United States University Faculty Shared "USU: MSN 571 WEEK 2" - 50 Picmonics
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USU: MSN 571 WEEK 2
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
- Abuse Assessment
- Euphoria
- Miosis
- CNS Depression
- Abuse Withdrawal
- Yawning
- Gooseflesh
- Sweating
- Rhinorrhea
- Kicking Movements
- Consideration
- Naloxone
1 min
Codeine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Mild to Moderate Pain
- Cough Suppressant
- Side Effects
- Sedation
- Constipation
- Miosis
- Considerations
- Close Monitoring When Breast Feeding
- Often Combined with Non-Opioids
2 mins
Morphine
- Mechanism
- Opioid Receptor Agonist
- Indications
- Pain
- Myocardial Infarction
- Side Effects
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension
2 mins
Oxycodone
- Mechanism of Action
- Opioid Receptor Agonist
- Indication
- Refractory Pain
- Side Effects
- Respiratory Depression
- Constipation
- CNS Depression
- Considerations
- Addiction
- Naloxone
2 mins
Acetaminophen-Hydrocodone (Vicodin)
- Mechanism of Action
- Combination Analgesic
- Opioid Receptor Agonist
- Hydrocodone
- Reversible Inhibition of COX
- Acetaminophen
- Indication
- Moderate to Severe Pain
- Side Effects
- CNS Depression
- Respiratory Depression
- Hepatotoxicity
- Considerations
- Addiction
2 mins
Meperidine (Demerol)
- Mechanism
- Opioid Receptor Agonist
- Indications
- Moderate to Severe Pain
- Post Anesthesia Shivering
- Side Effects
- Tremors
- Constipation
- CNS Depression
- Sedation
- Considerations
- Short Term Administration
- Increased Risk Serotonin Syndrome
- Does NOT cause Miosis
- Renal Failure Increases Toxicity Risk
2 mins
Local Anesthetic Overview
- Indications
- Minor Procedures
- Epidurals
- Mechanism of Action
- Blocks Na+ Channels
- State Dependent
- Combined with Vasoconstrictors
- Infected Tissue Requires Higher Dose
- Drugs
- Esters
- Amides
- Side Effects
- Arrhythmias
- Cardiotoxicity
1 min
Inhaled Anesthetics
- Mechanism of Action
- Unknown Mechanism
- Inhaled Anesthetic Drugs
- HEISMN Drug Name Acronym
- Side Effects
- Respiratory Depression
- Myocardial Depression
- Lower Metabolic Demand, Increased Cerebral Blood Flow
- Hepatotoxicity (Halothane)
- Nephrotoxicity (Methoxyflurane)
- Seizure (Enflurane)
- Malignant Hyperthermia
- Expansion of Trapped Gas
2 mins
IV Anesthetics
- Barbiturates
- Benzodiazepines
- Respiratory Depression
- Hypotension
- Ketamine
- NMDA Receptor Antagonist
- Hallucinations
- Opioids
- Propofol
- Potentiates GABA-A
2 mins
Lidocaine
- Mechanism
- Blocks Na+ Channels
- Indications
- Ventricular Arrhythmia
- Anesthetic
- Side Effects
- Paresthesias
- Seizures
- Respiratory Depression
- Drowsiness
- Consideration
- Anesthetic Effects Extended with Epinephrine
1 min
Bleomycin
- Indications
- Testicular Cancer
- Hodgkin's Lymphoma
- Mechanism of Action
- Induces Free Radical Formation
- Breaks in DNA Strands
- Side Effects
- Pulmonary Fibrosis
- Skin Changes
- Mucositis
1 min
Cyclophosphamide
- Mechanism
- Requires Bioactivation by Liver
- Cross-links DNA
- Guanine N7 Position
- Indications
- Autoimmune Disorders
- Leukemia
- Lymphoma
- Solid Tumors
- Side Effects
- Myelosuppression
- Hemorrhagic Cystitis
- Prevent with Mesna
3 mins
Dactinomycin (Actinomycin D)
- Indications
- Wilms' Tumor
- Rhabdomyosarcoma
- Ewing's Sarcoma
- Gestational Trophoblastic Malignancy
- Mechanism
- Intercalates DNA
- Side Effect
- Myelosuppression
1 min
Fluorouracil (5-FU)
- Mechanism
- Antimetabolite
- "Thymine-less Death"
- Indications
- Slow-growing Solid Tumors
- Co-administered with Leucovorin for Stomach Cancer
- Basal Cell Carcinoma (Topical)
- Side Effects
- Myelosuppression
- Mucositis
- Severe Diarrhea
3 mins
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Aromatase Inhibitors
- Indications
- Estrogen Receptor-positive (ER+) Breast Tumors
- Systemic Metastases
- Drugs
- Reversible, non-steroid
- Letrozole
- Anastrozole
- Irreversible, steroid
- Exemestane
- Side Effects
- Osteoporosis
- Arthritis
1 min
Rituximab
- Indications
- Chronic Lymphocytic Leukemia (CLL)
- Non-Hodgkin Lymphoma
- Rheumatoid Arthritis
- Microscopic Polyangiitis (MPA)
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Mechanism
- Monoclonal Antibody Against CD20
- Found on B Cell Neoplasms
- Side Effects
- Infusion Reactions
- Skin and Mouth Reactions
- Reactivation of Hepatitis B Virus (HBV)
- Progressive Multifocal Leukoencephalopathy (PML)
3 mins
Trastuzumab
- Indications
- HER-2+ Breast Cancer
- Stomach Cancer
- Mechanism
- Monoclonal Antibody Against HER-2
- Inhibition of Cellular Signaling
- Cytotoxicity
- Side effects
- Cardiotoxicity
1 min
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
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