Jessica Shared "Derm MSK" - 15 Picmonics
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Derm MSK
Rubeola Virus
- Characteristics
- RNA Virus
- Paramyxovirus
- Signs and Symptoms
- Measles
- Rash Spreads From Head to Toe
- Koplik Spots First
- Red Spots with Blue-White Center on Buccal Mucosa
- Cough
- Coryza
- Conjunctivitis
- Subacute Sclerosing Panencephalitis
- Giant Cell Pneumonia in Immunosuppressed Patients
- Warthin-Finkeldey Multinucleated Giant Cells
- Treatment
- Vitamin A
3 mins
Neurofibromatosis Type 1
- Pathophysiology
- Autosomal Dominant
- Chromosome 17
- Signs and Symptoms
- Neurofibromas
- Optic Glioma
- Lisch Nodules
- Hamartomas
- Cafe Au Lait Spots
- Scoliosis
- Pheochromocytoma
4 mins
Basal Cell Carcinoma of the Skin
- Pathophysiology
- Most Common Skin Cancer
- 2/3 of Cases Due to UV Light Exposure
- Pink, Pearl-like Lesions
- Rolled Borders
- Telangiectasias
- Commonly Upper Lip
- Diagnosis
- Shave Biopsy
- Pallisading Nuclei
- Treatment
- Mohs Micrographic Surgery
2 mins
Melanocytic Nevus
- Characteristics
- Benign Tumor of Melanocytes
- Nested Proliferations at Dermal-Epidermal Junction
- Junctional
- Intradermal
- Risk Factors
- Genetics
- Childhood Sun Exposure
- Considerations
- Melanoma
2 mins
Xeroderma Pigmentosum
- Pathophysiology
- Defective Nucleotide Excision Repair
- Pyrimidine Dimer Accumulation
- Autosomal Recessive
- Susceptible to UVA and UVB Rays
- Presentation
- Actinic Keratosis
- Neurodegeneration
- Photosensitivity
- Corneal Ulcers
- Hyperpigmented Lentigines
- Considerations
- Increased Risk of Skin Cancer
3 mins
Bullous Pemphigoid
- Linear Deposits of IgG
- Affects Hemidesmosomes
- Epidermal Basement Membrane
- Tense Blisters on Skin
- Nikolsky Negative
- Contain Eosinophils
- Rarely Affect Oral Mucosa
2 mins
Pemphigus Vulgaris
- Pathophysiology
- Autoantibodies against desmosomes
- Symptoms
- Flaccid Bullae on Skin
- Oral Mucosa Involvement
- Intraepidermal Acantholysis
- Fluid Loss
- Infection
- Nikolsky Positive
- Diagnosis
- Biopsy showing Autoantibodies
- Treatment
- IVIG and Plasmapheresis
- Oral Steroids
- Immunosuppressants
2 mins
Stevens-Johnson Syndrome
- Etiologies
- Drugs
- Symptoms
- < 10% of Body Surface Area (BSA) Involved
- 10-30% BSA Overlaps with Toxic Epidermal Necrolysis (TEN)
- Fever
- Affects Skin and Mucous Membranes
- Bullae Formation
- Necrosis
- Sloughing of Skin
- High Mortality Rate
- Treatment
- Supportive Care
- IVIG (Intravenous Immunoglobulin)
3 mins
Squamous Cell Carcinoma of the Skin
- Epidemiology
- 2nd Most Common Skin Cancer
- UV Light Exposure
- Long-term Immunosuppression
- Arsenic Exposure
- Signs/Symptoms
- Ulcerative Red Lesion
- Precursor Actinic Keratosis
- Commonly Lower Lip
- Diagnosis
- Biopsy shows Keratin Pearls
- Treatment
- Mohs Micrographic Surgery
2 mins
Actinic Keratosis
- Sun Exposure
- Papules or Plaques
- Small, Rough
- Erythematous
- Precursor to Squamous Cell Carcinoma
53 secs
Keratoacanthoma
- Low-Grade Skin Tumor
- Dome-shaped Nodule with Central Crater
- More Common in Elderly
- Sun-exposed Skin
- Characteristics
- Resembles Squamous Cell Carcinoma of the Skin
- Grows Rapidly over 4-6 Weeks
- Workup & Management
- Wide Excisional Biopsy
- Mohs Micrographic Surgery
2 mins
Types of Malignant Melanoma
- Superficial Spreading
- Most Common Cause of Melanoma
- Nodular
- Aggressive and Rapidly Arising
- Acral-Lentiginous
- Males
- Asians and African Americans
- Lentigo Maligna
- Geographic Shape
- Sun Exposed Areas
2 mins
Neurofibromatosis Type 2
- Pathophysiology
- Autosomal-Dominant
- Chromosome 22
- Signs and Symptoms
- Vestibular Schwannoma
- Meningioma
- Ependymoma
- Cafe Au Lait Spots
- Cataracts
2 mins
Tuberous Sclerosis
- Characteristics
- Autosomal Dominant
- Signs and Symptoms
- Hamartomas in CNS and Skin
- Phakoma
- Subependymal Giant Cell Astrocytoma
- Seizures
- Intellectual Disability (Mental Retardation)
- Adenoma Sebaceum
- Shagreen Patch
- Ash-leaf Spots
- Renal Angiomyolipoma
- Cardiac Rhabdomyoma
2 mins
Fluorouracil (5-FU)
- Mechanism
- Antimetabolite
- "Thymine-less Death"
- Indications
- Slow-growing Solid Tumors
- Co-administered with Leucovorin for Stomach Cancer
- Basal Cell Carcinoma (Topical)
- Side Effects
- Myelosuppression
- Mucositis
- Severe Diarrhea
3 mins
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