Heather Shared "neuro path" - 108 Picmonics
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neuro path
Multiple Sclerosis Features and Mechanisms
- Features
- More Common in Women
- Presents in 20's and 30's
- Northern Europeans
- Mechanism
- Unknown mechanism, genetic factor
- HLA-DRB1
- Autoimmune Demyelination of CNS
- White Matter of Brain and Spinal Cord
- T Cell Mediated Inflammation
2 mins
Multiple Sclerosis Symptoms and Diagnosis
- Symptoms
- Optic Neuritis
- Internuclear Ophthalmoplegia
- Scanning Speech
- Urinary and Fecal Incontinence
- Motor Issues (Intention Tremor, Paresis)
- Numbness and Pain
- Depression
- Relapsing Symptoms
- Diagnosis
- Gold Standard = Plaques on MRI
- Increased CSF Immunoglobulins (IgG)
- Oligoclonal Bands
4 mins
Multiple Sclerosis Interventions
- Drug Therapy
- Corticosteroids
- Interferon Beta
- Dimethyl Fumarate (Tecfidera)
- Fingolimod (Gilenya)
- Mitoxantrone (Novantrone)
- Natalizumab (Tysabri)
- Considerations
- Increase Exercise
- Identify Triggers
2 mins
Guillain-Barre Syndrome Assessment
- Assessment
- Ascending Paralysis
- Muscle Weakness
- Paresthesias (Pins and Needles)
- Diplopia
- Difficulty Speaking
- Dysphagia
- Labile Blood Pressure
- Loss of Bowel and Bladder Control
- Considerations
- Aggressive Airway Management
2 mins
Lambert-Eaton Syndrome
- Mechanism
- Autoantibody to the Presynaptic Calcium Channel on Motor Neurons
- Inhibits Acetylcholine (ACh) Release at Neuromuscular Junction
- Paraneoplastic Syndrome
- Small Cell Lung Cancer
- Symptoms
- Proximal Muscle Weakness
- Improves with Muscle Use
- Autonomic Symptoms
- Extraocular Muscle Sparing
2 mins
Autonomic Dysreflexia
- Injury Above T6
- Assessment
- Paroxysmal Hypertension
- Bradycardia
- Diaphoresis
- Flushing Above Lesion
- Piloerection
- Nasal Congestion
- Headache
- Interventions
- Elevate Head of Bed
- Remove Noxious Stimuli
2 mins
Causes of Dementia
- Reversible Causes
- Intoxication or Medications
- Depression
- Normal Pressure Hydrocephalus
- Vitamin B12 Deficiency
- Metabolic Conditions
- Irreversible Causes
- Lewy Body Dementia
- Prion Disease
- Pick's Disease
- AIDS Dementia
- Alzheimer's Disease
- Multi-infarct (Vascular) Dementia
2 mins
5 A's of Alzheimer's Disease
- Agnosia
- Anomia
- Aphasia
- Apraxia
- Amnesia
1 min
Parkinson's Disease Assessment
- Assessment
- Decreased Dopamine
- Older Adult
- Cogwheel Rigidity
- Bradykinesia
- Shuffling Gait
- Resting Tremor
- Pill-Rolling
- Mask-Like Face
- Cognitive Decline
2 mins
Parkinson's Drugs
- Parkinsons Characteristics
- Decreased Dopamine
- Increased Acetylcholine
- Drug Names
- BALSA Acronym
- Bromocriptine
- Amantadine
- Levodopa
- Selegiline
- Antimuscarinics
2 mins
Parkinson's Disease Interventions
- Medications
- Levodopa/Carbidopa (Sinemet)
- Entacapone (Comtan)
- Selegiline (Eldepryl)
- Amantadine (Symmetrel)
- Bromocriptine (Parlodel)
- Benztropine (Cogentin)
- Considerations
- Allow Extra Time
- Ensure Patient Safety
- Surgery As Last Resort
2 mins
Amyotrophic Lateral Sclerosis (ALS)
- Assessment
- Progressive Muscle Weakness
- Systemic Muscle Wasting
- Fasciculations
- Spasticity
- Fatigue
- Considerations
- Riluzole (Rilutek)
- Stretching
- Little to No Cognitive Decline
- Respiratory Support
- Palliative Care
2 mins
Huntington's Disease
- Pathophysiology
- Autosomal Dominant
- Trinucleotide Repeat
- CAG Repeats
- Chromosome 4
- Anticipation
- Caudate
- Decrease of ACh
- Decrease of GABA
- Signs and Symptoms
- Chorea
- Dementia
- Depression
- Glutamate Toxicity
- Neuronal Death via NMDA Binding
3 mins
Normal Pressure Hydrocephalus
- Mechanism
- Elderly
- Idiopathic
- Decreased Absorption of CSF
- Ventricular Enlargement
- Symptom Triad
- Urinary Incontinence
- Ataxia (Gait)
- Cognitive Dysfunction
2 mins
Cauda Equina Syndrome
- Acute Loss of Lumbar Plexus Function
- Surgical Emergency
- Saddle Anesthesia
- Causes
- Inflammatory Disorders
- Spinal Stenosis
- Trauma
- Lesions
- Symptoms
- Urinary and Fecal Incontinence
- Sciatica
- Diagnosis
- Magnetic Resonance Imaging (MRI)
- Clinical
1 min
Kluver-Bucy Syndrome
- Bilateral Amygdala Lesion
- Associated with HSV-1
- Hyperorality
- Hypersexuality
- Disinhibited Behavior
1 min
Lewy Body Dementia
- Pathophysiology
- Unknown Etiology
- Decreased Acetylcholine
- Alpha-synuclein Defect
- Eosinophilic Cytoplasmic Inclusion
- Signs and Symptoms
- Visual Hallucinations
- Progressive Dementia
- Fluctuating Cognition
- REM Sleep Behavior Disorder
- Parkinsonism
- Treatment
- Acetylcholinesterase Inhibitors
3 mins
Craniopharyngioma
- Hypopituitarism
- Remnants of Rathke's Pouch
- Tooth-enamel Like Calcification
- Cholesterol Crystals
- Yellow Viscous Fluid
- Headache
- Bitemporal Hemianopsia
1 min
Pilocytic Astrocytoma
- Occurs Most Commonly in Kids
- Posterior Fossa
- Cerebellum
- Well Circumscribed
- GFAP
- Rosenthal Fibers
- Eosinophilic Corkscrew Fibers
1 min
Ependymoma
- Occur in Children
- Fourth Ventricle
- Hydrocephalus
- Perivascular Pseudorosettes
- Rod Shaped Blepharoplasts
- Cauda Equina in Adults
- Poor Prognosis
- Neurofibromatosis Type II
2 mins
