Amy Shared "Central Nervous System Depressants and Muscle Relaxants" - 9 Picmonics

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Central Nervous System Depressants and Muscle Relaxants

Barbiturates
Barb- Drug Names
Indications
Seizure Treatment
Anesthesia Induction
Mechanism of Action
Increased Duration of Cl- Channel Opening
Decrease Neuron Firing
Side Effects
Sedation
Cardiovascular and Respiratory Depression
CNS Depression
P450 inducer
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2 mins
Phenobarbital (Barbiturates)
Mechanism
Barbiturate
Indications
Seizures
Side Effects
Ataxia
Paradoxical Excitement
Fatigue/Drowsiness
Considerations
Monitor Plasma Levels
High Potential for Abuse
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1 min
Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Benzodiazepine Antidote
Antidote
Flumazenil
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39 secs
Zolpidem (Ambien)
Mechanism
Hypnotic
Indications
Insomnia
Side Effects
Daytime Drowsiness
Bizarre Sleep Behaviors
Sleep Driving
Angioedema
Considerations
Short Term Administration
Take Immediately Before Bedtime
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1 min
Nonbenzodiazepine Hypnotics
Indications
Insomnia
Mechanism of Action
Short Half-Life
Acts on BZ1 GABA receptor
Less dependence
Drugs
Zolpidem (Ambien)
Side Effects
Ataxia, confusion
Antidote
Flumazenil for Overdose
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1 min
Hypnotic Benzodiazapines
azopam or azolam ending
Hypnotics
Estazolam (Prosom)
Prosom
Flurazepam (Dalmane)
Dalmane
Quazepam (Doral)
Doral
Triazolam (Halcion)
Halcion
Temazepam (Restoril)
Restoril
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Baclofen
Mechanism
Potentiates GABA-B at spinal cord level
Skeletal Muscle Relaxation
Indications
Muscle Spasms
Multiple Sclerosis
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Cyclobenzaprine (Flexeril)
Mechanism
Centrally-Acting Muscle Relaxer
Act on Alpha and Gamma Motor Neurons
Related to Tricyclic Antidepressants (TCAs)
Uses
Muscle Spasms
Back Pain
Side Effects/Interactions
MAO Inhibitors
Serotonin Syndrome
Drowsiness
Arrhythmia
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3 mins

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