Steven Shared "2015 Study Guide Pathology" - 168 Picmonics
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2015 Study Guide Pathology
Osteogenesis Imperfecta
- Pathophysiology
- Autosomal Dominant
- Decreased Type I Collagen Production
- Symptoms
- Phenotypically Diverse
- Brittle Bone Disease
- Fractures from Minimal Trauma
- Confused with Child Abuse
- Hearing Loss
- Dental Imperfections
- Blue Sclera
1 min
Neurofibromatosis Type 1
- Pathophysiology
- Autosomal Dominant
- Chromosome 17
- Signs and Symptoms
- Neurofibromas
- Optic Glioma
- Lisch Nodules
- Hamartomas
- Cafe Au Lait Spots
- Scoliosis
- Pheochromocytoma
4 mins
Von Hippel-Lindau Disease
- Pathophysiology
- Chromosome 3
- Presentation
- Hemangioblastomas
- Medulla, Retina, Cerebellum
- Cysts
- Kidney, Liver, Pancreas
- Develop Bilateral Renal Carcinomas
- Pheochromocytomas
2 mins
Cystic Fibrosis Diagnosis and Treatment
- Diagnosis
- Sweat Chloride Test > 60 mmol/L
- Meconium Ileus
- Treatment
- N-acetylcysteine
- Antibiotic Prophylaxis
- Pulmonary Maintenance
- Lung Transplant
- Vitamin Replacement
1 min
Cystic Fibrosis Mechanisms
- Autosomal Recessive
- CFTR Chromosome 7
- Cl- channel Defect
- Decreased Chloride Secretion
- Increased Na and Water Reabsorption
- Increased Na and Cl in Sweat
- Dehydration of Mucous Layers
2 mins
Cystic Fibrosis Symptoms and Complications
- Recurrent Pulmonary Infections
- Chronic Bronchitis
- Nasal Polyps
- Pancreatic Insufficiency
- Intestinal Obstruction
- Malabsorption and Diarrhea
- Vitamin Deficiencies
- Chronic Hepatic Disease
- Infertility in Males
1 min
Hemolytic Uremic Syndrome (HUS)
- Children
- Pathophysiology
- Preceded by Acute Diarrheal Illness
- Endothelial Damage
- Classic Triad of Symptoms
- Microangiopathic Hemolytic Anemia (MAHA)
- Thrombocytopenia
- Renal Failure
- Labs
- Helmet cells
- LDH
- Treatment
- Dialysis
- Supportive
2 mins
Hypersensitivity Type I
- Previous Antigen Exposure
- Immediate Reaction
- IgE Cross-linking
- Presensitized Mast Cells
- Histamine Release
- Vasodilation
- Anaphylaxis
- Allergies
- Treatment
- Epinephrine
1 min
Hypersensitivity Type II
- Cytotoxic
- IgM or IgG antibody-mediated
- Membrane Attack Complex (MAC)
- Mechanism
- Opsonization
- Complement Activation
- NK Cells
- Testing
- Direct Coombs test
- Indirect Coombs Test
1 min
Hypersensitivity Type III
- Immune Complex
- Antigen-antibody (IgG) complex activates complement
- Neutrophils release lysozomal enzymes
- Examples
- Arthus Reaction
- Serum Sickness
- Systemic Lupus Erythematosus (SLE)
1 min
Hypersensitivity Type IV
- Delayed-Type Hypersensitivity
- T Cell Mediated
- Antibody Independant
- Macrophages Activated
- Examples
- Transplant Rejection
- PPD Skin Test
- Contact Dermatitis
1 min
Tetralogy of Fallot (TOF)
- Features
- Blue Baby Syndrome
- Mechanism
- PROVe Acronym
- Pulmonary Infundibular Stenosis
- Right Ventricular Hypertrophy
- Overriding Aorta
- Ventricular Septal Defect (VSD)
- Diagnosis and Treatment
- Boot-Shaped Heart
- Squatting for Tet Spells
- Surgery
2 mins
Dilated Cardiomyopathy
- Chronic Alcohol Abuse
- Doxorubicin Toxicity
- Cocaine Use
- Wet Beriberi
- Hemochromatosis
- Coxsackie B
- Chagas Disease
- Peripartum
- S3
- Eccentric Hypertrophy
2 mins
Hypertrophic Cardiomyopathy Mechanisms
- Pathophysiology
- 2/3 Autosomal-Dominant
- 1/3 Sporadic Type
- Mutation in Gene for Sarcomere Protein
- Cardiac Myosin Binding Protein C
- Asymmetric Septal Hypertrophy
- Outflow Tract Obstruction
- Diastolic Dysfunction
2 mins
Restrictive Cardiomyopathy
- Sarcoidosis
- Amyloidosis
- Post-radiation Fibrosis
- Endocardial Fibroelastosis
- Löffler's or Loeffler's Syndrome with Eosinophilia
- Hemochromatosis
2 mins
Hypertrophic Cardiomyopathy Signs, Symptoms and Treatment
- Signs and Symptoms
- Sudden Death Of Young Athlete
- Heart Failure
- Angina
- Arrhythmias
- Syncope
- Harsh Systolic Ejection Murmur
- S4 Heart Sound
- Treatment
- Beta Blocker
- Non-dihydropyridine Calcium Channel Blocker
2 mins
Bacterial Endocarditis
- Signs and Symptoms
- Fever
- New murmur
- Janeway Lesions
- Splinter Hemorrhages
- Roth spots/round white spots on retina
- Osler nodes/tender lesions on finger or toe pads
- Anemia
2 mins
Rheumatic Fever
- Pathophysiology
- Pharyngeal Infection with Strep Pyogenes (Group A Strep)
- Rheumatic Heart Disease
- Signs and Symptoms
- Aschoff Bodies
- Anitschkow's Cells
- Early Death Due to Myocarditis
- Migratory Polyarthritis
- Subcutaneous Nodules
- Erythema Marginatum
- Chorea
- Diagnosis
- Elevated ESR
2 mins
Buerger's Disease
- Pathophysiology
- Thromboangiitis Obliterans
- Segmental Inflammation
- Strong Association with Smoking
- Signs and Symptoms
- Superficial Nodular Phlebitis
- Raynaud's Phenomenon
- Autoamputation
- Treatment
- Smoking Cessation
2 mins
Kawasaki Disease
- Pathophysiology
- Prevalent in Asian Children
- Necrotizing Vasculitis
- Signs and Symptoms
- Fever
- Strawberry-Red Tongue and Mucosa
- Lymphadenopathy
- Desquamative Skin Rash
- Erythema and Edema of the Hands and Feet
- Conjunctivitis
- Coronary Aneurysm
- Treatment
- Intravenous Immunoglobulin (IVIG)
- Aspirin
2 mins
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