Tristan Shared "MSK Exam 1" - 44 Picmonics
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MSK Exam 1
Osteogenesis Imperfecta
- Pathophysiology
- Autosomal Dominant
- Decreased Type I Collagen Production
- Symptoms
- Phenotypically Diverse
- Brittle Bone Disease
- Fractures from Minimal Trauma
- Confused with Child Abuse
- Hearing Loss
- Dental Imperfections
- Blue Sclera
1 min
Achondroplasia
- Mechanism
- Autosomal Dominant
- Advanced Paternal Age
- Most Common Cause of Dwarfism
- Mutation of FGFR3 (Fibroblast Growth Factor Receptor 3)
- Defective Endochondral Ossification
- Symptoms
- Delayed Motor Milestones
- Shortened Limbs with Normal Axial Skeleton Size
- May Develop Hydrocephalus
- Symptoms of Spinal Stenosis
- Normal Life Span and Fertility
2 mins
Fibrous Dysplasia
- Pathophysiology
- Bone Replaced by Collagen and Fibroblasts
- Location
- Face and Skull
- Ribs
- Long Bones of Arms and Legs
- Sign and Symptom
- Bone Pain
- Diagnosis
- "Ground Glass" Appearance on Imaging
- Complication
- Fracture
- Association
- McCune-Albright Syndrome
- Treatment
- Supportive
2 mins
Osteopetrosis (Marble Bone Disease)
- Pathophysiology
- Defective Osteoclast Resorption
- Carbonic Anhydrase II Mutation
- Lack of Acidic Environment
- Symptoms
- Fractures
- Nerve Palsies
- Diagnosis
- Myelophthisic Anemia
- Erlenmeyer Flask Bones
- Normal ALP and PTH
- Normal Calcium and Phosphorus
- Bone-in-bone Appearance
- Treatment
- Bone Marrow Transplant
2 mins
Paget's Disease of Bone
- Pathophysiology
- Men > Age 40
- Increased Osteoblast and Osteoclast activity
- Mosaic Pattern
- Signs and Symptoms
- Increased Skull Diameter
- Hearing Loss
- Fractures
- Bone Ache and Joint Pain
- High Output Heart Failure
- Diagnosis
- Bone Scan
- Normal Parathyroid hormone (PTH) and Calcium
- Elevated ALP
- Treatment
- Bisphosphonate
- Calcitonin
2 mins
Legg-Calve-Perthes Disease
- Pathophysiology
- Idiopathic Avascular Necrosis of Femoral Head
- Boys 5-7 Years of Age
- Symptoms < 18 Months
- Signs & Symptoms
- Painless Limp
- Limited Range of Motion
- Intermittent Anterior Thigh Pain
- Insidious Pain in Knee
- Atrophy of Upper Thigh
- Diagnosis
- AP and Frog Leg Lateral X-ray
- Compression and Deformity of Femoral Head
- Treatment
- Bed Rest
- NSAIDs
- Containment with Brace or Cast
- Surgery
4 mins
Slipped Capital Femoral Epiphysis (SCFE)
- Pathophysiology
- Separation of Femoral Epiphysis from Femoral Neck
- Through Growth Plate (Physeal Plate)
- Obesity
- Male Adolescents
- African American
- Growth and Sex Hormone Imbalances
- Signs & Symptoms
- Thigh or Knee Pain
- Inability to Bear Weight
- Decreased Internal Rotation of Hip
- Obligate External Rotation of Hip with Flexion
- Diagnosis
- Frog Leg Lateral X-ray
- Treatment
- Surgical Pinning
- Complications
- Avascular Necrosis of Femoral Head
3 mins
Osteomyelitis
- Cause/Mechanism
- Bone Infection
- Assessment
- Warmth
- Edema
- Constant Bone Pain
- Fever
- Interventions
- IV Antibiotics
- Implanted Beads
- Hyperbaric Oxygen
- Surgical Removal of Ischemic Tissue
- Considerations
- Elevated ESR
3 mins
Osteoporosis Assessment
- Highest Risk
- Postmenopausal Women
- Long Term Corticosteroids
- Assessment
- Kyphosis
- Dowager's Hump
- Loss of Height
- Back Pain
- Pathologic Fractures
- Spinal Compression Fracture
1 min
Osteoporosis Interventions
- Increased Calcium Intake
- Vitamin D Supplements
- Bisphosphonates
- Raloxifene
- Denosumab
- Calcitonin
- Teriparatide
- Bone Densitometry (DEXA) Scan
- Weight Bearing Exercises
2 mins
Vitamin D Deficiency
- Signs & Symptoms
- Rickets in children
- Bending bones
- Rachitic rosary
- Breast milk has decreased vitamin D
- Osteomalacia in adults
- Tetany from Hypocalcemia
2 mins
Vitamin C Mechanism and Deficiency
- Mechanism
- Ascorbic acid
- Antioxidant
- Protects Against Free Radicals
- Keeps Iron in Reduced State
- Hydroxylation of Proline and Lysine
- Necessary for Dopamine B Hydroxylase
- Deficiency Signs and Symptoms
- Scurvy
- Swollen Gums
- Bruising
- Poor Wound Healing
- Hemarthrosis
- Perifollicular Hemorrhages
- Anemia
4 mins
Primary Hyperparathyroidism
- Assessment
- Hypercalcemia
- Kidney Stones
- Osteoporosis
- Arrhythmias
- Diagnostic Tests
- Increased Calcium and Decreased Phosphorus
- Considerations
- Prevent Injury
- Medication Education
- Surgery
1 min
Secondary Hyperparathyroidism
- Characteristics
- Hypocalcemia or Hyperphosphatemia
- Increased Parathyroid Hormone (PTH)
- Increased Alkaline Phosphatase (ALK-P)
- Reactive Parathyroid Hyperplasia
- Etiologies
- Chronic Kidney Disease
- Vitamin D Deficiency
- Diagnosis
- Laboratory Tests
- Management
- Treat Underlying Disorder
- Phosphate Binders
- Vitamin D Supplements
2 mins
Osteoma
- Benign
- Cortex
- Compact and Wavy (Trabecular) Bone
- Skull and Paranasal Sinuses
- Symptoms are Variable
- ASSOCIATIONS
- Gardner Syndrome
- Tuberous Sclerosis
- CHARACTERISTICS
- Lesions with Density Identical to the Cortex
- TREATMENT AND PROGNOSIS
- Observation
- No Malignant Transformation
3 mins
Osteoid Osteoma and Osteoblastoma
- Characteristics
- Benign Bone Tumors
- Osteoid Osteoma
- Osteoid Osteoma
- Cortex of Long Bones
- Pain Relieved by NSAIDs
- Pain Worse at Night
- <2 cm
- Radiolucent Nidus with Surrounding Sclerosis
- Osteoblastoma
- Osteoblastoma
- Spine
- Pain Not Relieved by NSAIDs
- > 2 cm
- Radiolucent Nidus without Surrounding Sclerosis
- Management
- Surgery
3 mins
Osteosarcoma
- Pathophysiology
- Osteogenic Sarcoma
- Peak incidence men 10-20 years old
- Metaphysis of Long Bones
- Knee Region
- Radiation
- Familial Retinoblastoma
- Paget's Disease
- Diagnosis
- Codman Triangle
- Sunburst Pattern from Elevated Periosteum
- Grave Prognosis
2 mins
Osteochondroma
- Characteristics
- Most Common Benign Bone Tumor
- Males Under 25
- Cartilage-capped Spurs
- Metaphysis of Long Bones
- Small Risk of Chondrosarcoma
- Clinical Features
- Painless Mass near Joint
- Painful if Growing or Malignant
- Workup
- X-Ray
- MRI if Concern for Malignancy or Functional Limitation
- Management
- Monitoring
- Surgery
3 mins
Chondrosarcoma
- Pathophysiology
- Cartilaginous tumor
- Malignant
- Men 30-60 years old
- Pelvic and femur bones
- Signs & Symptoms
- Glistening mass in medullary cavity
- Can be primary in origin or from osteochondroma
- Metastasize to lungs
1 min
Giant Cell Tumor
- Pathophysiology
- Osteoclastoma
- Epiphyseal End of Long Bones
- Peak Incidence 20-40 Years
- Benign
- Knee Region
- Diagnosis
- Soap Bubble Appearance on X-ray
- Spindle-shaped Cells
- Multinucleated Giant Cells
46 secs
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