Chris Shared "Micro Exam 3" - 21 Picmonics

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Micro Exam 3

Epstein Barr Virus Mononucleosis
Mononucleosis
Fever
Hepatomegaly
Splenomegaly
Pharyngitis
Posterior Cervical Lymphadenopathy
Atypical Lymphocytes
Heterophile Antibodies
Rash Develops if treated with Ampicillin
Hodgkin's Lymphoma
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2 mins
Cytomegalovirus (CMV)
Characteristics
Enveloped
Double Stranded DNA
Herpesvirus 5
Diagnosis
Non Heterophile Antibodies
Owl's eye inclusions
Signs and Symptoms
Congenital TORCH infection
Mononucleosis
Pneumonia
AIDS retinitis and esophagitis
Infection in transplant recipients
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2 mins
Varicella (Chickenpox)
Mechanism
Varicella Zoster Virus (VZV)
Signs and Symptoms
Red Maculopapular Rash
Vesicles Ooze and Crust
Pruritus
Centripetal
Considerations
Varicella Immunization
Skin Care to Minimize Itching
Isolate until Vesicles Crust
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2 mins
Varicella Zoster Virus (VZV)
Herpesvirus 3
Characteristics
Enveloped
Double Stranded DNA
Signs and Symptoms
Chickenpox
Pneumonia
Encephalitis
Trigeminal and Dorsal Root Ganglia
Shingles
Diagnosis
Tzanck Test
Multinucleated Giant Cells
Cowdry A Inclusion
Treatment
Acyclovir
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2 mins
Human Papillomavirus (HPV)
Characteristics
Non-enveloped
Circular
Double Stranded DNA
Disease
Warts 1, 2, 6, 11
Condyloma acuminata
Type 16, 18
Cervical Carcinoma
Penile Carcinoma
AIDS/Immunocompromised
Worsened by Smoking
Diagnosis
Koilocytic change in squamous epithelium
Pyknotic Nuclei Surrounded by Clear Halo
Treatment
Vaccine Available
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4 mins
Epstein Barr Virus
Characteristics
Herpesvirus 4
Double Stranded DNA
Linear
Enveloped
Signs and Symptoms
Infectious Mononucleosis
Virus Attaches to CD21 in B Cells
Nasopharyngeal Carcinoma
Burkitt's Lymphoma
Hodgkin's Lymphoma
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1 min
Pneumocystis jirovecii
Fungi
AIDS/Immunocompromised
Fever
Hypoxemia
Bronchoalveolar Lavage
Biopsy
Methenamine Silver Stain
Saucer/cup shaped yeast forms
Diffuse interstitial pneumonia CXR
TMP-SMX
Start prophylaxis when CD4 drops under 200
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1 min
Sporothrix Schenckii
Characteristics
Fungi
Thermally Dimorphic
Cigar-shaped Yeast Forms
Rose Thorn Prick
Packaging Peat Moss
Signs & Symptoms
Local Pustule or Ulcer
Nodules on Draining Lymphatics
Treatment
Potassium Iodide
Itraconazole
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2 mins
Candida Albicans
Fungi
Yeast with Pseudohyphae at 20 Degrees C
Germ Tube Formation at 37 Degrees C
Pruritic Vaginitis
White Cottage Cheese Discharge
Fiery Red Mucosa
Diabetics
Antibiotic Use
Esophageal Thrush in Immunocompromised
Diaper Rash
Endocarditis in IV Drug Users
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2 mins
Mucor and Rhizopus
Characteristics
Fungi
Irregular Non-septate Hyphae
Branching Wide Angles over 90 degrees
Signs and Symptoms
Leukemic Patients
Proliferate due to excess ketones and glucose
Diabetic Ketoacidosis (DKA)
Rhinocerebral frontal lobe abscess
Penetrate cribriform plate into brain
Black Necrotic Eschars on Face
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2 mins
Aspergillus fumigatus
Characteristics
Fungi
Monomorphic
Septate Hyphae
Branch at Acute Angles
Fruiting Bodies
Disease
Allergic Bronchopulmonary Aspergillosis (ABPA)
Eosinophilia
Increased IgE
Glucocorticoids +/- Azoles
Pulmonary Aspergillosis
TB Cavity
Lung Aspergilloma
Hemoptysis
Invasive Aspergillosis
AIDS/Immunocompromised
Chronic Granulomatous Disease
Hemorrhagic Infarction
Necrotizing Bronchopneumonia
Voriconazole +/- Caspofungin
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3 mins
Blastomyces
Characteristics
Fungi
Hyphae Form at 20°-25°C
Yeast Form at 37°C
Round Yeast
5-15 Micrometer (um or μm)
Single Broad-Based Buds
Thick Doubly-Refractive Walls
East of the Mississippi River and Around the Great Lakes
Signs and Symptoms
Pneumonia
Skin Infection
Bone Infection
Granulomatous Response
Treatment
Itraconazole
Amphotericin B
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3 mins
Coccidioidomycosis
Characteristics
Fungi
Dimorphic
Southwest
After earthquakes
Spherule
20-60 um
Signs and Symptoms
Pneumonia
Meningitis
Bone Infection
Skin infections
Erythema Nodosum
Granulomatous Inflammation
Caseous Necrosis
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2 mins
Histoplasmosis
Fungi
2-5 um
Yeast Cells within Macrophages
Starling Bird Poop
Bat Poop
Caves
Mississippi and Ohio River Valleys
Pneumonia
Caseating Granuloma
Erythema Nodosum
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1 min
Cryptococcus neoformans
Characteristics
Monomorphic
Encapsulated
Polysaccharide Capsule
Narrow-Based Buds
Latex Agglutination
Pigeons
India Ink
Mucicarmine stain
Signs and Symptoms
AIDS/Immunocompromised
Meningitis
Soap Bubble Lesions in Brain
Pneumonia
Treatment
Fluconazole
Flucytosine
Amphotericin
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3 mins
Pityriasis Versicolor (Tinea versicolor)
Mechanism
Lipid-Dependent Fungus
Fatty Acids Damage Melanocytes
Malassezia Furfur
Hot, Humid Weather
Signs and Symptoms
Hypopigmentation
Hyperpigmented Patches
Diagnosis
Spaghetti and Meatball Appearance on KOH Prep
Fragmented Hyphae with Clusters of Yeast
Treatment
Topical or Oral Antifungals
Selenium Sulfide
Zinc
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4 mins
Terbinafine
Indications
Dermatophytosis
Onychomycosis
Mechanism
Inhibits Squalene Epoxidase
Side Effects
Hepatotoxicity
GI Distress
Taste Disturbances
Headache
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2 mins
Azoles (Ketoconazole)
"-azole" suffix
Indications
Local and Less Serious Systemic Mycosis
Mechanism
Inhibits Ergosterol Synthesis
Inhibits P450
Side Effects
Liver Dysfunction
Inhibition of Testosterone Synthesis
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1 min
Echinocandins
"-Fungin" suffix
Indications
Invasive Aspergillosis
Candida
Mechanism
Inhibits Cell Wall Synthesis
Inhibits Synthesis of Beta-glucan
Side Effects
GI Distress
Flushing
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1 min
Acyclovir (Zovirax)
Mechanism
Guanosine Analog
Inhibits Viral Replication
Thymidine Kinase Activation
Indications
Herpes Simplex Virus (HSV)
Varicella Zoster Virus (VZV)
Side Effects (Oral)
Headache
GI Distress
Side Effects (IV)
CNS Toxicity
Nephrotoxicity (Crystalline Nephropathy)
Considerations
Prevents Recurrent Episodes
Slow IV Infusion
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2 mins

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