John Shared "Path Block 3" - 129 Picmonics
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Path Block 3
11 Beta-Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Signs and Symptoms
- Hypertension
- Masculinization
1 min
21 Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Signs and Symptoms
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
2 mins
5 Alpha Reductase Deficiency
- Autosomal Recessive
- Inability to Convert Testosterone to DHT
- Normal Internal Genitalia
- Ambiguous External Genitalia until Puberty
- Masculinization During Puberty with Growth of External Genitalia
- LH can be Increased
- Normal Estrogen, LH, and Testosterone levels
2 mins
Acute Pancreatitis Disease
- Autodigestion of Pancreas by Pancreatic Enzymes
- Symptoms
- Epigastric Abdominal Pain Radiating to Back
- Anorexia
- Nausea
- Labs
- Increased Amylase and Lipase
- Complications
- Disseminated Intravascular Coagulation (DIC)
- Infection
- Hypocalcemia
- Systemic Inflammatory Response Syndrome (SIRS)
- Acute Respiratory Distress Syndrome (ARDS)
- Pancreatic Pseudocyst
- Hemorrhage
3 mins
Acute Gastritis
- Erosive
- Disruption of Mucosal Barrier
- Caused by Stress
- NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)
- Alcohol
- Uremia
- Burns
- Curling's Ulcer
- Brain Injury
- Cushing Ulcer
- Increase H+ Production
1 min
Acute Pancreatitis Causes
- "GET SMASHHED" Mnemonic
- Gallstones
- (Ethanol) Alcohol
- Trauma
- Steroids
- Mumps
- Autoimmune
- Scorpion Sting
- Hypercalcemia
- Hypertriglyceridemia > 1000
- ERCP
- Drugs
1 min
Addison's Disease
- Mechanism
- Chronic 1° Adrenal Insufficiency
- Atrophy
- Destruction
- Symptoms
- Deficiency In Cortisol And Aldosterone
- Skin Hyperpigmentation
- Increased POMC
- Hypotension
- Hyperkalemia
- Acidosis
- Addisonian Crisis
- Diagnosis
- ACTH (Cosyntropin) Stimulation Test
- Treatment
- Exogenous Cortisol
2 mins
Adrenal Gland (Advanced)
- Characteristics
- Adrenal Cortex
- Zona Glomerulosa
- Aldosterone
- Zona Fasciculata
- Cortisol
- Zona Reticularis
- Androgens
- Adrenal Medulla
- Chromaffin Cells
- Epinephrine & Norepinephrine
2 mins
Anterior Pituitary
- Characteristics
- Hypothalamic Control
- FLAT PeG Mnemonic
- Tropic Hormones
- Follicle-Stimulating Hormone (FSH)
- Lutenizing Hormone (LH)
- Adrenocorticotropic Hormone (ACTH)
- Thyroid-Stimulating Hormone (TSH)
- Direct Hormones
- Prolactin (PRL)
- Growth Hormone (GH)
2 mins
Appendicitis
- Mechanism and Characteristics
- Fecalith leading to obstruction and infection
- Most commonly affects teenagers
- Presentation
- Initial peri-umbilical visceral pain
- Subsequent somatic right lower quadrant pain
- Diagnosis
- Rebound tenderness
- Positive psoas sign
- Pain at McBurney's point
- Leukocytosis
- Fever
- Treatment
- Appendectomy
1 min
Barrett's Esophagus
- Histological findings
- Metaplasia in Lower Esophagus
- Columnar Epithelium
- Associated Pathologies
- Gastroesophageal Reflux Disease (GERD)
- Esophagitis
- Esophageal Ulcers
- Increased Risk of Esophageal Adenocarcinoma
1 min
Benign Prostatic Hyperplasia (BPH) Diagnosis and Treatment
- Diagnosis
- Digital Rectal Exam
- Urinalysis to Detect Infection or Blood
- Treatment
- Alpha-1 Antagonists
- Tamsulosin
- 5 Alpha Reductase Inhibitors
- Finasteride
- TURP (Transurethral Resection of Prostate)
1 min
Benign Prostatic Hyperplasia (BPH) Disease
- Mechanism and Characteristics
- DHT-induced Growth Factors
- Common in Men > 50 Years Old
- Smooth, Symmetric, Firm Enlargement
- Affects Lateral and Middle (Periurethral) Gland
- Urethra Compression
- Symptoms and Complications
- Increased Urinary Frequency
- Nocturia
- Dysuria
- Urinary Tract Infection
- Hydronephrosis
1 min
Boerhaave Syndrome
- Pathophysiology
- Esophageal Rupture
- Increased Esophageal Pressure while Vomiting
- Lower 1/3 of Esophagus
- Signs and Symptoms
- Chest Pain
- Odynophagia
- Subcutaneous Emphysema
- Management
- Shock
- Surgical Emergency
2 mins
Bordetella pertussis
- Pathophysiology
- Gram-Negative
- Coccobacillus
- Bordet-Gengou Agar
- ADP Ribosylating AB Toxin
- Inhibits Gi to cause Increase in cAMP
- Signs AND Symptoms
- Lymphocytosis
- Increase in Insulin
- Catarrhal Phase is Infectious Period
- Paroxysmal Phase is Symptomatic Period
- Whooping Cough
- Treatment
- Macrolides
4 mins
Brenner Tumor
- Pathophysiology
- Non-germ cell tumor
- Transitional epithelium
- Benign and unilateral
- Coffee bean nuclei
2 mins
Carcinoid Syndrome
- Pathophysiology
- Neuroendocrine Cells
- Serotonin
- Appendix
- Diagnosis
- Chromogranin A
- Neuron Specific Enolase
- Dense Core Bodies on EM
- Signs and Symptoms
- Symptoms When Metastasize to Liver
- Flushing
- Wheezing
- Right Heart Murmur
- Diarrhea
4 mins
Chlamydia trachomatis
- Characteristics
- A to C
- Trachoma
- Follicular Conjunctivitis
- Blindness
- Africa
- L1 to 3
- Lymphogranuloma venereum
- Buboes
- Genital Ulcer
- D to K
- Urethritis and PID
- Neonatal Pneumonia
- Staccato Cough
- Neonatal Conjunctivitis
2 mins
Choriocarcinoma
- Germ-cell tumor
- Trophoblastic tissue
- Hematogenous spread to lungs
- Malignant
- Theca-lutein cysts
- Hydatidiform Mole
- hCG
59 secs
Chronic Gastritis
- Type A
- Type A
- Fundus and Body
- Autoimmune
- Autoantibodies to Parietal Cells
- Pernicious Anemia
- Achlorhydria
- Type B
- Type B
- Most Common Type
- Helicobacter pylori
- Antrum
- Increased Risk of MALT Lymphoma
- Associations
- HIV/AIDS
- Crohn's Disease
3 mins
