Tyler Shared "HODI - week 8 - exams" - 33 Picmonics
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HODI - week 8 - exams
TNF-Alpha Inhibitor Drugs and Complications
- Etanercept
- Decoy TNF- Alpha receptor
- Anti-TNF- Alpha antibody
- Adalimumab
- Infliximab
- Complications
- Increased risk of infection
- Predispose to Tuberculosis (TB) reactivation
- Order Baseline PPD- skin test
- Quantiferon Gold In-Tube
- Order Chest X-Ray
2 mins
TNF-Alpha Inhibitors Overview
- Mechanism
- Downregulates Pro-inflammatory Cytokines
- Decreased Lymphocyte Activation and Migration
- Granuloma Breakdown
- Treats
- Crohn's Disease
- Rheumatoid Arthritis
- Juvenile Rheumatoid Arthritis
- Psoriasis
- Ankylosing Spondylitis
1 min
Azathioprine (Imuran)
- Mechanism
- Antimetabolite
- Prodrug of 6-mercaptopurine (6-MP)
- Inhibits Synthesis of Nucleic Acids
- Indications
- Autoimmune Disorders
- Kidney Transplantation
- Side Effects
- Myelosuppression
- Increased Toxicity with Allopurinol Use
- Pancreatitis
- Malignancy
3 mins
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Sulfa Drug Allergies
- Sulfasalazine
- Sulfonylureas
- Thiazide Diuretics
- Acetazolamide
- Furosemide Diuretic
- Celecoxib
- Probenecid
49 secs
Meckel's Diverticulum
- Pathophysiology
- True Diverticulum
- Vitelline Duct
- Yolk Stalk
- Contain Ectopic Tissue
- Pancreatic And Gastric Mucosa
- Signs and Symptoms
- Hemorrhage
- Intussusceptions
- Volvulus
- Diagnosis
- 2 Feet From Ileocecal Valve
- 2 Inches Long
- 2% Population
- First 2 Years Of Life
- Pertechnetate T99
2 mins
Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
- Characteristics
- Autosomal Dominant
- Defective DNA Mismatch Repair
- 80% Risk of Colon Cancer Development
- Proximal (Right) Colon
- Type II associated with Endometrial, Ovarian and Skin Cancers
- 3-2-1 Rule
- 3 Relatives with Colon Cancer
- Occurs Across 2 Generations
- 1 Relative Diagnosed < 50 Years Old
- Treatment
- Frequent Screening
- Colectomy
3 mins
Entamoeba histolytica
- Pathophysiology
- Protozoa
- Amebiasis
- Ingestion of Cysts in Food and Water
- Signs and Symptoms
- Bloody Diarrhea
- Flask-Shaped Ulcer
- Liver Abscess
- Anchovy Paste
- RUQ Pain
- Diagnosis
- RBCs in Cytoplasm of Trophozoite
- Cyst With Four Nuclei
- Treatment
- Metronidazole
- Iodoquinol
3 mins
Mallory-Weiss
- Characteristics
- Bleeding From Tears in Mucosa
- Forceful Vomiting
- Alcoholism
- Eating Disorders (Bulimia)
- Painful Hematemesis
- Diagnosis
- Endoscopy
- Management
- Observation
2 mins
Barrett's Esophagus
- Histological findings
- Metaplasia in Lower Esophagus
- Columnar Epithelium
- Associated Pathologies
- Gastroesophageal Reflux Disease (GERD)
- Esophagitis
- Esophageal Ulcers
- Increased Risk of Esophageal Adenocarcinoma
1 min
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Hypertrophic Pyloric Stenosis (HPS) Assessment
- Mechanism
- Hypertrophied Pylorus
- Risk Factor
- Macrolide Use
- Assessment
- 3-6 Weeks of Age
- Projectile Vomiting After Feeding
- No Pain or Discomfort
- Weight Loss
- Dehydration
- Hungry Baby
- Olive Mass
2 mins
Hypertrophic Pyloric Stenosis (HPS) Interventions
- Treatment
- Pyloromyotomy
- Preoperative Care
- Stabilize Fluid and Electrolyte Balance
- Nasogastric Tube
- Monitor Feeding
- Postoperative Care
- Start Formula or Breastfeeding Within 24 Hours
- Feedings Every 4-6 hours
- Full Feeding Within 2 days
2 mins
Small Intestine Absorption
- Characteristics
- Carbohydrates Undergo Active Transport
- Amino Acids Undergo Active Transport
- Small Lipids Undergo Passive Diffusion
- Epithelial Cells
- Intestinal Capillaries
- Hepatic Portal Transports Nutrients
- Liver
- Large Lipids Transported as Chylomicrons
- Lacteals Transport Chylomicrons
2 mins
Small Intestine Digestion
- Brush border enzymes
- Pancreatic Enzymes are secreted via a Duct
- Pancreas secretes bicarbonate
- Brush Border activates Pancreatic Trypsin
- Trypsin activates Chymotrypsin
- Trypsin and Chymotrypsin digest Proteins
- Gallbladder Releases Bile
- Pancreatic Lipase breaks down Lipids
- Goblet cells secrete mucus
- Pancreatic Amylase breaks down Carbohydrates
- Pancreatic Nucleases breakdown DNA/RNA
- Digestion occurs in the Duodenum
2 mins
Diverticulosis and Diverticulitis Assessment
- Diverticulosis
- Outpouching
- Diverticulitis
- Inflamed Diverticula
- Assessment
- Abdominal Pain
- Abdominal Distention
- Flatulence
- Fever
- Rectal Bleeding
- Alternating Constipation and Diarrhea
- Considerations
- Peritonitis
2 mins
Diverticulosis and Diverticulitis Interventions
- Interventions
- High Fiber Diet
- Reduce Intra-abdominal Pressure
- Stool Softeners
- Exercise
- Anticholinergics
- Considerations
- Antibiotics
- Bowel Resection
2 mins
Zollinger-Ellison Syndrome Disease
- Pathophysiology
- Gastrin-Secreting Tumor
- Increased Gastric Acid
- Recurrent Peptic Ulcers
- MEN Type 1
- Symptoms
- Abdominal Pain
- Heartburn (Pyrosis)
- Diarrhea
3 mins
Zollinger-Ellison Syndrome Diagnosis and Treatment
- Diagnosis
- Gastrin > 1000 pg/mL
- Positive Secretin Stimulation Test
- Treatment
- High-Dose PPI
- Octreotide
- Surgical Resection
3 mins
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