Faith Shared "Pharm Chapt 1-3" - 25 Picmonics
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Pharm Chapt 1-3
Vancomycin
- Mechanism of Action
- Inhibits Bacterial Cell Wall Synthesis
- Indications
- Serious Gram-Positive Infections
- Side Effects
- Nephrotoxicity
- Ototoxicity
- Red Man Syndrome
- Thrombophlebitis
- Nursing Considerations
- Culture Samples First
- Infuse IV Over 60 Minutes
- Take Around the Clock
2 mins
Fluoroquinolones
- End in "-floxacin"
- Mechanism of Action
- Bactericidal
- Indications
- Variety of Infections
- Side Effects
- GI Distress
- Photosensitivity
- Achilles Tendon Rupture
- Contraindications
- Pregnancy
- Children
- Myasthenia Gravis
- Considerations
- Avoid Milk Products or Antacids
- Slow IV Infusion
2 mins
Aminoglycoside Overview
- End in "-mycin"
- GNATS
- Gentamicin
- Neomycin
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Requires Oxygen for Uptake
- Synergistic with β-lactam Antibiotics
- Indications
- Severe Gram-Negative Infections
- Bowel Surgery Prep
- MECHANISM OF RESISTANCE
- Bacterial Transferases
3 mins
Aminoglycoside Side Effects
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Contraindications
- Pregnancy
- Considerations
- Peak and Trough
- Never Mix with Penicillin in Same IV
2 mins
Second Generation Antihistamines
- Indications
- Allergies
- Mechanism of Action
- Lipophobic
- Histamine H1 Receptor Antagonist
- Drugs
- Azelastine + Fluticasone (Dymista)
- Intranasal Spray
- Cetirizine (Zyrtec)
- Loratadine (Claritin)
- Fexofenadine (Allegra)
- Considerations
- Fewer Anticholinergic Effects
- Fewer CNS Effects
2 mins
Vancomycin Side Effects & Toxicity
- Side Effects
- Thrombophlebitis
- Nephrotoxicity
- Ototoxicity
- Diffuse Flushing Called Red Man Syndrome
- Prevent with Antihistamine
- Prevent with Slow Infusion
2 mins
Tuberculosis Skin Mantoux Test (PPD)
- Delayed Hypersensitivity (Cell Mediated Response)
- Intradermal Injection
- Read 48-72 hours
- Positive Results
- ≥ 5 mm Induration
- Immunosuppressed
- ≥ 10 mm Induration
- High Risk Patients
- ≥ 15 mm Induration
- Considerations
- Chest X-Ray
3 mins
Hookworm Infection
- Characteristics
- Necator Americanus
- Ancylostoma spp
- Nematode (Roundworm)
- Mode of transmission
- Larvae in Soil Penetrate Skin
- Pathophysiology
- Larvae Migrate To Lungs
- Larvae Mature In The Intestine
- Risk Factors
- Walking Barefoot On Contaminated Ground
- Signs & Symptoms
- Cutaneous Symptoms
- Microcytic Anemia
- Treatment
- Albendazole
- Pyrantel Pamoate
4 mins
Azoles (Ketoconazole)
- "-azole" suffix
- Indications
- Local and Less Serious Systemic Mycosis
- Mechanism
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Side Effects
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
1 min
Integrase Inhibitors
- -gravir Suffix
- Indications
- HIV
- Mechanism
- Blocks Insertion of Viral Genome
- Inhibit Actions of Integrase
- Side Effects
- Hypercholesterolemia
- Increased LFT's
- Insomnia
- Increased Creatine Kinase (CK)
1 min
Pinworm (Enterobius Vermicularis)
- Pathophysiology
- Nematode (Roundworm)
- Ingestion of Eggs
- Intestinal Infection
- Anal Pruritus
- Diagnosis
- Scotch Tape Test
- Treatment
- Albendazole
- Pyrantel Pamoate
2 mins
Giardia lamblia
- Characteristics
- Protozoa
- Ingestion of Cysts
- Seen in Campers
- Daycare Centers
- Mental Hospitals
- Infects Small Intestine
- Signs and Symptoms
- Bloating
- Flatulence
- Fatty Diarrhea
- Diagnosis
- Crescent-shaped Protozoa Adjacent to Epithelial Brush Border
- Predisposed if Low IgA
- Treatment
- Metronidazole
3 mins
Herpes Simplex Virus (HSV)
- Characteristics
- Enveloped
- Double Stranded DNA
- Linear
- Signs and Symptoms
- Type 1 HSV
- Gingivostomatitis
- Keratoconjunctivitis
- Encephalitis of Temporal Lobes
- Latent in Trigeminal Ganglia
- Type 2 HSV
- Genital Vesicles
- Neonatal Herpes
- TORCHES
- Latent in Sacral Ganglia
- Diagnosis
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusions
- Treatment
- Acyclovir
2 mins
Paracoccidioido-mycosis
- Fungi
- Latin America
- Common in Brazil
- Budding yeast with captain wheel formation
- 40-50 um
- Pneumonia
39 secs
Cryptococcus neoformans
- Characteristics
- Monomorphic
- Encapsulated
- Polysaccharide Capsule
- Narrow-Based Buds
- Latex Agglutination
- Pigeons
- India Ink
- Mucicarmine stain
- Signs and Symptoms
- AIDS/Immunocompromised
- Meningitis
- Soap Bubble Lesions in Brain
- Pneumonia
- Treatment
- Fluconazole
- Flucytosine
- Amphotericin
3 mins
Isoniazid
- Indications
- Tuberculosis (TB)
- Mechanism of Action
- Requires Catalase Peroxidase
- Decreases Mycolic Acid Synthesis
- Fast vs Slow Acetylators
- Side Effects
- B6 Deficiency
- Neurotoxicity
- Hepatotoxicity
- Drug-induced Lupus
1 min
Mycobacterium Tuberculosis Characteristics
- Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation TB
- Reactivation in Apex
3 mins
HIV CD4+ 100
- Signs and Symptoms
- Aspergillus fumigatus
- Cryptococcus neoformans
- Candida albicans (Esophagitis)
- Mycobacterium avium complex (MAC)
- Cytomegalovirus (CMV)
- Epstein-Barr virus (EBV) B-cell lymphoma
- Toxoplasma gondii
- Cryptosporidium
- Bartonella henselae
5 mins
Trichinella Spiralis (Trichinellosis)
- Characteristics
- Nematode
- Pathogenesis
- Undercooked Meat (Especially Pork)
- Larvae Enter Bloodstream and Encyst in Striated Muscle
- Signs and Symptoms
- Nausea and Vomiting
- Myalgia
- Fever
- Periorbital Edema
- Eosinophilia
- Treatments
- Albendazole
2 mins
Mycobacterium Tuberculosis Disease
- CONSTITUTIONAL SYMPTOMS/PULMONARY TUBERCULOSIS
- Fever
- Night Sweats
- Weight Loss
- Hemoptysis
- EXTRA-PULMONARY TUBERCULOSIS
- Extrapulmonary Disease
- Addison's Disease
- CNS
- Liver
- Kidneys
- GI
- Bones
- Pott's Disease
3 mins
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