Whitney Shared "Patho Exam 3" - 62 Picmonics
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Patho Exam 3
Hypertension Medications
- Diuretics
- ACE Inhibitors
- Angiotensin Receptor Blockers (ARBs)
- Beta Blockers
- Dihydropyridine Calcium Channel Blockers
2 mins
Osteoporosis Interventions
- Increased Calcium Intake
- Vitamin D Supplements
- Bisphosphonates
- Raloxifene
- Denosumab
- Calcitonin
- Teriparatide
- Bone Densitometry (DEXA) Scan
- Weight Bearing Exercises
2 mins
Alendronate (Fosamax)
- Mechanism
- Inhibits Osteoclasts
- Indications
- Osteoporosis
- Paget's Disease
- Side Effects
- Esophageal Ulcers
- Musculoskeletal Pain
- Vision Changes
- Atrial Fibrillation
- Osteonecrosis of the Jaw
- Considerations
- Take on Empty Stomach
- Remain Upright
2 mins
Raloxifene
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Agonist in Bone
- Antagonist in Breast and Uterus
- Indications
- Osteoporosis
- Breast Cancer Prophylaxis
- Uterine Fibroids
- Side Effects
- Hot Flashes
- Thromboembolism
2 mins
Methotrexate
- Indications
- Rheumatoid Arthritis
- Cancer
- Medical Abortion
- Mechanism
- Folic Acid Analog
- Inhibits Dihydrofolate Reductase
- Side Effects
- Pulmonary Fibrosis
- Myelosuppression is Treated with Leucovorin Rescue (Folinic Acid)
- Macrocytic Anemia
- Hepatitis
- Teratogenic
- Mucositis
2 mins
Hydrochlorothiazide HCTZ
- Mechanism of Action
- Inhibits Reabsorption NaCl and H2O
- Indications
- Edema
- Mild to Moderate Hypertension
- Side Effects
- Hypokalemia
- Hyponatremia
- Dehydration
- Hyperglycemia
- Gout
- Contraindications
- Sulfa Allergy
- Pregnancy and Breastfeeding
1 min
Hematocrit (Hct) Lab Values
- Women: 36% - 46%
- Men: 41% - 53%
1 min
Rheumatoid Arthritis Interventions
- Lifestyle Modifications
- Heat and Cold Applications
- Therapeutic Exercise
- Balance Rest and Activity
- Drug Therapy
- NSAIDs
- DMARDs
- Glucocorticoids
- Considerations
- PT/OT
- Reconstructive Joint Surgery
2 mins
Rheumatoid Arthritis Assessment
- Mechanism
- Destruction of Connective Tissue and Synovial Membrane
- Signs and Symptoms
- Inflammation of Joints
- Morning Stiffness
- Nodules
- Joint Deformities
1 min
Osteoarthritis
- Mechanism
- Articular Cartilage Destruction
- Biomechanical Stress
- Aging
- Signs and Symptoms
- Asymmetric
- Pain Decreases with Rest
- Morning Stiffness Under 30 Minutes
- Crepitus
- DIP and PIP Joints
- Treatment
- Lifestyle Changes
- Acetaminophen or NSAIDs
2 mins
Osteoarthritis Assessment
- Mechanism
- Aging
- Articular Cartilage Destruction
- Biomechanical Stress
- Signs and Symptoms
- Asymmetric
- Pain Decreases with Rest
- Morning Stiffness under 30 Minutes
- Crepitus
- DIP and PIP Joints
1 min
Osteoarthritis Interventions
- Lifestyle Modifications
- Balance Rest and Activity
- Therapeutic Exercise
- Heat and Cold Applications
- Drug Therapy
- Intra-articular Injection
- NSAIDs
- Considerations
- Reconstructive Joint Surgery
1 min
Osteoporosis Assessment
- Highest Risk
- Postmenopausal Women
- Long Term Corticosteroids
- Assessment
- Kyphosis
- Dowager's Hump
- Loss of Height
- Back Pain
- Pathologic Fractures
- Spinal Compression Fracture
1 min
Gout Disease
- Acute Inflammatory Monoarthritis
- Epidemiology
- Primarily in Males
- Pathophysiology
- Precipitation of Monosodium Urate Crystals
- Underexcretion of Uric Acid
- Overproduction of Uric Acid
- Negatively Birefringent, Needle-Shaped
- Symptoms
- Swollen, Red, Painful Joint
- Asymmetric Joint Distribution
- Podagra
- Tophus
- After Large Meal or Alcohol
2 mins
Gout Treatment
- Acute (Acute-angle)
- NSAIDs
- Glucocorticoids
- Colchicine
- Impairs Leukocyte Chemotaxis
- Chronic Gout (Crone Goat)
- Inhibit Xanthine Oxidase
- Allopurinol
- Febuxostat
- Inhibit Reabsorption of Uric Acid
- Probenecid
1 min
Platelet Lab Value
- 150,000-400,000 Micro L
40 secs
Enoxaparin (Lovenox)
- Mechanism of Action
- Inhibits Clotting Factors
- Factor Xa
- Indications
- Clot Formation Prevention
- Side Effects
- Heparin Induced Thrombocytopenia (HIT)
- Bleeding
- Considerations
- Medication Education
- Subcutaneous Injection
- 2 Inches from Umbilicus or Incisions
- Antidote
- Protamine Sulfate
2 mins
Heparin (Unfractionated)
- Mechanism of Action
- Suppresses Coagulation
- Indications
- Deep Vein Thrombosis (DVT)
- Pulmonary Embolism
- Side Effects
- Hemorrhage
- Heparin-Induced Thrombocytopenia (HIT)
- Considerations
- Monitor aPTT
- Preferred (Safe) During Pregnancy
- Antidote
- Protamine Sulfate
2 mins
Heparin Induced Thrombocytopenia (HIT)
- Pathophysiology
- 5-10 Days After Heparin Exposure
- Heparin-Platelet Factor 4 Complex
- Autoantibodies Form Against Complex
- Heparin-Platelet Factor 4-Antibody Complex Binds Platelets
- Platelet Aggregation
- Procoagulant Release
- Symptoms
- Thrombocytopenia
- Diagnosis
- Serotonin Release Assay (SRA)
- Treatment
- Stop Heparin, Start Direct Thrombin Inhibitor
2 mins
Venous Thromboembolism (DVT) Assessment
- Mechanism
- Venous Wall Inflammation caused by Thrombus
- Assessment
- Tenderness
- Edema
- Warmth
- Asymmetry
- Considerations
- Could be Asymptomatic
- Monitor for Pulmonary Embolism
58 secs
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