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2 mins
Sumatriptan
Mechanism of Action
Short Half-Life
5-HT Agonist
Inhibits Trigeminal Nerve Activation
Induces Vasoconstriction
Indications
Migraine
Cluster Headache
Side Effects
Increased Risk of Serotonin Syndrome
Paresthesias
Coronary Vasospasm
Contraindication
Prinzmetal's Angina
Coronary Artery Disease (CAD)
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3 mins
Opioids Overview
Indications
Pain
Weaning
Cough
Diarrhea
Mechanism of Action
Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
Decrease Synaptic Transmission
Side Effects
Respiratory Depression
Addiction
Miosis
Constipation
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2 mins

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