Honey Shared "PHARM TEST 2" - 78 Picmonics

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PHARM TEST 2

Selective Serotonin Reuptake Inhibitor (SSRI) Overview
Indications
Depression
Anxiety
Mechanism of Action
Selective Serotonin Reuptake Inhibitors
Drugs
Paroxetine
Sertraline
Escitalopram
Fluoxetine
Side Effects
Sexual Dysfunction
Serotonin Syndrome
Treat with Cyproheptadine
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2 mins
Buspirone
Indications
Generalized Anxiety
Mechanism of Action
Releases Dopamine and NE
Stimulates 5-HT1A receptors
Side Effects
Low Side Effect Profile
Safer with Alcohol than Other Anxiolytics
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1 min
Fluoxetine (Prozac)
Mechanism of Action
Inhibits Reuptake of Serotonin
Indications
Depression
Side Effects
Sexual Dysfunction
CNS Stimulation
Weight Changes
Serotonin Syndrome
Contraindications
No MAO-Is
No Anticoagulants / Antiplatelets
Considerations
Suicide Risk
Delayed Onset of Action
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2 mins
Monoamine Oxidase Inhibitor (MAOI) Contraindications
Contraindications
Wine and Cheese
Hypertensive Crisis
Serotonin Drugs
Serotonin Syndrome
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1 min
Lithium
Indications
Bipolar Disorder
Mechanism of Action
Mood Stabilizer
Unknown Mechanism
Side Effects
Nephrogenic Diabetes Insipidus
Hypothyroidism
Movement (Tremor)
Heart Block
Contraindication
Pregnancy (Ebstein's Anomaly)
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1 min
Tramadol
Indications
Chronic Pain
Mechanism of Action
Weak Opioid
Inhibit Serotonin and NE reuptake
Side Effect
Increased Risk of Seizure
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47 secs
Atypical Antipsychotics
Indications
Schizophrenia
Mechanism of Action
Unknown Mechanism
Side Effects
Seizures
Prolonged QT Interval
Agranulocytosis
Weight Gain
Fewer Extrapyramidal Side Effects
Fewer Anticholinergic Side Effects
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2 mins
Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Monoamine Oxidase Inhibitors (MAO-Is)
Indications
Atypical Depression
Mechanism of Action
Increase Levels of Amine Neurotransmitters
Drugs
"Takes Pride In Shanghai"
Tranylcypromine
Phenelzine
Isocarboxazid
Selegiline
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1 min
Tricyclic Antidepressants (TCAs) Indications
Indications
Major Depression
Bedwetting
Fibromyalgia
OCD
Drugs
-Iptyline or -Ipramine Suffix
Amitriptyline
Desipramine
Clomipramine
Imipramine
Nortriptyline
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2 mins
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Indications
Depression
Diabetic Peripheral Neuropathy
Duloxetine
Panic and Anxiety
Venlafaxine
Mechanism of Action
Inhibits Reuptake of Serotonin and NE
Side Effects
Hypertension
Insomnia
Nausea and Vomiting
Decreased Libido
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1 min
Carbamazepine
Indications
First-line Seizure Medication
First Line for Trigeminal Neuralgia
Mechanism of Action
Stabilizes Inactive State of Na+ Channels
Side Effects
Stevens-Johnson Syndrome
Induce Cytochrome P450
Teratogen
Hepatotoxicity
Blood Dyscrasias
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2 mins
Meperidine (Demerol)
Mechanism
Opioid Receptor Agonist
Indications
Moderate to Severe Pain
Post Anesthesia Shivering
Side Effects
Tremors
Constipation
CNS Depression
Sedation
Considerations
Short Term Administration
Increased Risk Serotonin Syndrome
Does NOT cause Miosis
Renal Failure Increases Toxicity Risk
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2 mins
High Potency Antipsychotic Drugs
High Potency Drugs
Fluphenazine
Trifluoperazine
Haloperidol
Side Effects
Extrapyramidal Symptoms
Short Term
Dystonia
Torticollis
Long Term
Tardive Dyskinesia
Parkinson's-like Symptoms
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1 min
Bipolar Disorder Interventions
Drug Therapy
Lithium
Valproic Acid (Valproate)
Lamotrigine
Manic Episode
Hospitalization
Nutrition
Hygiene
Depressive Episode
Monitor for Vegetative Signs
Suicide Precautions
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2 mins
Antipsychotics Overview
Indications
Schizophrenia
Tourette's Syndrome
Mechanism of Action
Lipid-Soluble
Block Dopamine Receptors
Side Effects
Galactorrhea
Tardive Dyskinesia
Anticholinergic
Alpha1 Antagonist
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2 mins
Tricyclic Antidepressants (TCAs) Overview
Mechanism of Action
Blocks Serotonin and NE Reuptake
Lipid-soluble
Side Effects
Adverse CNS Effects
Anticholinergic
Antihistamine
Tri-C: Convulsion, Coma, Cardiotoxicity
Blocks Alpha1 Receptors
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2 mins
Ondansetron
Indications
Postoperative Vomiting
Chemotherapy-induced Nausea and Vomiting
Mechanism
5-HT3 Serotonergic Antagonist
Centrally-acting Antiemetic
Side Effects
Headache
Constipation
QT Prolongation
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1 min
Metoclopramide
Indications
Antiemetic
Promotility Agent
Mechanism
Increased Resting Tone
Antagonist at D2 Receptor
Side Effects
Parkinsonian Symptoms
Galactorrhea
Contraindication
Small Bowel Obstruction
Parkinson's Disease
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2 mins
Haloperidol (Haldol)
Mechanism
High Potency Antipsychotic
Indications
Migraine
Schizophrenia
Side Effects
Extrapyramidal Symptoms
Weight Gain
QT Prolongation
Restlessness
Considerations
Caution in Seizure Patients
Neuroleptic Malignant Syndrome
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2 mins

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