Brandon Shared "Repro Test 4" - 24 Picmonics
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Repro Test 4
Fibroadenoma
- Most Common Benign Breast Tumor
- Stromal Tumor
- Presentation
- Women under 40
- Small, firm mass
- Sharp Edges
- Increased tenderness and size with Estrogen
- Management
- Biopsy
1 min
Intraductal Papilloma
- Presentation
- Bloody nipple discharge
- Women 20-40 years old
- Mechanism
- Small tumor in lactiferous ducts
- Occurs Centrally
- Occurs Peripherally
- Increased malignancy
- Diagnosis
- Too Small to Palpate
- Galactogram biopsy
1 min
Phyllodes Tumor
- Presentation
- Common in 40's
- Large Palpable Mass
- Mechanism
- Benign
- Rarely Malignant
- Low-Grade Tumor
- Leaf-Like
- Stromal Tumor
- Treatment
- Wide Resection
2 mins
Breast Cancer Diagnosis
- Mammography
- Ultrasound
- MRI for High Risk Patients
- Confirmed with Biopsy
- Considerations
- Lymph Node Involvement
- Receptor Positivity
- Estrogen and Progesterone Receptors
- HER-2
2 mins
Spermatogenesis
- Seminiferous Tubules
- Sertoli Cells
- Spermatogonia
- Mitosis
- Primary Spermatocyte
- Meiosis I
- Secondary Spermatocyte
- Meiosis II
- Spermatid
- Spermatozoa
- Acrosome
- Flagellum
2 mins
Klinefelter's Syndrome
- Pathophysiology
- Male (XXY)
- Signs and Symptoms
- Eunuchoid Body Shape
- Gynecomastia and Female Hair Distribution
- Testicular Atrophy
- Dysgenesis of Seminiferous Tubules
- Possible Developmental Delay
- Hypogonadism
- Decreased Inhibin B
- Increased FSH
- Abnormal Leydig Cell Function
- Decreased Testosterone
- Increased LH
- Increased Estrogen
- Barr body (inactivated X chromosome)
6 mins
5 Alpha Reductase Deficiency
- Autosomal Recessive
- Inability to Convert Testosterone to DHT
- Normal Internal Genitalia
- Ambiguous External Genitalia until Puberty
- Masculinization During Puberty with Growth of External Genitalia
- LH can be Increased
- Normal Estrogen, LH, and Testosterone levels
2 mins
Placental Implantation Abnormalities
- Mechanism
- Placenta Adheres Directly to Myometrium
- Placenta Accreta
- Placenta Increta
- Placenta Percreta
- Caused by Scar Tissue
- Hemorrhage
- Diagnosis
- Ultrasound is First-line, then MRI
- Treatment
- C-section Delivery
- Artery Ligation or Embolization
2 mins
Abruptio Placentae
- Mechanism
- Premature Separation of Placenta
- Assessment
- Tearing Pain
- Bleeding (Often Concealed)
- Rigid Uterus
- Contractions
- Interventions
- Corticosteroids as Needed
- Emergent Delivery
- Considerations
- Increased Risks for Neonate
- Rh (Rhesus) Incompatibilities
- Increased Risk for Shock
- Monitor Fetal Heart Rate
3 mins
Placenta Previa
- Mechanism
- Placenta Covers Cervical Os
- Assessment
- Painless
- Bright Red Vaginal Bleeding
- Interventions
- Stable Fetus
- Bed Rest
- Observation
- Unstable Fetus
- C-section Delivery
- Considerations
- Risk for Shock
- Magnesium Sulfate
- Tocolysis
3 mins
Ectopic Pregnancy
- Signs and Symptoms
- Lower Abdominal Pain
- Delayed Menses
- Abnormal Vaginal Bleeding
- Shock
- Referred Shoulder Pain
- Cullen Sign
- Considerations
- Methotrexate
- Surgery
- RhoGAM
2 mins
Benign Prostatic Hyperplasia (BPH) Disease
- Mechanism and Characteristics
- DHT-induced Growth Factors
- Common in Men > 50 Years Old
- Smooth, Symmetric, Firm Enlargement
- Affects Lateral and Middle (Periurethral) Gland
- Urethra Compression
- Symptoms and Complications
- Increased Urinary Frequency
- Nocturia
- Dysuria
- Urinary Tract Infection
- Hydronephrosis
1 min
Benign Prostatic Hyperplasia (BPH) Diagnosis and Treatment
- Diagnosis
- Digital Rectal Exam
- Urinalysis to Detect Infection or Blood
- Treatment
- Alpha-1 Antagonists
- Tamsulosin
- 5 Alpha Reductase Inhibitors
- Finasteride
- TURP (Transurethral Resection of Prostate)
1 min
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
Aromatase Inhibitors
- Indications
- Estrogen Receptor-positive (ER+) Breast Tumors
- Systemic Metastases
- Drugs
- Reversible, non-steroid
- Letrozole
- Anastrozole
- Irreversible, steroid
- Exemestane
- Side Effects
- Osteoporosis
- Arthritis
1 min
Testes
- Characteristics
- FSH Stimulates Sertoli Cells
- Inhibin B Release
- LH Stimulates Leydig Cells
- Leydig Cells Secrete Testosterone
- Testosterone Causes Male Development
2 mins
Gardnerella vaginalis
- Signs and Symptoms
- Bacterial Vaginosis
- Not an STD
- Fishy Smell
- Whiff Test
- Grey Vaginal Discharge
- Increase pH
- Clue Cells
- Squamous Epithelial Cells Covered with Bacteria
- Mobiluncus Coinfection
- Treatment
- Metronidazole
2 mins
Tetracycline Mechanism
- Binds to 30 S to Prevent Attachment of Aminoacyl tRNA
- Limited CNS Penetration
- Divalent Cations Inhibit Absorption
- Must Not Take with Milk, Antacids, Iron
1 min
Protein Synthesis Inhibitors
- Drug Names
- 30S inhibitors
- Aminoglycosides
- Tetracyclines
- 50S inhibitors
- Chloramphenicol
- Clindamycin
- Erythromycin
- Lincomycin
- Linezolid
3 mins
Gonorrhea
- Mechanism
- Neisseria gonorrhoeae
- Assessment
- Dysuria
- Yellowish-Green Discharge
- Increased Urinary Frequency
- Women Often Asymptomatic
- Interventions
- Ceftriaxone (IM)
- Chlamydia
- Doxycycline
- Azithromycin
- Considerations
- Treat Partners
2 mins
