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GI
Staphylococcus aureus Disease
Skin Infections
Impetigo
Abscesses
Exfoliative Toxin
Scalded Skin Syndrome
Toxic Shock Syndrome (TSST 1)
Binds to MHC II and T Cell Receptor
Food Poisoning
Acute Bacterial Endocarditis
Pneumonia
Osteomyelitis
2 mins
Staphylococcus aureus Characteristics
Characteristics
Gram-Positive
Cocci
Catalase-Positive
Coagulase-Positive
Beta-Hemolytic
Protein A Virulence Factor
Inhibits Phagocytosis
MRSA
Resistant to Beta Lactams Due to Altered Penicillin Binding Proteins (PBPs)
2 mins
Bacillus Cereus Disease
Signs and Symptoms
Emetic Form
Short Incubation (1-6 Hours)
Nausea and Vomiting
Diarrheal Form
Long Incubation (8-16 Hours)
Diarrhea and GI Pain
2 mins
Bacillus Cereus Characteristics
Gram-Positive
Bacilli
Endospore Forming
B Hemolytic
Toxins and Enterotoxins
Reheated Rice
1 min
Vibrio Cholera Characteristics
Gram-Negative
Bacilli
Glucose Fermenting
Non-lactose Fermenting
Oxidase Positive
Comma Shaped
Thrives in Alkaline Environment
Crustaceans
1 min
Vibrio Cholera Disease
ADP Ribosylating AB Toxin
Turn Gs on Causing Increase in cAMP
Secretion of Cl
Blocks Reabsorption of Na
Rice Water Diarrhea
1 min
Clostridium perfringens
Characteristics
Gram-Positive
Bacillus
Anaerobe
Spore-Forming
Alpha Toxin Lecithinase
Phospholipase
Heat Labile Enterotoxin
Signs and Symptoms
Myonecrosis
Gas Gangrene
Food Poisoning and Diarrhea
Treatment
Hyperbaric O2 Chamber
2 mins
Giardia lamblia
Characteristics
Protozoa
Ingestion of Cysts
Seen in Campers
Daycare Centers
Mental Hospitals
Infects Small Intestine
Signs and Symptoms
Bloating
Flatulence
Fatty Diarrhea
Diagnosis
Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
Predisposed if Low IgA
Treatment
Metronidazole
3 mins
Cryptosporidium
Characteristics
Protozoa
Ingestion of Oocysts in Food or Water
Acid Fast Cysts
Signs and Symptoms
Outbreaks of Diarrhea from Contaminated Water Supply
Mild Disease in Non-immunocompromised
Severe Diarrhea in AIDS
Treatment
Nitazoxanide for Immunocompetent
2 mins
Entamoeba histolytica
Pathophysiology
Protozoa
Amebiasis
Ingestion of Cysts in Food and Water
Signs and Symptoms
Bloody Diarrhea
Flask-Shaped Ulcer
Liver Abscess
Anchovy Paste
RUQ Pain
Diagnosis
RBCs in Cytoplasm of Trophozoite
Cyst With Four Nuclei
Treatment
Metronidazole
Iodoquinol
3 mins
Rotavirus
Characteristics
Reovirus
Non-enveloped
Double-Stranded
RNA Virus
Linear
11 Segments
Triple Icosahedral Capsid
Most Common Cause of Diarrhea Worldwide
Villous Atrophy
Winter Months
Day Care Centers
Treatment
Oral Rehydration
2 mins
Norovirus
Characteristics
Calicivirus
RNA Virus
Non-enveloped
Icosahedral
SS Positive Linear
Symptoms
Acute Gastroenteritis
Treatment
Supportive Therapy
Considerations
Often found in Cruise Ships
1 min
Shigella
Characteristics
Gram-Negative
Bacilli
Non Lactose Fermenting
White on Macconkey Agar
Oxidase Negative
Non H2S Producing
Day Care Centers
High Virulence
Replicates Intracellularly
Actin Rocket
Signs and Symptoms
Bloody Diarrhea
Shiga Toxin
Inhibits 60S Ribosome
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Thrombocytopenia
Kidney Failure
3 mins
Salmonella Enterica Spp.
Characteristics
Animal and Human Reservoir
Poultry and Eggs
Turtles
PMN Immune Response
Symptoms
Gastroenteritis
Diarrhea
Possibly Bloody
Treatments
No Antibiotics
No Vaccine Available
2 mins
Salmonella Typhi
Characteristics
Colonizes Gallbladder
Monocytic Immune Response
Symptoms
Typhoid Fever
Abdominal Pain
Rose Spots on Abdomen
Constipation Followed by Diarrhea
Treatments
Ceftriaxone
Fluoroquinolones
Considerations
Oral Vaccine - Live
IM Vaccine - Capsular Polysaccharide
2 mins
Campylobacter jejuni
Characteristics
Gram-Negative
Bacillus
Flagella
Curved
Corkscrew Appearance
Oxidase-Positive
Grows Well at 42 Degrees
Undercooked Meat
Unpasteurized Milk
Animals with Diarrhea
Signs and Symptoms
Bloody Diarrhea
Guillain-Barre syndrome
Reactive Arthritis
3 mins
Yersinia Enterocolitica
Characteristics
Gram-Negative
Bacilli
Non-lactose Fermenting
Non-H2S Producing
Oxidase-Negative
Day Care Centers
Pork
Raw Milk
Pet (Puppy) Feces
Signs and Symptoms
Bloody Diarrhea
Mesenteric Adenitis
Granulomatous Microabscess in Mesenteric Lymph Nodes
Pseudoappendicitis (Mimics)
Reactive Arthritis
2 mins
Enterohemorrhagic E. Coli (EHEC)
Characteristics
O157:H7
Non-Sorbitol Fermenting
Hamburger Meat
Produces Shiga-like Toxin
Gram-negative
Lysogeny
Inactivates 60S Ribosome
Disease
Bloody Diarrhea
Hemolytic Uremic Syndrome (HUS)
Hemolytic Anemia
Acute Renal Failure
Thrombocytopenia
2 mins
Helicobacter Pylori
Characteristics
Gram-Negative
Bacilli
Curved
Polar Flagellum
Catalase-Positive
Oxidase-Positive
Disease
Gastric and Duodenal Ulcers
Ammonia
Neutral Environment
Gastric Adenocarcinoma
MALT lymphoma
Diagnosis
Serology IgG antibody
Stool Antigen
Urease Positive Breath Test
Biopsy
Treatment
2 ABX and PPI
2 mins
Helicobacter pylori Associations
Gastritis
Peptic Ulcer Disease
Stomach Cancer
50 secs
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