Amy Shared "Thyroid and Antithyroid drugs" - 4 Picmonics
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Thyroid and Antithyroid drugs
Levothyroxine
- Indications
- Hypothyroidism
- Myxedema Coma
- Mechanism of Action
- Isomer of Thyroid Hormone (T4)
- T3 has Higher Potency
- Side Effects
- Hyperthyroid Symptoms
57 secs
Propylthiouracil (PTU) and Methimazole (MMI)
- Indications
- Hyperthyroidism
- Mechanism
- Inhibits Thyroid Peroxidase
- PTU Blocks Peripheral Conversion of T4 to T3
- Side Effects
- Agranulocytosis
- Skin Rash
- Hepatotoxicity (PTU)
- Teratogen (MMI)
1 min
Hyperthyroidism Interventions
- Drug Therapy
- Propylthiouracil (PTU)
- Methimazole (Tapazole)
- Iodine
- Beta Blockers
- Other Therapies
- Radioiodine Ablation
- Thyroidectomy
- Complications
- Thyrotoxicosis
- Post-Surgery Hypocalcemia
2 mins
Thyroid Storm
- Symptoms
- Diarrhea
- Liver Failure
- Insulin Resistance
- Tachycardia
- Lid lag
- Change in LOC (Altered Mental Status)
- High fever
- Treatment
- Propranolol (Or Esmolol)
- PTU (Thionamides) Initially
- Iodine Solution (Lugol Iodine)
- Glucocorticoids
- Cooling Blanket
3 mins
