Chiamaka Shared "CM ENDO 1" - 13 Picmonics

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CM ENDO 1

Kallman Syndrome
Mutation in KAL-1 or FGFR-1 Gene
Failure of GnRH Secreting Neurons
Delayed Puberty
Anosmia
Hypogonadism
Infertility
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2 mins
MEN 1 (Multiple Endocrine Neoplasia)
Pathophysiology
Autosomal Dominant
Menin Mutation (Tumor Suppression Gene)
Chromosome 11
Signs and Symptoms
Pancreatic Endocrine Tumors
Pituitary Tumors
Parathyroid Adenomas
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2 mins
MEN 2A (Multiple Endocrine Neoplasia)
Pathophysiology
Autosomal Dominant
RET Gene
Signs and Symptoms
Medullary Thyroid carcinoma
Calcitonin
Parathyroid
Pheochromocytoma
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44 secs
MEN 2B (Multiple Endocrine Neoplasia)
Pathophysiology
RET Gene
Autosomal Dominant
Signs and Symptoms
Medullary Thyroid Carcinoma
Pheochromocytoma
Marfanoid Body Habitus
Oral Ganglioneuromatosis
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55 secs
Cushing's Syndrome Characteristics
More Common in Women
Exogenous Etiologies
Glucocorticoids
Endogenous Etiologies
Decreased ACTH
Primary Adrenal Disease
Increased ACTH
Pituitary Adenoma (Cushing's Disease)
Paraneoplastic: Small Cell Carcinoma
CRF-releasing Tumors
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2 mins
Cushing's Syndrome Symptoms And Diagnosis
Symptoms/Findings
Osteoporosis
Amenorrhea
Truncal Obesity
Skin Changes
Buffalo Hump
Immune Suppression
Moon Facies
Hypertension
Decreased Insulin Sensitivity
Diagnosis
24-hour urine free Cortisol
Dexamethasone Suppression Test
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2 mins
Acromegaly Assessment
Mechanism
Mechanism
Excess Growth Hormone (GH)
Excess Growth Hormone (GH)
Signs and Symptoms
Signs and Symptoms
Protruding Jaw
Protruding Jaw
Large Lips and Nose
Large Lips and Nose
Hearing Loss
Hearing Loss
Enlargement of Hands and Feet
Enlargement of Hands and Feet
Vision Changes and Headache
Vision Changes and Headache
Joint Pain
Joint Pain
Peripheral Neuropathy
Peripheral Neuropathy
Hyperglycemia
Hyperglycemia
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2 mins
11 Beta-Hydroxylase Deficiency
Pathophysiology
Pathophysiology
Pathophysiology
Pathophysiology
Pathophysiology
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Increased Sex Hormones
Increased Sex Hormones
Increased Sex Hormones
Increased Sex Hormones
Increased Sex Hormones
Increased 11 Deoxycorticosterone (11 DOC)
Increased 11 Deoxycorticosterone (11 DOC)
Increased 11 Deoxycorticosterone (11 DOC)
Increased 11 Deoxycorticosterone (11 DOC)
Increased 11 Deoxycorticosterone (11 DOC)
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Hypertension
Hypertension
Hypertension
Hypertension
Hypertension
Masculinization
Masculinization
Masculinization
Masculinization
Masculinization
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1 min
21 Hydroxylase Deficiency
Pathophysiology
Pathophysiology
Pathophysiology
Pathophysiology
Pathophysiology
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Increased 17 Hydroxyprogesterone
Increased 17 Hydroxyprogesterone
Increased 17 Hydroxyprogesterone
Increased 17 Hydroxyprogesterone
Increased 17 Hydroxyprogesterone
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Decreased Aldosterone
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Signs and Symptoms
Hypotension
Hypotension
Hypotension
Hypotension
Hypotension
Increased Renin
Increased Renin
Increased Renin
Increased Renin
Increased Renin
Hyperkalemia
Hyperkalemia
Hyperkalemia
Hyperkalemia
Hyperkalemia
Female Pseudohermaphroditism
Female Pseudohermaphroditism
Female Pseudohermaphroditism
Female Pseudohermaphroditism
Female Pseudohermaphroditism
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2 mins
17 Alpha Hydroxylase Deficiency
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Cortisol
Decreased Sex Hormones
Decreased Sex Hormones
Decreased Sex Hormones
Decreased Sex Hormones
Decreased Sex Hormones
Increased Mineralocorticoids (DOC)
Increased Mineralocorticoids (DOC)
Increased Mineralocorticoids (DOC)
Increased Mineralocorticoids (DOC)
Increased Mineralocorticoids (DOC)
Hypertension
Hypertension
Hypertension
Hypertension
Hypertension
Hypokalemia
Hypokalemia
Hypokalemia
Hypokalemia
Hypokalemia
XY Externally Phenotypic Female
XY Externally Phenotypic Female
XY Externally Phenotypic Female
XY Externally Phenotypic Female
XY Externally Phenotypic Female
No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
XX Externally Phenotypic Female
XX Externally Phenotypic Female
XX Externally Phenotypic Female
XX Externally Phenotypic Female
XX Externally Phenotypic Female
Sexual Infantilism
Sexual Infantilism
Sexual Infantilism
Sexual Infantilism
Sexual Infantilism
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2 mins
Pheochromocytoma
Cause/Mechanism
Adrenal Medulla Tumor
Increased Catecholamines
Assessment
Episodic Hypertension
Diaphoresis
Abdominal or Chest Pain
Interventions
Surgery
Antihypertensives
Phenoxybenzamine
Metyrosine (Demser)
Considerations
Do Not Palpate Abdomen
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3 mins
Polycystic Ovarian Syndrome (PCOS) Symptoms and Diagnosis
Symptoms
Most Common Cause of Infertility in Women
Amenorrhea
Acne
Hirsutism
Obesity
Diagnosis
Enlarged, Cystic Ovaries
LH:FSH Ratio of 3:1
"String of Pearls" on Ultrasound
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1 min
Turner Syndrome
Signs and Symptoms
Female (XO)
Short stature
Shield Chest
Cystic Hygroma (Webbing of Neck)
Lymphedema in Hands and Feet
Ovarian Dysgenesis
Streak Ovary
Decreased Estrogen
Increased FSH
Increased LH
Dysgerminoma
Bicuspid Aortic Valve
Preductal Coarctation of the Aorta
Horseshoe Kidney
Menopause before Menarche
Amenorrhea
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5 mins

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