Wayne Shared "Pharmacology 5/27/2024" - 23 Picmonics
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Pharmacology 5/27/2024
Primary Angle-Closure Glaucoma (PACG - Acute)
- Mechanism
- Rapid Increase in IOP
- Signs and Symptoms
- Rapid Onset
- Pain
- Blurred Vision
- Halos Around Lights
- Nausea and Vomiting
- IOP over 30 mm Hg
- Considerations
- Drug Therapy
- Surgery
1 min
Open-Angle Glaucoma
- Humor Has Access to Trabecular Meshwork
- Presentation
- Painless
- African American
- Elderly
- Positive Family History
- Primary Open-Angle Glaucoma
- Most Common Form of Glaucoma
- Unknown Mechanism
- Secondary Open-Angle Glaucoma
- Blocked Trabecular Meshwork (With Open-Angle)
- WBCs
- Red Blood Cells (RBC)
- Retinal Products
2 mins
Mannitol (Osmitrol)
- Indications
- Increased Intracranial Pressure (ICP)
- Glaucoma
- Drug Overdose
- Mechanism of Action
- Osmotic diuretic
- Increased Urine Flow
- Side Effects
- Dehydration
- Contraindications
- Anuria
- CHF
2 mins
Acetazolamide
- Indications
- Glaucoma
- Altitude Sickness
- Pseudotumor Cerebri
- CHF
- Metabolic Alkalosis
- Mechanism of Action
- Carbonic Anhydrase Inhibitor
- Sodium Bicarbonate (NaHCO3) Diuresis
- Side Effects
- Metabolic Acidosis
- Paresthesias
1 min
Loop Diuretics
- Mechanism of Action
- Thick Ascending Limb of Loop of Henle
- Inhibits Na+-K+-2Cl- Symporter
- Sulfa Drug
- Drug Names
- Furosemide
- Lasix
- Side Effects
- Gout
- Ototoxicity
- Hypocalcemia
- Hypokalemia
4 mins
Thiazide Diuretics
- Early Distal Tubule
- Inhibits Na/Cl Reabsorption
- Sulfa Drug
- Hyperglycemia
- Hyperlipidemia
- Hypercalcemia
- Hyperuricemia
- Hyponatremia
- Hypokalemic Metabolic Alkalosis
2 mins
K+ Sparing Diuretics
- Indications
- CHF and Hypertension
- Hypokalemia
- Hyperaldosteronism
- Mechanism of Action
- Collecting Tubule
- Spironolactone
- Competitive Aldosterone Receptor Antagonist
- Amiloride and Triamterene
- Block Na+ Channels
- Side Effects
- Hyperkalemia
- Gynecomastia
2 mins
ACE Inhibitors
- -Pril Suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Inhibits ACE
- Decreases GFR
- Inhibits Constriction of Efferent Arteriole
- Side Effect
- Increased Bradykinin
- Cough
1 min
Angiotensin Receptor Blockers (ARBs)
- -sartan suffix
- Indications
- Hypertension
- CHF
- Diabetic Nephropathy
- Mechanism of Action
- Angiotensin II Receptor Blockers
- Side Effect
- Hyperkalemia
- Contraindication
- Pregnancy
1 min
Calcium Channel Blockers (Verapamil and Diltiazem)
- Mechanism of Action
- Slows AV Conduction
- Indications
- Angina Pectoris
- Arrhythmias
- Essential Hypertension
- Side Effects
- Bradycardia
- Hypotension
- Constipation
- Peripheral Edema
- Gingival Hyperplasia
- Nursing Consideration
- Medication Education
2 mins
Systemic Effects of Beta-Blockers
- Respiratory
- Bronchoconstriction
- Metabolic
- Decreased Insulin
- Decreased Glycolysis and Lipolysis
- Eye
- Reduces Intraocular Pressure
1 min
Selective Alpha-1 Blockers
- "-osin" suffix
- Mechanism of Action
- Blocks Alpha1 Receptors
- Indications
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Side Effects
- Syncope
- Orthostatic Hypotension
1 min
Alpha-2 Agonists (Sympathoplegics)
- Indications
- Hypertension
- Renal disease
- Mechanism of Action
- Centrally acting Alpha-2 Agonist
- Drugs
- Clonidine
- Rebound Hypertension
- Alpha-Methyldopa
- Pregnancy
- Coombs (+) Hemolytic Anemia
- SLE Like Syndrome
2 mins
Hydralazine
- Indications
- Reduce Afterload
- Severe Hypertension
- Safe during Pregnancy
- CHF
- Mechanism of Action
- Increases cGMP
- Vasodilates Arterioles
- Side Effects
- Drug-induced Lupus
- Reflex Tachycardia
1 min
Nitroprusside
- Mechanism of Action
- Direct Release of NO
- Increase cGMP
- Short Half-Life
- Indications
- Malignant Hypertension
- Side Effect
- Cyanide Toxicity
1 min
Minoxidil (Loniten, Rogaine)
- Mechanism
- Vasodilates Arterioles
- Indications
- Severe Hypertension
- Baldness
- Side Effects
- Reflex Tachycardia
- Blood Volume Expansion
- Hypertrichosis
- Pericardial Effusion
- Rash
- Considerations
- Give with Beta Blocker and Diuretic
2 mins
Diazoxide
- opens K+ channels
- Causes HAT NAP
- Hyperglycemia
- Emergency Treatment
- Reflex Tachycardia
- insulin decrease
Endothelin Receptor Antagonists
- Indication
- Pulmonary Hypertension
- Mechanism of Action
- Competitive Antagonism of Endothelin Receptors
- Decreased Pulmonary Vascular Resistance
- Drugs
- Bosentan
- Side Effects
- Hepatotoxicity
- Monitor LFTs
1 min
Prostacyclin Analogs
- Mechanism of Action
- Prostaglandin I2 (Prostacyclin)
- Vasodilation of Pulmonary and Systemic Arteries
- Inhibits Platelet Aggregation
- Indications
- Pulmonary Hypertension
- Side effects
- Flushing
- Jaw Pain
- Drugs
- Epoprostenol
- Iloprost
- Treprostinil
1 min
Hypertensive Emergency Diagnosis and Management
- Diagnosis
- Laboratory Tests
- Chest X-ray
- Management
- Decrease Blood Pressure Carefully
- Antihypertensives
- Monitor Vital Signs
2 mins
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