Elizette Shared "Nervous Final" - 26 Picmonics
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Nervous Final
Friedreich's Ataxia
- Trinucleotide Repeat
- GAA Repeat
- Frataxin
- Mitochondrial Dysfunction
- Autosomal Recessive
- Hammertoes
- High Arches
- Kyphoscoliosis
- Lateral Corticospinal Tract
- Posterior Column
- Spinocerebellar Tract
- Type I Diabetes Mellitus
- Hypertrophic Cardiomyopathy
1 min
Amyotrophic Lateral Sclerosis (ALS)
- Assessment
- Progressive Muscle Weakness
- Systemic Muscle Wasting
- Fasciculations
- Spasticity
- Fatigue
- Considerations
- Riluzole (Rilutek)
- Stretching
- Little to No Cognitive Decline
- Respiratory Support
- Palliative Care
2 mins
Type I Spinal Muscular Atrophy
- Pathophysiology
- Lower Motor Neuron Disease
- SMN1 Mutation
- Degeneration of Anterior Horn Cells
- Autosomal Recessive
- Clinical Features
- Symmetric Flaccid Paralysis
- Hypotonia
- Bulbar Palsy
- Extraocular Muscle Sparing
- Respiratory Failure
- Diagnosis
- Genetic Testing
- Treatment
- Supportive Therapy
- Nusinersen
3 mins
Parkinson's Disease Interventions
- Medications
- Levodopa/Carbidopa (Sinemet)
- Entacapone (Comtan)
- Selegiline (Eldepryl)
- Amantadine (Symmetrel)
- Bromocriptine (Parlodel)
- Benztropine (Cogentin)
- Considerations
- Allow Extra Time
- Ensure Patient Safety
- Surgery As Last Resort
2 mins
Parkinson's Disease Assessment
- Assessment
- Decreased Dopamine
- Older Adult
- Cogwheel Rigidity
- Bradykinesia
- Shuffling Gait
- Resting Tremor
- Pill-Rolling
- Mask-Like Face
- Cognitive Decline
2 mins
Lewy Body Dementia
- Pathophysiology
- Unknown Etiology
- Decreased Acetylcholine
- Alpha-synuclein Defect
- Eosinophilic Cytoplasmic Inclusion
- Signs and Symptoms
- Visual Hallucinations
- Progressive Dementia
- Fluctuating Cognition
- REM Sleep Behavior Disorder
- Parkinsonism
- Treatment
- Acetylcholinesterase Inhibitors
3 mins
Causes of Dementia
- Reversible Causes
- Intoxication or Medications
- Depression
- Normal Pressure Hydrocephalus
- Vitamin B12 Deficiency
- Metabolic Conditions
- Irreversible Causes
- Lewy Body Dementia
- Prion Disease
- Pick's Disease
- AIDS Dementia
- Alzheimer's Disease
- Multi-infarct (Vascular) Dementia
2 mins
Alzheimer's Disease Assessment (Early Symptoms)
- Risk Factors
- Advanced Age
- Early Signs and Symptoms
- Poor Judgment and Decision-Making
- Difficulty Having a Conversation
- Inability to Manage a Budget
- Losing Track of the Date or Season
- Misplacing Things
1 min
Alzheimer's Disease Assessment (Late Symptoms)
- Late Signs and Symptoms
- Memory Impairment
- Wandering Behavior
- Confabulation
- Perseveration
- Lack of Abstract Thinking
- Severe Cognitive Decline
1 min
5 A's of Alzheimer's Disease
- Agnosia
- Anomia
- Aphasia
- Apraxia
- Amnesia
1 min
Multiple Sclerosis Features and Mechanisms
- Features
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Mechanism
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
2 mins
Multiple Sclerosis Symptoms and Diagnosis
- Symptoms
- Optic Neuritis
- Internuclear Ophthalmoplegia
- Scanning Speech
- Urinary and Fecal Incontinence
- Motor Issues (Intention Tremor, Paresis)
- Numbness and Pain
- Depression
- Relapsing Symptoms
- Diagnosis
- Gold Standard = Plaques on MRI
- Increased CSF Immunoglobulins (IgG)
- Oligoclonal Bands
4 mins
Huntington's Disease Assessment and Interventions
- Assessment
- Decreased GABA
- Appears around Age 40
- Slow Cognitive Decline
- Choreiform Movements
- Non Repetitive Jerks
- Interventions
- Neuroleptics
- Tetrabenazine
- Genetic Counseling
- Considerations
- Stages of Disease
- High Calorie Diet
2 mins
Myotonic Dystrophy
- Pathophysiology
- Autosomal Dominant
- Trinucleotide Repeat
- CTG
- Signs and Symptoms
- Facial Muscle Weakness
- Frontal Balding
- Sustained Grip
- Conduction Defects
- Cataracts
- Selective Atrophy of Type 1 Fibers
- Testicular Atrophy
2 mins
Ataxia Telangiectasia
- Pathophysiology
- Autosomal Recessive
- ATM Gene
- Defect in DNA repair
- Signs & Symptoms
- Cerebellar defects
- Spider Angiomas
- Sensitive to Radiation
- Defective Tumor Suppressor Gene
- Increased risk of Cancer, Leukemias, and Lymphomas
- Increased AFP levels
- IgA deficiency
- Repeated sinopulmonary infections
2 mins
Restless Legs Syndrome
- Pathophysiology
- Idiopathic
- Iron Deficiency
- Parkinson's Disease
- Signs and Symptoms
- Urge to Move the Legs
- Unpleasant Sensations in Legs
- Worsens with Inactivity
- Relieved by Movement
- Treatment
- Iron Supplementation
- Self-care
- Gabapentin
- Pramipexole
2 mins
Fragile X
- Pathophysiology
- Trinucleotide Repeat
- CGG Repeats
- FMR1 Gene
- X-linked Dominant
- Signs and Symptoms
- Developmental Delay
- Autism
- Large Ears
- Large Jaw
- Long Face
- Macroorchidism
2 mins
Krabbe Disease
- Pathophysiology
- Autosomal Recessive
- Galactocerebrosidase Deficiency
- Increased Psychosine
- Signs and Symptoms
- Developmental Delay
- Peripheral Neuropathy
- Optic Atrophy
- Diagnosis
- Globoid Cells
1 min
Metachromatic Leukodystrophy
- Pathophysiology
- Autosomal Recessive
- Arylsulfatase A Deficiency
- Increased Cerebroside Sulfate
- Signs and Symptoms
- Demyelination
- Ataxia
- Dementia
1 min
Charcot Marie Tooth Disease
- Pathophysiology
- Hereditary Motor Sensory Neuropathy
- Autosomal Dominant
- PMP22 Duplication
- Schwann Cell Dysfunction
- Clinical Features
- Distal Muscle Weakness
- Foot Drop
- Calf Muscle Atrophy
- Scoliosis
- Hammertoes
- Pes Cavus
- Diagnosis
- Onion-skin Appearance on Nerve Biopsy
- Electrodiagnostic Studies
5 mins
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