Alyssa Shared "N4 Exam 4" - 46 Picmonics
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N4 Exam 4
Ticlopidine (Ticlid)
- Mechanism
- ADP Receptor Antagonist
- Irreversibly Inhibits Platelet Aggregation
- Indications
- Thrombotic Event Prevention
- Side Effects
- Neutropenia
- Thrombotic Thrombocytopenic Purpura (TTP)
- GI Distress
- Rash
- Considerations
- Withhold Before Surgery
- Monitor Blood Count
2 mins
Busulfan
- Indications
- CML
- Bone Marrow Ablation
- Mechanism
- Cross-Links DNA
- Side Effects
- Myelosuppression
- Pulmonary Fibrosis
- Hyperpigmentation
55 secs
Cisplatin (Platinol)
- Mechanism
- Alkylating Agent
- Cross-Links DNA
- Indications
- Testicular Cancer
- Ovarian Cancer
- Side Effects
- Nausea and Vomiting
- Myelosuppression
- Nephrotoxicity
- Ototoxicity
- Peripheral Neuropathy
- Considerations
- Antiemetics Before Administration
- Aggressive Hydration
3 mins
Vincristine (Oncovin)
- Mechanism
- Vinca Alkaloid
- Inhibits Microtubules
- Indications
- Leukemias
- Lymphomas
- Side Effects
- Peripheral Neuropathy
- Paralytic Ileus
- Considerations
- Vesicant
2 mins
Bleomycin
- Indications
- Testicular Cancer
- Hodgkin's Lymphoma
- Mechanism of Action
- Induces Free Radical Formation
- Breaks in DNA Strands
- Side Effects
- Pulmonary Fibrosis
- Skin Changes
- Mucositis
1 min
Hydroxyurea
- Mechanism
- Inhibits Ribonucleotide Reductase
- Decreased DNA Synthesis
- S-phase Specific
- Indications
- Melanoma
- Chronic Myelogenous Leukemia (CML)
- Sickle Cell Disease
- Through Increased HbF (Fetal Hemoglobin)
- Side Effects
- Myelosuppression
- GI Distress
2 mins
Cyclophosphamide
- Mechanism
- Requires Bioactivation by Liver
- Cross-links DNA
- Guanine N7 Position
- Indications
- Autoimmune Disorders
- Leukemia
- Lymphoma
- Solid Tumors
- Side Effects
- Myelosuppression
- Hemorrhagic Cystitis
- Prevent with Mesna
3 mins
Rituximab
- Indications
- Chronic Lymphocytic Leukemia (CLL)
- Non-Hodgkin Lymphoma
- Rheumatoid Arthritis
- Microscopic Polyangiitis (MPA)
- Granulomatosis with Polyangiitis (Formerly Wegener's)
- Mechanism
- Monoclonal Antibody Against CD20
- Found on B Cell Neoplasms
- Side Effects
- Infusion Reactions
- Skin and Mouth Reactions
- Reactivation of Hepatitis B Virus (HBV)
- Progressive Multifocal Leukoencephalopathy (PML)
3 mins
Cancer Warning Signs (CAUTION)
- CAUTION
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
1 min
ABCDEs of Melanoma
- Asymmetry
- Border
- Color
- Diameter
- Evolving
1 min
Breast Cancer Diagnosis
- Mammography
- Ultrasound
- MRI for High Risk Patients
- Confirmed with Biopsy
- Considerations
- Lymph Node Involvement
- Receptor Positivity
- Estrogen and Progesterone Receptors
- HER-2
2 mins
Breast Cancer Interventions
- Radiation or Chemotherapy
- Hormonal Therapy
- Tamoxifen
- Lumpectomy
- Mastectomy
- Avoid BP and Injections Affected Arm
- Hand Exercises
- Considerations
- Grief Related to Body Image
- Prosthetics
- Reconstruction
- Lymphedema
3 mins
Prostate Cancer Assessment
- Most Common Cancer in Men
- Assessment
- Mimics BPH
- Metastasis to Back
- Low Back Pain
- Fatigue
- Considerations
- Prostate Specific Antigen (PSA)
- Digital Rectal Examination (DRE)
- Transrectal Ultrasound (TRUS)
- Biopsy
2 mins
Cervical Cancer Assessment
- Cause/Mechanism
- Human Papillomavirus (HPV)
- Assessment
- Metrorrhagia
- Leukorrhea
- Pain
- Abnormal Pap Test
- May Be Asymptomatic
- Considerations
- HPV Vaccine
2 mins
Cervical Cancer Screening
- Women Aged 21-65 Years
- Pap Smear Every 3 Years
- Women Aged 30-65 Years
- Can Opt for Co-testing (Pap Smear + HPV Testing) Every 5 Years
- Identify Lesions
- High grade lesions
- Cryotherapy
- Loop Excision
- Cold Knife Conization
2 mins
Testicular Carcinoma Assessment
- Cause/Mechanism
- Seminoma Germ Cells
- Non-Seminoma Germ Cells
- Assessment
- Painless Scrotal Mass
- Testicular Swelling
- Acute Pain Rare
- Elevated Serum Tumor Markers
- Considerations
- Males Between 15-35 Years Old
- Cryptorchidism
- Testicular Self Exam
2 mins
Colorectal Cancer Assessment
- 3rd Most Common Cancer
- Assessment
- Change in Bowel Habits
- Bowel Obstruction
- Rectal Bleeding
- Anemia
- Weight Loss
- Ascites
- Considerations
- Colonoscopy
- FOBT and FIT
2 mins
Colorectal Cancer Interventions
- Interventions
- Surgical Colon Resection
- Radiation
- Chemotherapy
- Considerations
- Bowel Cleansing
- Screening
- Colostomy
- Dietary Consult
- Body Image
3 mins
Lung Cancer Assessment
- 2nd Most Common Cancer
- Assessment
- Chronic Cough
- Hoarseness
- Abnormal Breath Sounds
- Hemoptysis
- Chest Pain
- Anorexia or Weight Loss
- Considerations
- Symptoms Appear Late in Disease
2 mins
Wilms' Tumor (Nephroblastoma)
- Cause
- Malignant Renal Tumor
- Assessment
- Abdominal Mass
- Hematuria
- Fever
- Hypertension
- Interventions
- Nephrectomy
- Chemotherapy
- Radiation
- Considerations
- Do Not Palpate Abdomen
- Children Under 5 Years Old
2 mins
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