Sumana Shared "immuno" - 220 Picmonics
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immuno
Wiskott Aldrich
- Pathophysiology
- X-linked Recessive
- WASp Protein Mutation
- Antigen Presentation Defect
- Progressive Deletion of B and T Cells
- Signs and Symptoms
- Thrombocytopenia
- Eczema
- Infections
- Decreased IgM
- Increased IgE, IgA
2 mins
Sjögren’s Syndrome
- Mechanism
- Autoimmune Exocrine Gland Destruction
- Symptoms (Classic Triad)
- Xerostomia
- Xerophthalmia
- Arthritis
- Diagnosis
- Anti SS-B (La)
- Anti SS-A (Ro)
- Schirmer's Test
- Salivary Gland Biopsy
- Treatment
- Symptomatic Treatment
- Complications
- Lymphoma
- Other
- Sicca Syndrome
4 mins
Severe Combined Immunodeficiency (SCID)
- Both B and T Cell Deficiency
- Recurrent Viral, Bacterial, Fungal, Protozoal Infections
- Defective Interleukin (IL) 2 Receptor
- X-Linked
- Adenosine Deaminase Deficiency
- Failure to Synthesize MHC II Antigens
- Treat with Bone Marrow Transplant
2 mins
Selective IgA Deficiency
- Pathophysiology
- Defect in Class Switching
- Decreased IgA
- Signs and Symptoms
- Often Asymptomatic
- Increase in Atopic & Autoimmune Diseases
- Sinopulmonary Infections
- Increased Risk Giardia Lamblia Infections
- Inflammatory Bowel Disease
- Celiac Disease
- Considerations
- Anaphylaxis From IgA Containing Blood Products
2 mins
Leukocyte Adhesion Deficiency
- Pathophysiology
- Autosomal Recessive
- Integrin CD18 Protein
- Defect in LFA-1
- Attached to ICAM
- Signs and Symptoms
- Neutrophilia
- Bacterial Infections
- Non-Pyogenic
- Delayed Separation of Umbilical Cord
2 mins
Common Variable Immunodeficiency
- Pathophysiology
- Defect in B Cell Maturation
- Decreased Plasma Cells
- Decreased Immunoglobulins
- Signs & Symptoms
- Sinopulmonary Infections
- Increased Risk of Autoimmune Disease
- Lymphoma
1 min
Chronic Mucocutaneous Candidiasis
- Mechanism and Characteristics
- T Cell Dysfunction
- Candida Albicans
- Signs and Symptoms
- Infections of Skin
- Infections of Mucous Membrane
- Susceptible to HPV Infections like Condyloma Acuminatum
42 secs
Chediak-Higashi Syndrome
- Pathophysiology
- Autosomal Recessive
- Defective Lysosomal Trafficking Regulator Gene (LYST)
- Defect In Microtubular Function
- Decrease In Phagocytosis
- Signs And Symptoms
- Recurrent Pyogenic Infections
- Staph Aureus And Streptococci
- Partial Albinism
- Peripheral Neuropathy
- Pancytopenia
- Diagnosis
- Giant Granules In Granulocytes And Platelets
2 mins
Bruton's Agammaglobulinemia
- Pathophysiology
- X-linked Recessive
- Defective Bruton Tyrosine Kinase
- Blocks B Cell Maturation
- Signs & Symptoms
- Decreased Immunoglobulins of All Classes
- Bacterial Infections After Six Months
- Maternal IgG Protects Before Six Months
2 mins
Ataxia Telangiectasia
- Pathophysiology
- Autosomal Recessive
- ATM Gene
- Defect in DNA repair
- Signs & Symptoms
- Cerebellar defects
- Spider Angiomas
- Sensitive to Radiation
- Defective Tumor Suppressor Gene
- Increased risk of Cancer, Leukemias, and Lymphomas
- Increased AFP levels
- IgA deficiency
- Repeated sinopulmonary infections
2 mins
Mycoplasma Pneumoniae
- Characteristics
- No Cell Wall and No Gram Stain
- Cholesterol Membrane
- Eaton's Agar
- Mulberry Colonies
- Disease
- Atypical pneumonia
- Military Recruits
- Cold IgM Autoimmune Hemolytic Anemia
- Erythema Multiforme
- Treatment
- Tetracycline
- Erythromycin
2 mins
Gardnerella vaginalis
- Signs and Symptoms
- Bacterial Vaginosis
- Not an STD
- Fishy Smell
- Whiff Test
- Grey Vaginal Discharge
- Increase pH
- Clue Cells
- Squamous Epithelial Cells Covered with Bacteria
- Mobiluncus Coinfection
- Treatment
- Metronidazole
2 mins
Legionella Disease
- Signs and Symptoms
- High Fever
- Diarrhea
- Increased Liver Enzymes
- Hyponatremia
- Type IV Renal Tubular Acidosis
- Severe Atypical Pneumonia
- Pontiac Fever
- Treatment
- Fluoroquinolones
- Macrolides
2 mins
Legionella Characteristics
- Characteristics
- Bacillus
- Poor Gram Stain
- Charcoal Yeast with Iron and Cysteine
- Silver Stain
- Water Sources
- Smokers and Heavy Drinkers
- Detect Antigen in Urine
2 mins
Haemophilus ducreyi
- Characteristics
- Gram-Negative
- Coccobacillus
- Pleomorphic
- Parallel Short Chains
- School of Fish Appearance on Gram Stain
- Signs and Symptoms
- Chancroid
- Painful Genital Ulcer
- Buboes
- Treatment
- Azithromycin
- Ceftriaxone
2 mins
Bacteroides Fragilis
- Characteristics
- Gram-Negative
- Anaerobe
- Normal Colonic Flora
- Produces Vitamin K
- Produces Gas in Tissue
- Foul-Smelling
- Signs and Symptoms
- Gastrointestinal Abscess
- Treatment
- Penicillin-Resistant
- Clindamycin
- Metronidazole
2 mins
Brucella
- Characteristics
- Gram-Negative
- Coccobacillus
- Unpasteurized milk
- Goat cheese
- Inside macrophages
- Signs and Symptoms
- Lymphadenopathy
- Granulomas
- Undulating fever
- Treatment
- Doxycycline
- Gentamicin
2 mins
Bordetella pertussis
- Pathophysiology
- Gram-Negative
- Coccobacillus
- Bordet-Gengou Agar
- ADP Ribosylating AB Toxin
- Inhibits Gi to cause Increase in cAMP
- Signs AND Symptoms
- Lymphocytosis
- Increase in Insulin
- Catarrhal Phase is Infectious Period
- Paroxysmal Phase is Symptomatic Period
- Whooping Cough
- Treatment
- Macrolides
4 mins
Borrelia burgdorferi
- Characteristics
- Lyme Disease
- Spirochete
- Dark-field Microscopy
- Giemsa Stain
- Silver Stain
- White-footed Mouse
- Ixodes Tick
- Babesia
- Anaplasmosis
- Signs & Symptoms
- Flu-like Symptoms
- Erythema Migrans
- Bulls Eye Rash
- Bilateral Bell's Palsy
- Conduction Defects
- Arthropathy
- Treatments
- Doxycycline
- Ceftriaxone
3 mins
Chlamydia Characteristics
- Characteristics
- Cannot Make ATP
- Elementary body infects
- Intraepithelial
- Reticulate Body Replicates
- Diagnosis
- Cell Wall Lacks Muramic Acid
- Giemsa Stain
- Inclusion Bodies
- Treatment
- Azithromycin (Preferred)
- Doxycycline
2 mins
