Manderson39 Shared "neuro" - 27 Picmonics
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neuro
Wilson's Disease Pathophysiology
- Autosomal Recessive
- Mutation in ATP7B gene
- Chromosome 13
- Decrease in Ceruloplasmin
- Inadequate copper excretion
- Liver
- Brain
- Kidney
- Cornea
- Joints
- Treat with Penicillamine
2 mins
Lewy Body Dementia
- Pathophysiology
- Unknown Etiology
- Decreased Acetylcholine
- Alpha-synuclein Defect
- Eosinophilic Cytoplasmic Inclusion
- Signs and Symptoms
- Visual Hallucinations
- Progressive Dementia
- Fluctuating Cognition
- REM Sleep Behavior Disorder
- Parkinsonism
- Treatment
- Acetylcholinesterase Inhibitors
3 mins
Huntington's Disease
- Pathophysiology
- Autosomal Dominant
- Trinucleotide Repeat
- CAG Repeats
- Chromosome 4
- Anticipation
- Caudate
- Decrease of ACh
- Decrease of GABA
- Signs and Symptoms
- Chorea
- Dementia
- Depression
- Glutamate Toxicity
- Neuronal Death via NMDA Binding
3 mins
Parkinson's Disease Assessment
- Assessment
- Decreased Dopamine
- Older Adult
- Cogwheel Rigidity
- Bradykinesia
- Shuffling Gait
- Resting Tremor
- Pill-Rolling
- Mask-Like Face
- Cognitive Decline
2 mins
Varicella Zoster Virus (VZV)
- Herpesvirus 3
- Characteristics
- Enveloped
- Double Stranded DNA
- Signs and Symptoms
- Chickenpox
- Pneumonia
- Encephalitis
- Trigeminal and Dorsal Root Ganglia
- Shingles
- Diagnosis
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusion
- Treatment
- Acyclovir
2 mins
Meningitis Assessment
- Assessment
- Nausea and Vomiting
- Fever
- Nuchal Rigidity
- Severe Headache
- Purpura
- Seizures
- Photophobia
- Infants and Young Children
- Opisthotonus Position
- High-Pitched Cry
- Bulging Fontanel
2 mins
Haemophilus influenzae Characteristics
- Characteristics
- Gram-Negative
- Coccobacilli
- PRP Capsule in Type B
- Positive Quellung Reaction
- IgA Protease
- Chocolate Agar
- Factor V is NAD
- Factor X is Hematin
- Staph Aureus Provides Factor V
2 mins
Streptococcus Pneumoniae Characteristics
- Characteristics
- Gram-Positive
- Diplococci
- Lancet-Shaped
- Catalase-Negative
- Optochin-Sensitive
- Bile Soluble
- Alpha-Hemolytic
- Polysaccharide Capsule
- Positive Quellung Reaction
- IgA Protease
1 min
Neisseria Meningitidis
- Characteristics
- Gram-Negative
- Diplococci
- Chocolate Agar
- Thayer-Martin Media
- VPN
- Oxidase-Positive
- Maltose Fermentation
- Glucose Fermentation
- Endotoxin
- Lipooligosaccharide (LOS) in Membrane
- Polysaccharide Capsule
- IgA Protease
- Disease
- Waterhouse Friderichsen Syndrome
- Adrenal Insufficiency
- Petechial Rash
- Treatments
- Ceftriaxone
- Rifampin Prophylaxis
5 mins
Pick's Disease (Frontotemporal Dementia)
- Epidemiology
- Affects People Aged 45 to 65.
- Pathophysiology
- Frontal and Temporal Lobes
- Occipital and Parietal Lobes are Spared
- Tauopathy
- Neuronal Apoptosis
- Clinical Features
- Dementia
- Personality Changes, Impaired Judgment, Apathy, and Disinhibition
- Behavioral Variant
- Primary Progressive Aphasia
- Diagnosis Based on Clinical Features and Imaging
- Management
- Supportive Care
5 mins
Schwannoma
- Characteristics
- Acoustic Schwannoma
- Cranial Nerve VIII
- Cerebellopontine Angle
- S100 Positive
- Bilateral Schwannoma in Neurofibromatosis Type 2
- Tinnitus
- Cranial Nerve V
- Affects Corneal Reflex
2 mins
Amyotrophic Lateral Sclerosis (ALS)
- Assessment
- Progressive Muscle Weakness
- Systemic Muscle Wasting
- Fasciculations
- Spasticity
- Fatigue
- Considerations
- Riluzole (Rilutek)
- Stretching
- Little to No Cognitive Decline
- Respiratory Support
- Palliative Care
2 mins
Creutzfeldt-Jakob Disease (CJD)
- Pathophysiology
- Misfolded Prion Protein
- Spongiform Encephalopathy
- Subtypes
- Sporadic Type
- Familial Type
- Variant Type
- Iatrogenic Type
- Clinical Manifestations
- Rapidly Progressive
- Dementia
- Ataxia
- Myoclonus
- Diagnosis
- Magnetic Resonance Imaging (MRI)
- Increased Levels of 14-3-3 Protein
- Periodic Sharp Waves On EEG
- Management
- Supportive Care
4 mins
Essential Tremor
- Characteristics
- Most Common Tremor in Adults
- Positive Family History
- Clinical Findings
- Bilateral Upper Extremities
- Worse with Physical and Psychological Stress
- Better with Rest and Alcohol
- Management
- Beta Blockers
- Primidone
1 min
Tay-Sachs Disease
- Pathophysiology
- Autosomal Recessive
- Hexosaminidase A Deficiency
- Increased GM2 Ganglioside
- More Common in Ashkenazi Jewish Population
- Signs and Symptoms
- Cherry Red Spot on Macula
- Neurodegeneration
- Developmental Delay
- Diagnosis
- Onion Skin Lysosomes
1 min
Niemann-Pick Disease
- Pathophysiology
- Autosomal Recessive
- Sphingomyelinase Deficiency
- More Common in Ashkenazi Jewish Population
- Signs and Symptoms
- Cherry Red Spot on Macula
- Hepatosplenomegaly
- Neurodegeneration
- Diagnosis
- Foam Cells
1 min
Gauchers Disease
- Pathophysiology
- Autosomal Recessive
- Beta Glucocerebrosidase Deficiency
- Diagnosis
- Lipid-laden Macrophages
- Crumpled Tissue Paper
- Signs and Symptoms
- Osteoporosis
- Bone Crises
- Aseptic Necrosis of Femur
- Erlenmeyer Flask Deformity
- Hepatosplenomegaly
- Pancytopenia
2 mins
Fabry's Disease
- Pathophysiology
- X-linked Recessive
- Alpha-galactosidase A Deficiency
- Increased Ceramide trihexoside
- Early Signs and Symptoms
- Decreased Sweating (Hypohidrosis)
- Angiokeratoma
- Episodic Peripheral Neuropathy
- Late Signs and Symptoms
- Cardiovascular Disease
- Renal Failure
1 min
Rabies Virus
- Characteristics
- Enveloped
- RNA Virus
- SS Negative Linear
- Helical
- Bullet-Shaped Envelope
- Binds to Acetylcholine Receptor
- Retrograde Fashion
- Migrates to Saliva
- Diagnosis
- Negri Bodies
- Cytoplasmic Inclusions in Neurons
- Purkinje Cells of Cerebellum
2 mins
Hunter Syndrome
- Pathophysiology
- X-linked Recessive
- Mucopolysaccharidoses
- Iduronate Sulfatase Deficiency
- Increased Dermatan Sulfate
- Increased Heparan Sulfate
- Signs and Symptoms
- No Corneal Clouding
- Aggressive Behavior
1 min
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