Jordan Shared "Repro" - 36 Picmonics

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Repro

5 Alpha Reductase Deficiency
Autosomal Recessive
Inability to Convert Testosterone to DHT
Normal Internal Genitalia
Ambiguous External Genitalia until Puberty
Masculinization During Puberty with Growth of External Genitalia
LH can be Increased
Normal Estrogen, LH, and Testosterone levels
2 mins
Androgen Insensitivity (Complete)
Defect in androgen receptor
Phenotypically female
(46, XY)
Female external genitalia
Rudimentary Vagina
Scant sexual hair
Testes often in labia majora
Testes surgically removed to prevent malignancy
Increased estrogen, testosterone, and LH
Absent uterus and fallopian tubes
3 mins
Branchial Pouches: 1st Pouch
Endoderm Lines the Auditory Tube
Middle Ear Cavity
Eustachian Tube
Mastoid Air Cells
1 min
Branchial Pouches: 2nd Pouch
Palatine Tonsils
37 secs
Branchial Pouches: 3rd Pouch
Separates into Dorsal and Ventral Wings
Dorsal Wings
Inferior Parathyroid Glands
Ventral Wings
Thymus
1 min
Branchial Pouches: 4th Pouch
Separates into Dorsal and Ventral Wings
Dorsal Wings
Superior Parathyroid Glands
Ventral Wings
Parafollicular (C) Cells of Thyroid Gland
Formed by Neural Crest Cells
1 min
Brenner Tumor
Pathophysiology
Non-germ cell tumor
Transitional epithelium
Benign and unilateral
Coffee bean nuclei
2 mins
Choriocarcinoma
Germ-cell tumor
Trophoblastic tissue
Hematogenous spread to lungs
Malignant
Theca-lutein cysts
Hydatidiform Mole
hCG
59 secs
Ovarian Cystadenocarcinoma
Non-germ Cell Tumor
Mucinous
Peritoneal Spread
Serous
Psammoma Bodies
Bilateral
Malignant
Stromal Invasion
CA 125
BRCA-1 and Lynch Syndrome
1 min
Ovarian Cystadenoma
Non-germ cell tumor
Serous
Unilocular
Bilateral
Mucinous
Multilocular
Benign
Most Common
48 secs
Dysgerminoma
Germ-cell tumor
Most Common Malignant Germ Cell Tumor
Uniform Cells
Fried Egg Cells
hCG
LDH
Seminoma-like
Turner Syndrome
2 mins
Endometriosis Characteristics
Endometrial Tissue Outside of Uterus
Glands and Stroma
Most Common in Ovary, Pelvis, Peritoneum and Bowels
"Chocolate Cyst" in Ovary
Adenomyosis
Theories
Retrograde Flow
Metaplastic Transformation
Mullerianosis
1 min
Endometriosis Symptoms and Treatment
Symptoms
Dysmenorrhea
Cyclic Pelvic Pain
Dyschezia
Dysuria
Dyspareunia
30-40% are Infertile
Treatment
Surgery
NSAIDs
OCPs
Progesterone (Progestins)
GnRH Agonists
1 min
Fibroadenoma
Most Common Benign Breast Tumor
Stromal Tumor
Presentation
Women under 40
Small, firm mass
Sharp Edges
Increased tenderness and size with Estrogen
Management
Biopsy
1 min
Fibromas
Non-germ cell tumor
Meigs Syndrome
Thecoma
Pulling sensation in groin
Spindle-shaped fibroblasts
44 secs
Granulosa Cell Tumor
Granulosa Cells
Non-germ cell tumor
Endometrial Carcinoma
Call-Exner bodies
Estrogen producing
Precocious Puberty
42 secs
Intraductal Papilloma
Presentation
Bloody nipple discharge
Women 20-40 years old
Mechanism
Small tumor in lactiferous ducts
Occurs Centrally
Occurs Peripherally
Increased malignancy
Diagnosis
Too Small to Palpate
Galactogram biopsy
1 min
Kallman Syndrome
Mutation in KAL-1 or FGFR-1 Gene
Failure of GnRH Secreting Neurons
Delayed Puberty
Anosmia
Hypogonadism
Infertility
2 mins
Klinefelter's Syndrome
Pathophysiology
Male (XXY)
Signs and Symptoms
Eunuchoid Body Shape
Gynecomastia and Female Hair Distribution
Testicular Atrophy
Dysgenesis of Seminiferous Tubules
Possible Developmental Delay
Hypogonadism
Decreased Inhibin B
Increased FSH
Abnormal Leydig Cell Function
Decreased Testosterone
Increased LH
Increased Estrogen
Barr body (inactivated X chromosome)
6 mins
Krukenberg Tumor
Non-germ Cell Tumor
Lymphatic Spread to Ovaries
Metastasis
GI Malignancy
Mucin-secreting Signet Cell
34 secs

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