Lperkowitz2892968 Shared "Derm Exam 2" - 35 Picmonics

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Derm Exam 2

Mycobacterium leprae
Aerobic
Acid Fast
Likes Cool Temperature
Tuberculoid leprosy
Granulomatous response
Positive Lepromin Skin Test
Dapsone
Rifampin
Lepromatous leprosy
Weak Immune System
Leonine facies
Negative Lepromin Skin Test
Clofazimine
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2 mins
Chronic Mucocutaneous Candidiasis
Mechanism and Characteristics
T Cell Dysfunction
Candida Albicans
Signs and Symptoms
Infections of Skin
Infections of Mucous Membrane
Susceptible to HPV Infections like Condyloma Acuminatum
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42 secs
Sporothrix Schenckii
Characteristics
Fungi
Thermally Dimorphic
Cigar-shaped Yeast Forms
Rose Thorn Prick
Packaging Peat Moss
Signs & Symptoms
Local Pustule or Ulcer
Nodules on Draining Lymphatics
Treatment
Potassium Iodide
Itraconazole
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2 mins
Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
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1 min
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
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1 min
Nystatin
Indications
Candidiasis
Vaginal
Oral
Cutaneous
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
Topical form of Amphotericin B
Side Effects
Rash
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1 min
Azoles (Ketoconazole)
"-azole" suffix
Indications
Local and Less Serious Systemic Mycosis
Mechanism
Inhibits Ergosterol Synthesis
Inhibits P450
Side Effects
Liver Dysfunction
Inhibition of Testosterone Synthesis
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1 min
Echinocandins
"-Fungin" suffix
Indications
Invasive Aspergillosis
Candida
Mechanism
Inhibits Cell Wall Synthesis
Inhibits Synthesis of Beta-glucan
Side Effects
GI Distress
Flushing
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1 min
Flucytosine
Indications
Cryptococcus
Candida
Used in Combination with Amphotericin B or Azoles
Mechanism
Inhibits DNA and RNA Synthesis
Converted to 5-FU by Cytosine Deaminase
Side Effects
Bone Marrow Suppression
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1 min
Terbinafine
Indications
Dermatophytosis
Onychomycosis
Mechanism
Inhibits Squalene Epoxidase
Side Effects
Hepatotoxicity
GI Distress
Taste Disturbances
Headache
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2 mins
Griseofulvin
Mechanism
Disrupts Microtubules in Mitosis
Indications
Antifungal for Superficial Infections
Tinea and Ringworm
Side Effects
Teratogen
P450 Inducer
Confusion
Headache
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2 mins
Rifampin
Tuberculosis (TB)
Blocks RNA Polymerization
Haemophilus influenzae Type B
Leprosy
Meningitis
P450 inducer
Red-orange urine
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55 secs
Rickettsia
Need CoA and NAD
Rocky Mountain spotted fever
Typhus
Ehrlichiosis
Q fever
Arthropod vector
Fever
Headache
Rash
Weil-Felix reaction
Treatment doxycycline
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1 min
Rocky Mountain Spotted Fever
Rickettsia rickettsii
Dermacentor Wood Tick
Endemic to East Coast
Fever
Headache
Rash Starts on Wrist and Ankle
Migrates towards trunk
Thrombocytopenia
Hyponatremia
Elevated liver enzymes
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59 secs
Borrelia burgdorferi
Characteristics
Lyme Disease
Spirochete
Dark-field Microscopy
Giemsa Stain
Silver Stain
White-footed Mouse
Ixodes Tick
Babesia
Anaplasmosis
Signs & Symptoms
Flu-like Symptoms
Erythema Migrans
Bulls Eye Rash
Bilateral Bell's Palsy
Conduction Defects
Arthropathy
Treatments
Doxycycline
Ceftriaxone
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3 mins
Bartonella henselae
Characteristics
Gram-Negative
Pleomorphic
Bacillus
Signs and Symptoms
Cat Scratch Fever
Lymphadenopathy
Bacillary Angiomatosis
Patients with AIDS
Mimics Kaposi Sarcoma
Benign
Reactive Arthritis
Non-Caseating Granuloma
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2 mins
Leishmania donovani
Pathophysiology
Protozoan
Visceral Leishmaniasis
Hepatosplenomegaly
Spiking Fevers
Skin Pigmentation
Sandfly
Diagnosis
Macrophages with Amastigotes
Treatment
Amphotericin B
Oral Miltefosine
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2 mins
Schistosoma
Pathophysiology
Trematode (Fluke)
Snail-infested Water
Intense Immune Response
Intestinal Disease
Hepatosplenic Granuloma
Squamous Cell Cancer of the Bladder
Diagnosis
Parasitic Antigens via ELISA
Treatment
Praziquantel
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2 mins
Melanoma Mechanism and Characteristics
Mechanism
Associated with Sunlight Exposure
Mutation in B-RAF kinase
Large Number of Moles
Fair-Skinned people at higher risk
Growth Phases
Radial Growth Phase
No Metastasis
Vertical Growth Phase
Depth of tumor correlates with risk of metastasis
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1 min
Melanoma Diagnosis
Signs
ABCDE Mnemonic
Asymmetry
Border irregularity
Color variation
Diameter > 6mm
Evolution over time
Diagnosis
S-100 Tumor Marker
LDH (Lactate Dehydrogenase) Screens for Metastasis
Treatment
Wide Local Excision
Adjuvant Therapy
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1 min

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