Jen Shared "New Picmonics" - 96 Picmonics

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New Picmonics

Gilbert's Syndrome
Pathophysiology
Decreased UDP-Glucuronosyltransferase Activity
Decreased Bilirubin Conjugation
Signs and Symptoms
Often Asymptomatic
Jaundice (Mild)
Fasting
Stress
Alcohol Intake
Labs
Increased Unconjugated Bilirubin
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2 mins
Stevens-Johnson Syndrome
Etiologies
Drugs
Symptoms
< 10% of Body Surface Area (BSA) Involved
10-30% BSA Overlaps with Toxic Epidermal Necrolysis (TEN)
Fever
Affects Skin and Mucous Membranes
Bullae Formation
Necrosis
Sloughing of Skin
High Mortality Rate
Treatment
Supportive Care
IVIG (Intravenous Immunoglobulin)
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3 mins
Ethacrynic Acid
Mechanism of Action
Non-sulfa Drug
Phenoxyacetic Acid Derivative
Loop Diuretic
Inhibits Na+-K+-2Cl- Cotransporter
Thick Ascending Loop of Henle
Clinical Use
Diuresis
Side Effects
Hypokalemia
Ototoxicity
Gout
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2 mins
NNRTI Drug Names
Nevirapine (Viramune)
Rilpivirine (Edurant)
Delavirdine (DLV, Rescriptor)
Efavirenz (EFV, Sustiva)
Etravirine (ETR, Intelence)
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54 secs
Bernard-Soulier Syndrome
Mechanism
Autosomal Recessive
Deficiency of Glycoprotein Ib (GpIb) Receptor
Symptoms
Mucosal Membrane Bleeding
Menorrhagia
Easy Bruising
Labs
Large Platelets
Increased Bleeding Time
No Platelet Agglutination with Ristocetin
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3 mins
Fluorouracil (5-FU)
Mechanism
Antimetabolite
"Thymine-less Death"
Indications
Slow-growing Solid Tumors
Co-administered with Leucovorin for Stomach Cancer
Basal Cell Carcinoma (Topical)
Side Effects
Myelosuppression
Mucositis
Severe Diarrhea
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3 mins
HIV CD4+ 500
Signs and Symptoms
Candida albicans (Oral Thrush)
Kaposi's Sarcoma (HHV-8)
Human Papillomavirus (HPV)
Epstein-Barr Virus (Oral Hairy Leukoplakia)
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3 mins
HIV CD4+ 200
Signs and Symptoms
Herpes Simplex Virus (HSV)
JC Virus
Progressive Multifocal Leukoencephalopathy (PML)
Pneumocystis Pneumonia
(HIV) Dementia
Histoplasmosis
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3 mins
HIV CD4+ 100
Signs and Symptoms
Aspergillus fumigatus
Cryptococcus neoformans
Candida albicans (Esophagitis)
Mycobacterium avium complex (MAC)
Cytomegalovirus (CMV)
Epstein-Barr virus (EBV) B-cell lymphoma
Toxoplasma gondii
Cryptosporidium
Bartonella henselae
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5 mins
Bruton (X-linked) Agammaglobulinemia (DEMO)
X-linked Recessive
Blocks B Cell Maturation
Decreased Immunoglobulins of all Classes
Recurrent Bacterial Infections after 6 Months
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1 min
Budd-Chiari Syndrome
Causes
Pregnancy and Postpartum
Hematologic Disorders
Tumors
Chronic Infections
Mechanism
Thrombosis of Major Hepatic Veins
Centrilobular Congestion and Necrosis
Symptoms
Abdominal Pain
Ascites
Hepatomegaly
Nutmeg Liver
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3 mins
Azathioprine (Imuran)
Mechanism
Antimetabolite
Prodrug of 6-mercaptopurine (6-MP)
Inhibits Synthesis of Nucleic Acids
Indications
Autoimmune Disorders
Kidney Transplantation
Side Effects
Myelosuppression
Increased Toxicity with Allopurinol Use
Pancreatitis
Malignancy
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3 mins
Huntington's Disease (DEMO)
Autosomal Dominant
Decreased GABA
Decreased Acetylcholine
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42 secs
Dilated Cardiomyopathy (DEMO)
Causes
Alcohol Use
Cocaine Use
Doxorubicin Toxicity
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1 min
Cushing Syndrome (DEMO)
More Common in Women
Endogenous Cause
Decreased ACTH
Exogenous Cause (Taken in from Outside)
Increased Glucocorticoids
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55 secs
Crohn's Disease Characteristics (DEMO)
Granulomas
Skip Lesions
Cobblestone Mucosa
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46 secs
Hodgkin's Lymphoma Characteristics (DEMO)
B Cell Origin
Owl's Eye Appearance
Bimodal Age Distribution
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1 min
Membranous Glomerulonephritis (DEMO)
Nephrotic
EM - Spike and Dome Appearance
IF Granular
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58 secs
Yolk Sac Tumor (DEMO)
Germ-cell Tumor
Aggressive Malignancy
Yellow, Friable, Solid
Schiller-Duval Bodies
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1 min
Trazodone (DEMO)
Indications
Insomnia
Mechanism of Action
Inhibits Serotonin Reuptake
Side Effects
Sedation
Priapism
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55 secs

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