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Epidemiology and Stats - Diagnostic Tests
Quantifying Risk: Contingency 2x2 Table Setup
Along Top (x axis)
Along Side (y axis)
A: Exposed and Diseased (Sick)
B: Exposed and Healthy
C: Not Exposed and Diseased (Sick)
D: Not Exposed and Healthy
TP / (FN+TP)
TN / (TN + FP)
Positive Predictive Value (PPV)
Proportion of Positive Tests that are True Positive
Probability that Person with Positive Test has Disease
TP (True Positives)
Divided by /
All Positive Test Results
TP + FP
Varies Directly with Prevalence
Negative Predictive Value (NPV)
Proportion of Negative Tests that are Truly Negative
Probability that Person with Negative Test is Healthy
(TN) True Negatives
Divided by /
All Negative Test Results
(FN + TN)
Varies Inversely with Prevalence
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