OnlineMedEd Shared "General Pharmacology - Pharmacodynamics" - 5 Picmonics

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General Pharmacology - Pharmacodynamics

Competitive Inhibition
Reversible Inhibition
Constant Vmax
Substrate Competes With Inhibitor For The Active Site
Inhibition Increases Km
1 min
Non-Competitive Inhibition
Characteristics
Reversible Inhibition
Substrate Freely Binds The Active Site
Inhibitor Strongly Binds Allosteric Site
Km Constant
Enzyme Has Different Conformational Form
Low Vmax
2 mins
High Potency Antipsychotic Drugs
High Potency Drugs
Fluphenazine
Trifluoperazine
Haloperidol
Side Effects
Extrapyramidal Symptoms
Short Term
Dystonia
Torticollis
Long Term
Tardive Dyskinesia
Parkinson's-like Symptoms
1 min
Low Potency Antipsychotic Drugs
Drugs
Chlorpromazine
Corneal Deposits
Thioridazine
Retinal Deposits
Shared Side Effects
Alpha1 Antagonist Effects
Anticholinergic Effects
51 secs
Acute Digoxin Toxicity
Clinical Symptoms
Hyperkalemia
Cholinergic (Nausea, Vomiting, Diarrhea)
Blurry Yellow Green Vision with Halo of Light
Arrhythmia
Bradycardia
EKG Changes
Prolonged PR interval
Decreased QT
Scooping on EKG
T Wave Inversion
2 mins

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