Professor Bibin Shared "The Cellular Adaptation" - 12 Picmonics
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The Cellular Adaptation
- Voltage-Gated Calcium Channels Open
- Ca2+ Influx
- Vesicle-Membrane Fusion
- Exocytosis of Neurotransmitter
- Neurotransmitter Binds Post-Synaptic Receptors
- Neurotransmitter Breakdown
- Neurotransmitter Reuptake
- Characteristics
- Cardiac and Smooth Muscle Location
- Fast Transmission
- Bidirectional
- Presynaptic Na+ Floods Through Gap Junction
- Na+ Influx Initiates Postsynaptic Action Potential
- Characteristics
- More Na+ Outside
- Sodium-Potassium Pump
- K+ Leaks Out
- More K+ Inside
- About -70mV
- Voltage-Gated Sodium Channels are Closed
- Characteristics
- Summation of Signals
- -50 mV Threshold Value Reached
- Voltage-Gated Sodium Channels Open
- Local Depolarization
- Na+ Influx
- Potassium Channels open
- Repolarization
- Characteristics
- Unidirectional Depolarization
- Absolute Refractory Period In Preceding Na+ Channels
- Neighboring Voltage Gate Channels Open
- Nodes of Ranvier
- Myelination Increases Propagation Speed
- Saltatory Conduction
- Changes in Mood
- Poor Hygiene
- Odd Sleep Patterns
- Frequent Injuries
- Relationship or Job Difficulty
- Poor Performance
- Anorexia OR Weight Loss
- Social Isolation
- Financial Problems
- Abuse Assessment
- Euphoria
- Miosis
- CNS Depression
- Abuse Withdrawal
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Consideration
- Naloxone
- Antidote
- Naloxone
- Euphoria
- Slowed Reaction Time
- Conjunctival Injection
- Increased Appetite
- Anxiety
- Social Withdrawal
- Paranoid Delusions
- Euphoria
- Delusions
- Mydriasis
- Hallucinations
- Agitation
- Hypertension
- Arrhythmias
- Hyperthermia
- Seizures
- Nasal Septum Perforation
- Intoxication
- CNS Depression
- Withdrawal
- Wernicke-Korsakoff Syndrome
- Medical Complications
- GI Distress
- Cardiomyopathy
- Pancreatitis
- Cirrhosis
- Immunosuppression
- Sexual Dysfunction
- Considerations
- Screening (Assessments)
- Withdrawal
- Reduce Environmental Stimuli
- Antianxiety Medications
- Vitamin Supplements
- Seizure Precautions
- Suicide Precautions
- Fever
- Considerations
- Identify Support Systems
- Group Therapy
- Disulfiram
- Naltrexone
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