jeremy Shared "reproductive" - 61 Picmonics

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reproductive

5 Alpha Reductase Deficiency
Autosomal Recessive
Inability to Convert Testosterone to DHT
Normal Internal Genitalia
Ambiguous External Genitalia until Puberty
Masculinization During Puberty with Growth of External Genitalia
LH can be Increased
Normal Estrogen, LH, and Testosterone levels
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2 mins
Abruptio Placentae
Mechanism
Premature Separation of Placenta
Assessment
Tearing Pain
Bleeding (Often Concealed)
Rigid Uterus
Contractions
Interventions
Prepare for Vaginal Delivery
Considerations
Increased Risks for Neonate
Rh (Rhesus) Incompatibilities
Increased Risk for Shock
Monitor Fetal Heart Rate
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2 mins
Androgen Insensitivity (Complete)
Defect in androgen receptor
Phenotypically female
(46, XY)
Female external genitalia
Rudimentary Vagina
Scant sexual hair
Testes often in labia majora
Testes surgically removed to prevent malignancy
Increased estrogen, testosterone, and LH
Absent uterus and fallopian tubes
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3 mins
Brenner Tumor
Pathophysiology
Non-germ cell tumor
Transitional epithelium
Benign and unilateral
Coffee bean nuclei
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2 mins
Cervical Cancer Screening
Women aged 21-65 years old
Pap smear every 3 years
Women aged 30-65 years old
Can opt for Co-testing (Pap Smear + HPV testing) every 5 years
Identify lesions
High grade lesions
Cryotherapy
Loop Excision
Cold knife Conization
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2 mins
Choriocarcinoma
Germ-cell tumor
Trophoblastic tissue
Hematogenous spread to lungs
Malignant
Theca-lutein cysts
Hydatidiform Mole
hCG
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59 secs
Cidofovir
Indications
CMV Retinitis
Acyclovir-resistant HSV
Mechanism
Inhibits Viral DNA Polymerase
Side Effects
Nephrotoxicity
Administer with Probenecid and IV Saline
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1 min
Cisplatin
Indications
Carcinomas
Ovarian
Bladder
Lung
Testicular
Mechanism
Cross-Links DNA
Side Effects
Ototoxicity
Nephrotoxicity
Treat with Amifostine and Chloride Diuresis
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2 mins
Ovarian Cystadenocarcinoma
Non-germ Cell Tumor
Mucinous
Peritoneal Spread
Serous
Psammoma Bodies
Bilateral
Malignant
Stromal Invasion
CA 125
BRCA-1 and Lynch Syndrome
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1 min
Ovarian Cystadenoma
Non-germ cell tumor
Serous
Unilocular
Bilateral
Mucinous
Multilocular
Benign
Most Common
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48 secs
Dactinomycin (Actinomycin D)
Indications
Wilms' Tumor
Rhabdomyosarcoma
Ewing's Sarcoma
Gestational Trophoblastic Malignancy
Mechanism
Intercalates DNA
Side Effect
Myelosuppression
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2 mins
Dinoprostone and Misoprostol
Mechanism
Prostaglandins
Indications
Promote Cervical Ripening
Prevent GI Ulcers
Medical Abortion
Side Effects
Fetal Distress
Hyperstimulation of Uterus
Considerations
Vaginal Insertion
Give Before Induction of Labor
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2 mins
Dysgerminoma
Germ-cell tumor
Most Common Malignant Germ Cell Tumor
Uniform Cells
Fried Egg Cells
hCG
LDH
Seminoma-like
Turner Syndrome
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2 mins
Eclampsia
Mechanism of Action
Increased Central Nervous System Irritability
Signs and Symptoms
Hyperreflexia
Positive Ankle Clonus
Headaches
Visual Disturbances
Epigastric or RUQ Pain
Seizures
Coma
Considerations
Don't Leave Bedside
Magnesium Sulfate
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2 mins
Ectopic Pregnancy
Signs and Symptoms
Lower Abdominal Pain
Delayed Menses
Abnormal Vaginal Bleeding
Shock
Referred Shoulder Pain
Cullen Sign
Considerations
Methotrexate
Surgery
RhoGAM
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2 mins
Ejaculation Pathway
SEVEn UP
Seminiferous Tubules
Epididymis
Vas Deferens
Ejaculatory Ducts
Urethra
Penis
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1 min
Endometriosis Characteristics
Endometrial Tissue Outside of Uterus
Glands and Stroma
Most Common in Ovary, Pelvis, Peritoneum and Bowels
"Chocolate Cyst" in Ovary
Adenomyosis
Theories
Retrograde Flow
Metaplastic Transformation
Mullerianosis
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1 min
Endometriosis Symptoms and Treatment
Symptoms
Dysmenorrhea
Cyclic Pelvic Pain
Dyschezia
Dysuria
Dyspareunia
30-40% are Infertile
Treatment
Surgery
NSAIDs
OCPs
Progesterone (Progestins)
GnRH Agonists
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1 min
Ergocalciferol (Vitamin D2)
Mechanism
Vitamin D2
Indications
Hypoparathyroidism
Rickets
Hypophosphatemia
Side Effects
Fatigue
Constipation
Hypercalcemia
Kidney Stones
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2 mins
Fibroadenoma
Most Common Benign Breast Tumor
Stromal Tumor
Presentation
Women under 40
Small, firm mass
Sharp Edges
Increased tenderness and size with Estrogen
Management
Biopsy
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1 min

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