OnlineMedEd Shared "Glomerular Filtration" - 8 Picmonics

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Glomerular Filtration

Renal Corpuscle
Characteristics
Arterioles
Glomerulus
Capillaries
Fenestrations
Plasma Solutes and Other Small Molecules Become Ultrafiltrate
Bowman's Capsule Encapsulates Glomerulus
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2 mins
Collecting Duct
Characteristics
Na+ Reabsorption via Passive Transport
Vasopressin Causes Water reabsorption
Concentrates Filtrate
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2 mins
Loop of Henle
Characteristics
Descending Limb
Water Follows Na+
Medullary Hypertonicity
Increased Water Reabsorption
Vasa Recta
Na+ Reabsorbed Via Active Transport
Ascending Limb
Reabsorbs Na+, K+, Cl-
Decreased Concentration of Filtrate
Impermeable to Water
Distal Tubule
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2 mins
Proximal Tubule
Characteristics
Na+ Reabsorbed Via Active Transport
Water Follows Na+
Most Of Glucose Reabsorbed
Most Of Amino Acids Reabsorbed
Bicarbonate Exchanged For H+
Drugs and Toxins Excreted
Filtrate Osmolarity Same As Plasma
Leads To Loop Of Henle
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2 mins
Urinary Excretory Anatomy
Characteristics
Renal Medulla
Renal Cortex
Nephron
Bowman's Capsule
Glomerulus
Proximal Tubule
Loop of Henle
Distal Tubule
Collecting Duct
Ureter
Urinary Bladder
Urethra
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2 mins
Renin Angiotensin Aldosterone System (RAAS) Regulators
Activators
Hypotension
Hypovolemia
Decreased NaCl Delivery to Macula Densa
Sympathetic Stimuli
Key Mediators
Angiotensin II
Aldosterone
Antidiuretic Hormone
Negative Feedback
Atrial Natriuretic Peptide and Brain Natriuretic Peptide
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2 mins
Angiotensin II Synthesis
Juxtaglomerular Apparatus
Juxtaglomerular Cells
Mesangial Cells
Macula Densa
Distal Tubule
KEY MEDIATORS
Angiotensinogen
Secreted from Liver
Renin
Secreted from Juxtaglomerular Cells
Catalyzes Angiotensinogen to Angiotensin I
Angiotensin Converting Enzyme (ACE)
Pulmonary Capillaries
Catalyzes Angiotensin I to Angiotensin II
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3 mins
Angiotensin II Effects
Effects On Vasculature
Increases Vascular Smooth Muscle Contraction
Increases Blood Pressure
Effects on Kidney
Efferent Arteriole Vasoconstriction
Increases GFR
Proximal Tubule
Sodium and Water Reabsorption
Adrenal Cortex
Increases Aldosterone Secretion
Effects on CNS
Stimulates Posterior Pituitary Gland to Secrete Vasopressin (ADH)
Stimulates Thirst in Hypothalamus
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2 mins

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