Ken Shared "Pharm CNS 2.2" - 25 Picmonics

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Pharm CNS 2.2

Schizophrenia Assessment
Positive Symptoms
Hallucinations
Delusions
Associative Looseness
Negative Symptoms
Flat Affect
Poverty of Thought
Absence of Something that Should be Present
Cognitive Symptoms
Illogical Thinking
Impaired Judgment and Memory
Affective Symptoms
Dysphoria
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2 mins
Bipolar Disorder Assessment
Mechanism
Neurotransmitter Dysregulation and Genetic Factors
Mania Signs and Symptoms
Euphoric Mood
Nonstop Physical Activity
Flight of Ideas
Rapid Speech
Depression Signs and Symptoms
Mood Changes
Sad Affect
Psychomotor Retardation
Suicidal Thoughts
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2 mins
Tardive Dyskinesia
Signs and Symptoms
Bizarre Facial Movements
Bizarre Tongue Movement
Increased Extremity Movements
Stiff Neck
Dysphagia
Interventions
Stop Medication
AIMS
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2 mins
Neuroleptic Malignant Syndrome
FEVER Acronym
Fever
Encephalopathy
Vital Signs Unstable
Elevated Enzymes
Rigidity of muscles
Reversal Agent
D2 Agonists
Bromocriptine
Dantrolene
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2 mins
Alcohol withdrawal syndrome
Mild 6-24
Mild 6-24
tremors,
diaphoresis,
Insomnia
Palpitations
Anxiety
12-48
12-48
intact orientation
Tonic-Clonic Seizures
Benzodiazepines
Hallucination
48-96
48-96
Delirium tremens
Confusion,
agitation,
Fever
Tachycardia
hypertension,
Hallucinations
lorazepam
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2 mins
Alcohol withdrawal time line
Alcoholic of 5-15 years quits drinking
12-24 hours- Alcoholic hallucinosis
Delerium Tremens usually begin within 48-96 hours and can last 1-5 days
Delerium Tremens presentation
DT- once again visual and tactile hallucinations
Tachycardia
hypertension
Fever
agitation or lethargy
Dilated eyes
Diaphoresis
Acute Treatment
Benzodiazepines "Pam-Lam's" used to treat Delerium Tremens.
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Delirium Tremens
TIMING
2-4 Days After Last Drink
Cause
Alcohol Withdrawal
Clinical Manifestations
Altered Mental Status (Change In LOC)
Anxiety
Hallucinations
Autonomic Instability
Seizures
Insomnia
Nausea/Vomiting
Treatment
Benzodiazepines
Supportive Care
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3 mins
Alcohol and benzodiazepines withdrawl
examination
Seizures
Tachycardia
Palpitations
symptoms
benzodiazepines
Tremors
Anxiety
Perceptual Distortion
Psychosis
Insomnia
alcohol
Delirium
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Delirium Tremens
Life-threatening alcohol withdrawal syndrome that peaks 2–4 days after last drink
Classically occurs in hospital setting (eg, 2–4 days postsurgery) in alcoholics not able to drink as inpatients
Characterized by autonomic hyperactivity (eg, tachycardia, tremors, anxiety, seizures)
Alcoholic hallucinosis
Treatment
Use Chlordiazepoxide if patient shows no sign of liver disease
If patients shows sign of liver disease use: Oxazepam, Temazepam and Lorazepam
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Hypnotic Benzodiazapines
azopam or azolam ending
Hypnotics
Estazolam (Prosom)
Prosom
Flurazepam (Dalmane)
Dalmane
Quazepam (Doral)
Doral
Triazolam (Halcion)
Halcion
Temazepam (Restoril)
Restoril
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Short-acting Benzodiazepines
Characteristics
Short Acting
High Addiction Potential
Drug Names
Alprazolam
Triazolam
Oxazepam
Midazolam
Mnemonic
ATOM
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Buspirone
Indications
Generalized Anxiety
Mechanism of Action
Releases Dopamine and NE
Stimulates 5-HT1A receptors
Side Effects
Low Side Effect Profile
Safer with Alcohol than Other Anxiolytics
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1 min
Bipolar Disorder Interventions
Drug Therapy
Lithium
Valproic Acid (Valproate)
Lamotrigine
Manic Episode
Hospitalization
Nutrition
Hygiene
Depressive Episode
Monitor for Vegetative Signs
Suicide Precautions
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2 mins
Barbiturates (Specific)
Methohexital
Anesthesia Induction
Phenobarbital
Secobarbital
Sedation and Insomnia
Pentobarbital
Seizure
Coma
Short to Long Acting
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Carbamazepine
Indications
First-line Seizure Medication
First Line for Trigeminal Neuralgia
Mechanism of Action
Stabilizes Inactive State of Na+ Channels
Side Effects
Stevens-Johnson Syndrome
Induce Cytochrome P450
Teratogen
Hepatotoxicity
Blood Dyscrasias
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2 mins
Wernicke-Korsakoff Syndrome
Thiamine deficiency
Confusion
Ophthalmoplegia
Ataxia
Korsakoff
Confabulation
Personality Changes
Memory loss
Alcoholics
Damage to medial dorsal nucleus
Damage to mammillary bodies
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2 mins
Cocaine Intoxication Assessment
Euphoria
Delusions
Mydriasis
Hallucinations
Agitation
Hypertension
Arrhythmias
Hyperthermia
Seizures
Nasal Septum Perforation
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2 mins
Amphetamines Intoxication Assessment
Euphoria
Insomnia
Mydriasis
Diaphoresis
Hypertension
Tachycardia
Paranoia
Anxiety
Anorexia
Seizures
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2 mins
Suvorexant
Orexin/Hypocretin Receptor Antagonist
Indications: Insomnia
SFx: URT Infection, Abnml. Dreams, HA, Dizziness
Contraindications: Narcolepsy, CYP3A4 Inhibitors
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Triptans
Bioavailability
Delivery Options
Drugs
Sumatriptan
Almotriptan
Naratriptan
Rizatriptan (Maxalt)
Eletriptan (Relpax)
Zolmitriptan
Frovatriptan
Contraindications
No MAO-Is
Increased Risk Serotonin Syndrome
Angina Contraindication
HTN contraindication
Mnemonic
Story (Part 1)
Story (Part 2)
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