Mira Shared "Neuro Pharm 2" - 40 Picmonics

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Neuro Pharm 2

Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Buspirone
Indications
Generalized Anxiety
Mechanism of Action
Releases Dopamine and NE
Stimulates 5-HT1A receptors
Side Effects
Low Side Effect Profile
Safer with Alcohol than Other Anxiolytics
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1 min
IV Anesthetics
Barbiturates
Benzodiazepines
Respiratory Depression
Hypotension
Ketamine
NMDA Receptor Antagonist
Hallucinations
Opioids
Propofol
Potentiates GABA-A
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2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
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39 secs
Zolpidem (Ambien)
Mechanism
Hypnotic
Indications
Insomnia
Side Effects
Daytime Drowsiness
Bizarre Sleep Behaviors
Sleep Driving
Angioedema
Considerations
Short Term Administration
Take Immediately Before Bedtime
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1 min
Nonbenzodiazepine Hypnotics
Indications
Insomnia
Mechanism of Action
Short Half-Life
Acts on BZ1 GABA receptor
Less dependence
Drugs
Zolpidem (Ambien)
Side Effects
Ataxia, confusion
Antidote
Flumazenil for Overdose
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1 min
Barbiturates
Barb- Drug Names
Indications
Seizure Treatment
Anesthesia Induction
Mechanism of Action
Increased Duration of Cl- Channel Opening
Decrease Neuron Firing
Side Effects
Sedation
Cardiovascular and Respiratory Depression
CNS Depression
P450 inducer
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2 mins
Phenobarbital (Barbiturates)
Mechanism
Barbiturate
Indications
Seizures
Side Effects
Ataxia
Paradoxical Excitement
Fatigue/Drowsiness
Considerations
Monitor Plasma Levels
High Potential for Abuse
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1 min
Anaphylaxis Intervention
Intervention
Assess Airway and Oxygen Needs
Reassure Patient with Anxiety
Supine Position
Methylprednisolone (Solu-medrol)
Epinephrine
Diphenhydramine (Benadryl)
Medical Alert Bracelet
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2 mins
Nondepolarizing Neuromuscular Blocking Drugs
Names Include "Cur"
Competitive Antagonists
Acetylcholine Competition
Reversal of Blockade
Neostigmine, Edrophonium
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1 min
Succinylcholine
Indications
Inducing Paralysis
Mechanism of Action
Neuromuscular Blocking Drugs
Motor Nicotinic Receptor
ACh Receptor Agonist
Depolarization
Phases of Action
Phase I (Paralysis Non-reversible)
Phase II (Paralysis Reversible)
Neostigmine (Reversal Agent)
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2 mins
Triazolam (Halcion)
Mechanism
Rapid-Onset Benzodiazepine
Indications
Insomnia
Side Effects
Rebound Insomnia
Respiratory Depression
Hypotension
Paradoxical Excitement
Amnesia
Confusion
Contraindications
Pregnancy
Considerations
Short-Term Administration
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2 mins
Opioid Antidote
Antidote
Naloxone
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28 secs
Opioids Overview
Indications
Pain
Weaning
Cough
Diarrhea
Mechanism of Action
Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
Decrease Synaptic Transmission
Side Effects
Respiratory Depression
Addiction
Miosis
Constipation
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2 mins
Opioid Abuse and Withdrawal Assessment
Abuse Assessment
Euphoria
Miosis
CNS Depression
Abuse Withdrawal
Yawning
Gooseflesh
Sweating
Rhinorrhea
Kicking Movements
Consideration
Naloxone
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1 min
Naloxone (Narcan)
Mechanism
Competitive Opioid Receptor Antagonist
Indications
Opioid Induced CNS Depression
Side Effects
Severe Nausea and Vomiting
Excitable State
Opioid Withdrawal Symptoms
Considerations
Repeated Dosing Often Required
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1 min
Morphine
Mechanism
Opioid Receptor Agonist
Indications
Pain
Myocardial Infarction
Side Effects
Nausea and Vomiting
CNS Depression
Biliary Colic
Constipation
Increased Intracranial Pressure (ICP)
Pupillary Constriction
Hypotension
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2 mins
Meperidine (Demerol)
Mechanism
Opioid Receptor Agonist
Indications
Moderate to Severe Pain
Post Anesthesia Shivering
Side Effects
Tremors
Constipation
CNS Depression
Sedation
Considerations
Short Term Administration
Increased Risk Serotonin Syndrome
Does NOT cause Miosis
Renal Failure Increases Toxicity Risk
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2 mins
Codeine
Mechanism
Opioid Receptor Agonist
Indications
Mild to Moderate Pain
Cough Suppressant
Side Effects
Sedation
Constipation
Miosis
Considerations
Close Monitoring When Breast Feeding
Often Combined with Non-Opioids
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2 mins
Butorphanol
Indications
Migraine
Severe Pain
Labor
Mechanism of Action
Partial Agonist at Mu and Full Agonist at Kappa Receptors
Less Respiratory Depression
Side Effects
Withdrawal Symptoms
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1 min

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