James Shared "Pharm Exam 2: Cholinergic and Adrenergic" - 41 Picmonics

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Pharm Exam 2: Cholinergic and Adrenergic

Direct Cholinomimetics
Muscarinic agonists
Bethanechol
Bladder and Bowels
Methacholine
Bronchoconstriction
Pilocarpine
Contracts ciliary muscle and pupillary sphincter
Carbachol
Releases intraocular pressure
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1 min
Indirect Cholinomimetics
Acetylcholinesterase Inhibitors
Doesn't Cross BBB
Edrophonium
Myasthenia Gravis (Diagnosis)
Pyridostigmine and Neostigmine
Myasthenia Gravis (Tx)
Ileus
Crosses BBB
Physostigmine
Atropine Overdose
Glaucoma
Donepezil
Alzheimer's
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2 mins
Anticholinergics
B.O.AT.S Acronym
Benztropine
Parkinson's Disease
Oxybutynin
Decrease bladder spasms
Atropine
Mydriasis and Cycloplegia
Scopolamine
Motion Sickness
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1 min
Anticholinergics Continued
Drugs
Glycopyrrolate
Reduces Airway Secretions
Ulcer Treatment
Ipratropium
Asthma and C.O.P.D
Dicyclomine
Hyoscyamine
Irritable Bowel Syndrome
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1 min
Nondepolarizing Neuromuscular Blocking Drugs
Names Include "Cur"
Competitive Antagonists
Acetylcholine Competition
Reversal of Blockade
Neostigmine, Edrophonium
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1 min
Acetylcholinesterase Inhibitor Antidote
Antidote
Atropine
Pralidoxime
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59 secs
Acetylcholinesterase Inhibitor Poisoning
DUMBBELSS
Diarrhea
Urination
Miosis
Bronchospasm
Bradycardia
Emesis
Lacrimation
Salivation
Sweating
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2 mins
Sjögren’s Syndrome
Mechanism
Autoimmune Exocrine Gland Destruction
Symptoms (Classic Triad)
Xerostomia
Xerophthalmia
Arthritis
Diagnosis
Anti SS-B (La)
Anti SS-A (Ro)
Schirmer's Test
Salivary Gland Biopsy
Treatment
Symptomatic Treatment
Complications
Lymphoma
Other
Sicca Syndrome
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4 mins
Antimuscarinic Antidote
Antidote
Physostigmine Salicylate
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44 secs
Donepezil
Indications
Alzheimer's Disease
Mechanism of Action
Acetylcholinesterase Inhibitor
Increased Acetylcholine
Side Effects
Nausea and Vomiting
Dizziness
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51 secs
Atropine
Indications
Blocks DUMBBeLSS
Bradycardia
Side Effects
Skin Flushing
Increased Temperature
Dry Mouth
Cycloplegia
Disorientation
Mydriasis
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1 min
Succinylcholine
Indications
Inducing Paralysis
Mechanism of Action
Neuromuscular Blocking Drugs
Motor Nicotinic Receptor
ACh Receptor Agonist
Depolarization
Phases of Action
Phase I (Paralysis Non-reversible)
Phase II (Paralysis Reversible)
Neostigmine (Reversal Agent)
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2 mins
CNS Stimulants
Indications
Attention Deficit Hyperactivity Disorder (ADHD)
Obesity
Mechanism of Action
Increase Catecholamines at Synaptic Cleft
Increase Norepinephrine
Increase Dopamine
Drug Names
Methylphenidate (Ritalin)
Methamphetamine
Side Effect
Potential for Abuse
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56 secs
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
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1 min
Alpha 2 Receptor
Characteristics
Gi Subunit
Decrease Sympathetic Outflow
Decrease Insulin Release
Decrease Lipolysis
Increase Platelet Aggregation
Decrease Aqueous Humor Production
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2 mins
Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
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1 min
Alpha-2 Agonists (Sympathoplegics)
Indications
Hypertension
Renal disease
Mechanism of Action
Centrally acting Alpha-2 Agonist
Drugs
Clonidine
Rebound Hypertension
Alpha-Methyldopa
Pregnancy
Coombs (+) Hemolytic Anemia
SLE Like Syndrome
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2 mins
Dobutamine
Mechanism
Beta-1 Agonist
Inotropic
Indications
Heart Failure
Side Effects
Tachycardia
Arrhythmias
Considerations
Closely Monitor Patients
Other Meds May Increase Potency
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1 min
Epinephrine
Mechanism of Action
Alpha Agonist
Beta Agonist
Indications
Hypotension
Anaphylaxis
Allergy
Glaucoma
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44 secs
Norepinephrine
Mechanism of Action
Alpha Agonist
Beta1 Agonist
Indications
Hypotension
Side Effect
Decreases Renal Blood Flow
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1 min

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